Search Results - "Lerner, H."

The WNT system: background and its role in bone by Lerner, U. H., Ohlsson, C.

“…WNTs are extracellular proteins that activate different cell surface receptors linked to canonical and noncanonical WNT signalling pathways. The Wnt genes were…”
Get full text

The gut microbiota regulates bone mass in mice by Sjögren, Klara, Engdahl, Cecilia, Henning, Petra, Lerner, Ulf H, Tremaroli, Valentina, Lagerquist, Marie K, Bäckhed, Fredrik, Ohlsson, Claes

“…The gut microbiota modulates host metabolism and development of immune status. Here we show that the gut microbiota is also a major regulator of bone mass in…”
Get full text

Vitamin A - discovery, metabolism, receptor signaling and effects on bone mass and fracture susceptibility by Lerner, Ulf H

“…The first evidence of the existence of vitamin A was the observation 1881 that a substance present in small amounts in milk was necessary for normal…”
Get full text

The critical interplay between bone resorbing and bone forming cells by Lerner, Ulf H., Kindstedt, Elin, Lundberg, Pernilla

“…Aim In this article, the interplay between bone resorbing and bone forming cells is reviewed. Method This review examines the comprehensive literature on the…”
Get full text

Vitamin A Metabolism, Action, and Role in Skeletal Homeostasis by Conaway, H. Herschel, Henning, Petra, Lerner, Ulf H

“…Vitamin A (retinol) is ingested as either retinyl esters or carotenoids and metabolized to active compounds such as 11-cis-retinal, which is important for…”
Get full text

When Someone Other than the Addressed Recipient Speaks Next: Three Kinds of Intervening Action After the Selection of Next Speaker by Lerner, Gene H.

“…Although speakers in conversation have ways to indicate which one of their recipients ought to speak next, who actually comes to speak next is not an automatic…”
Get full text

Finding a Toll on the Route: The Fate of Osteoclast Progenitors After Toll-Like Receptor Activation by Souza, Pedro P C, Lerner, Ulf H

“…M-CSF and RANKL are two crucial cytokines stimulating differentiation of mature, bone resorbing, multinucleated osteoclasts from mononucleated progenitor cells…”
Get full text

Toll-Like Receptor 2 Stimulation of Osteoblasts Mediates Staphylococcus Aureus Induced Bone Resorption and Osteoclastogenesis through Enhanced RANKL by Kassem, Ali, Lindholm, Catharina, Lerner, Ulf H

“…Severe Staphylococcus aureus (S. aureus) infections pose an immense threat to population health and constitute a great burden for the health care worldwide…”
Get full text

Bone Remodeling in Post-menopausal Osteoporosis by Lerner, U.H.

“…Bone mass in the skeleton is dependent on the coordinated activities of bone-forming osteoblasts and bone-resorbing osteoclasts in discrete bone multi-cellular…”
Get full text

Inflammation-induced Bone Remodeling in Periodontal Disease and the Influence of Post-menopausal Osteoporosis by Lerner, U.H.

“…During physiological conditions, the skeleton is remodeled in so-called bone multi-cellular units. Such units have been estimated to exist at 1–2 x 106 sites…”
Get full text

Porphyromonas gingivalis Stimulates Bone Resorption by Enhancing RANKL (Receptor Activator of NF-κB Ligand) through Activation of Toll-like Receptor 2 in Osteoblasts by Kassem, Ali, Henning, Petra, Lundberg, Pernilla, Souza, Pedro P.C., Lindholm, Catharina, Lerner, Ulf H.

“…Periodontitis has been associated with rheumatoid arthritis. In experimental arthritis, concomitant periodontitis caused by oral infection with Porphyromonas…”
Get full text

Vitamin A - a scoping review for Nordic nutrition Recommendations 2023 by Olsen, Thomas, Lerner, Ulf H

“…Vitamin A refers to a group of fat-soluble compounds with retinol activity, including all- retinol and pro-vitamin A carotenoids. Bioactive compounds include…”
Get full text

Well-Prefacing in the Organization of Self-Initiated Repair by Lerner, Gene H., Kitzinger, Celia

“…This report describes the use of well as a preface to repair solutions in self-initiated repair segments. It extends our previous work on repair prefacing,…”
Get full text

The PerioGene North Study Uncovers Serum Proteins Related to Periodontitis by Wänman, M., Betnér, S., Esberg, A., Holm, C.K., Isehed, C., Holmlund, A., Palmqvist, P., Lövgren, A., Lindquist, S., Hänström, L., Lerner, U.H., Kindstedt, E., Lundberg, P.

“…The sequalae of periodontitis include irreversible degradation of tooth-supporting structures and circulatory spread of inflammatory mediators. However, the…”
Get full text

TLR5, a novel mediator of innate immunity‐induced osteoclastogenesis and bone loss by Kassem, Ali, Henning, Petra, Kindlund, Bert, Lindholm, Catharina, Lerner, Ulf H.

“…ABSTRACT Accumulating evidence points to the importance of the innate immune system in inflammation‐induced bone loss in infectious and autoimmune diseases…”
Get full text

Stimulation of Osteoclast Formation by Oncostatin M and the Role of WNT16 as a Negative Feedback Regulator by de Souza, Pedro P C, Henning, Petra, Lerner, Ulf H

“…Oncostatin M (OSM), which belongs to the IL-6 family of cytokines, is the most potent and effective stimulator of osteoclast formation in this family, as…”
Get full text

GREM2 inactivation increases trabecular bone mass in mice by Nilsson, Karin H., Henning, Petra, Wu, Jianyao, Sjögren, Klara, Lerner, Ulf H., Ohlsson, Claes, Movérare-Skrtic, Sofia

“…Osteoporosis is a common skeletal disease affecting millions of individuals world-wide, with an increased risk of fracture, and a decreased quality of life…”
Get full text

The petrologic and degassing behavior of sulfur and other magmatic volatiles from the 2018 eruption of Kīlauea, Hawaiʻi: melt concentrations, magma storage depths, and magma recycling by Lerner, Allan H., Wallace, Paul J., Shea, Thomas, Mourey, Adrien J., Kelly, Peter J., Nadeau, Patricia A., Elias, Tamar, Kern, Christoph, Clor, Laura E., Gansecki, Cheryl, Lee, R. Lopaka, Moore, Lowell R., Werner, Cynthia A.

“…Kīlauea Volcano’s 2018 lower East Rift Zone (LERZ) eruption produced exceptionally high lava effusion rates and record-setting SO 2 emissions. The eruption…”
Get full text

Rapid and slow: Varying magma ascent rates as a mechanism for Vulcanian explosions by Cassidy, Mike, Cole, Paul.D., Hicks, Kelby E., Varley, Nick R., Peters, Nial, Lerner, Allan H.

“…Vulcanian explosions are one of the most common types of volcanic activity observed at silicic volcanoes. Magma ascent rates are often invoked as being the…”
Get full text

Chemistry, Growth, and Fate of the Unique, Short‐Lived (2019–2020) Water Lake at the Summit of Kīlauea Volcano, Hawaii by Nadeau, P. A., Hurwitz, S., Peek, S., Lerner, A. H., Younger, E. F., Patrick, M. R., Damby, D. E., McCleskey, R. B., Kelly, P. J.

“…Less than a year after the 2018 Kīlauea caldera collapse and eruption, water appeared in newly deepened Halemaʻumaʻu crater. The lake—unprecedented in the…”
Get full text