Search Results - "Leroux, J C"

4D printing of biodegradable elastomers with tailorable thermal response at physiological temperature by Paunović, N., Meyer, D., Krivitsky, A., Studart, A.R., Bao, Y., Leroux, J.-C.

“…4D printing has a great potential for the manufacturing of soft robotics and medical devices. The alliance of digital light processing (DLP) 3D printing and…”
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Releasable and traceless PEGylation of arginine-rich antimicrobial peptides by Gong, Y, Andina, D, Nahar, S, Leroux, J.-C, Gauthier, M. A

“…Arginine-rich antimicrobial peptides (AMPs) are emerging therapeutics of interest. However, their applicability is limited by their short circulation…”
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Thermosensitive chitosan-based hydrogel containing liposomes for the delivery of hydrophilic molecules by Ruel-Gariépy, E., Leclair, G., Hildgen, P., Gupta, A., Leroux, J.-C.

“…A novel injectable in situ gelling thermosensitive chitosan–β-glycerophosphate (C–GP) formulation has been recently proposed for tissue repair and drug…”
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Poly( N-vinylpyrrolidone)-block-poly( d,l-lactide) as a new polymeric solubilizer for hydrophobic anticancer drugs: in vitro and in vivo evaluation by Le Garrec, D., Gori, S., Luo, L., Lessard, D., Smith, D.C., Yessine, M.-A., Ranger, M., Leroux, J.-C.

“…The majority of novel anticancer drugs developed to date are intended for parenteral administration. Paradoxically, most of these drugs are water-insoluble,…”
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Novel injectable neutral solutions of chitosan form biodegradable gels in situ by CHENITE, A, CHAPUT, C, WANG, D, COMBES, C, BUSCHMANN, M. D, HOEMANN, C. D, LEROUX, J. C, ATKINSON, B. L, BINETTE, F, SELMANI, A

“…A novel approach to provide, thermally sensitive neutral solutions based on chitosan/polyol salt combinations is described. These formulations possess a…”
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Preparation and characterization of water-soluble pH-sensitive nanocarriers for drug delivery by Dufresne, M.-H., Garrec, D.Le, Sant, V., Leroux, J.-C., Ranger, M.

“…pH-sensitive drug delivery systems can be engineered to release their contents or change their physicochemical properties in response to variations in the…”
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Characterization of thermosensitive chitosan gels for the sustained delivery of drugs by Ruel-Gariépy, E, Chenite, A, Chaput, C, Guirguis, S, Leroux, J.-C

“…The aim of this study was to investigate the physical properties of a chitosan/glycerophosphate (GP) thermosensitive solution which gels at 37°C and evaluate…”
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Preparation and characterization of pH-responsive polymeric micelles for the delivery of photosensitizing anticancer drugs by Taillefer, J, Jones, M C, Brasseur, N, van Lier, J E, Leroux, J C

“…pH-responsive polymeric micelles (PM) consisting of random copolymers of N-isopropylacrylamide (NIPA), methacrylic acid (MAA), and octadecyl acrylate (ODA)…”
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Optimizing pH-responsive Polymeric Micelles for Drug Delivery in a Cancer Photodynamic Therapy Model by Le Garrec, D., Taillefer, J., Van Lier, J.E., Lenaerts, V., Leroux, J.-C.

“…Different pH-sensitive, randomly- and terminally-alkylated N -isopropylacrylamide (NIPAM) copolymers were synthesized and used to prepare pH-responsive…”
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In-vitro and in-vivo evaluation of pH-responsive polymeric micelles in a photodynamic cancer therapy model by Taillefer, J., Brasseur, N., van Lier, J. E., Lenaerts, V., Garrec, D. Le, Leroux, J.-C.

“…pH‐sensitive polymeric micelles of randomly and terminally alkylated N‐isopropylacrylamide copolymers were prepared and characterized. Aluminium chloride…”
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Novel polymeric micelles based on the amphiphilic diblock copolymer poly(N-vinyl-2-pyrrolidone)-block-poly(D, L-lactide) by BENAHMED, Amina, RANGER, Maxime, LEROUX, Jean-Christophe

“…The purpose of this work was to synthesize a new amphiphilic diblock copolymer of poly(N-vinyl-2-pyrrolidone and poly(D,L-lactide) (PVP-b-PDLLA) capable of…”
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Synthesis and Micellar Characterization of Novel Amphiphilic A−B−A Triblock Copolymers of N-(2-Hydroxypropyl)methacrylamide or N-Vinyl-2-pyrrolidone with Poly(ε-caprolactone) by Lele, B. S, Leroux, J.-C

“…Two novel A−B−A type amphiphilic triblock copolymers, namely…”
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Synthesis of novel amphiphilic star-shaped poly(ε-caprolactone)- block-poly( N-(2-hydroxypropyl)methacrylamide) by combination of ring-opening and chain transfer polymerization by Lele, B.S, Leroux, J.-C

“…Novel amphiphilic star-shaped block copolymer, star-poly(ε-caprolactone)- block-poly( N-(2-hydroxypropyl)methacrylamide), was synthesized and characterized…”
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Enzymatic degradation of cross-linked high amylose starch tablets and its effect on in vitro release of sodium diclofenac by Rahmouni, M, Chouinard, F, Nekka, F, Lenaerts, V, Leroux, J.C

“…The influence of several physicochemical parameters on enzymatic hydrolysis and the in vitro release of sodium diclofenac (SDic) from cross-linked high amylose…”
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Enzyme-Mimetic Antioxidant Luminescent Nanoparticles for Highly Sensitive Hydrogen Peroxide Biosensing by Pratsinis, Anna, Kelesidis, Georgios A, Zuercher, Stefanie, Krumeich, Frank, Bolisetty, Sreenath, Mezzenga, Raffaele, Leroux, Jean-Christophe, Sotiriou, Georgios A

“…Hydrogen peroxide (H2O2) is an abundant molecule associated with biological functions and reacts with natural enzymes, such as catalase. Even though direct…”
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Formulation and lyoprotection of poly(lactic acid-co-ethylene oxide) nanoparticles : Influence on physical stability and in vitro cell uptake by DE JAEGHERE, F, ALLEMANN, E, LEROUX, J.-C, STEVELS, W, FEIJEN, J, DOELKER, E, GURNY, R

“…To investigate the feasibility of producing freeze-dried poly(ethylene oxide) (PEO)-surface modified nanoparticles and to study their ability to avoid the…”
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Evaluation of pegylated lipid nanocapsules versus complement system activation and macrophage uptake by Vonarbourg, A., Passirani, C., Saulnier, P., Simard, P., Leroux, J.C., Benoit, J.P.

“…This work consisted in defining the in vitro behavior of pegylated lipid nanocapsules (LNC) toward the immune system. LNC were composed of an oily core…”
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In vitro extended-release properties of drug-loaded poly(DL-lactic acid) nanoparticles produced by a salting-out procedure by ALLEMANN, E, LEROUX, J.-C, GURNY, R, DOELKER, E

“…Savoxepine-loaded poly(DL-lactic acid) (PLA) nanoparticles were prepared using an emulsion technique involving a salting-out process which avoids surfactants…”
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An investigation on the use of tributyrin nanoemulsions for docetaxel delivery by Perron, M.-È., Plourde, F., Guérard, S., Huynh, L., Allen, C., Leroux, J.-C.

“…Tributyrin, an oil with anticancer properties, is a good solubilizer for docetaxel, an agent used in the treatment of several cancers. In this paper, the…”
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pH-sensitive nanoparticles : An effective means to improve the oral delivery of HIV-1 protease inhibitors in dogs by LEROUX, J.-C, COZENS, R. M, ROESEL, J. L, GALLI, B, DOELKER, E, GURNY, R

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