Search Results - "Lermontova, N. N."

Antihistamine Agent Dimebon As a Novel Neuroprotector and a Cognition Enhancer by BACHURIN, S., BUKATINA, E., LERMONTOVA, N., TKACHENKO, S., AFANASIEV, A., GRIGORIEV, V., GRIGORIEVA, I., IVANOV, YU, SABLIN, S., ZEFIROV, N.

“…: Dimebon, launched earlier in Russia as an antihistamine drug, was evaluated as a representative of a new generation of anti‐Alzheimer's drugs that have two…”
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Wave-Like Dose-Dependence of the Stimulating Effects of Dimebon on Cognition in a Wide Dose Range by Vasilieva, N. A., Shevtsova, E. F., Van’kin, G. I., Lermontova, N. N., Serkova, T. P., Nikolaeva, N. S., Bachurin, S. O.

“…Comparison of the cognition-stimulating effects of Dimebon in a wide dose range revealed a non-monotonic and nontrivial wave-like dose-dependence of its…”
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Dimebon and tacrine inhibit neurotoxic action of beta-amyloid in culture and block L-type Ca(2+) channels by Lermontova, N N, Redkozubov, A E, Shevtsova, E F, Serkova, T P, Kireeva, E G, Bachurin, S O

“…Dimebon, a Russian-made drug, inhibited toxic effects of beta -amyloid on cultured neurons. Excessive accumulation of beta-amyloid in the brain is…”
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Neuroprotective and cognition-enhancing properties of MK-801 flexible analogs. Structure-activity relationships by Bachurin, S, Tkachenko, S, Baskin, I, Lermontova, N, Mukhina, T, Petrova, L, Ustinov, A, Proshin, A, Grigoriev, V, Lukoyanov, N, Palyulin, V, Zefirov, N

“…Neuroprotective and biobehavioral properties of a series of novel open chain MK-801 analogs, as well as their structure-activity relationships have been…”
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N-Acetylserotonin, Melatonin and Their Derivatives Improve Cognition and Protect against β-Amyloid-Induced Neurotoxicity by BACHURIN, S., OXENKRUG, G., LERMONTOVA, N., AFANASIEV, A., BEZNOSKO, B., VANKIN, G., SHEVTZOVA, E., MUKHINA, T., SERKOVA, T.

“…After a single injection of cholinergic neurotoxin ethylcholine aziridinium (AF64A, 3 nmol intracerebroventricularly (i.c.v.)), rats failed to perform the…”
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Dimebon improves learning in animals with experimental Alzheimer's disease by Lermontova, N N, Lukoyanov, N V, Serkova, T P, Lukoyanova, E A, Bachurin, S O

“…Systemic administration of antihistamine drug dimebon improves active avoidance conditioning in rats with chronic partial deprivation of cerebral cholinergic…”
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Comparison of reactive processes in the rat brain elicited by xenotransplantation of nervous tissues of chicken or pulmonate snail by Loseva, Elena V, Vorobyev, Valentin N, Ermakova, Irina V, Lermontova, Nadegda N, Alekseeva, Tiyna G, Zakharov, Igor S, Balaban, Pavel M

“…It is known that a histocompatibility system is not developed to the same extent in lower invertebrates as in vertebrate animals. We assumed that the…”
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The effect of dithiocarbamates on neurotoxic action of 1-methyl-4-phenyl-1,2,3,6 tetrahydropyridine (MPTP) and on mitochondrial respiration chain by Bachurin, S O, Shevtzova, E P, Lermontova, N N, Serkova, T P, Ramsay, R R

“…The neurotoxin MPTP induces in human and in some laboratory animals parkinsonism-like neurological disorder, biochemically characterized by selective and…”
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Comparison of the effect of NT-0409 and antidementia drugs on learning and memory in rats with chronic cerebral cholinergic deficiency by Lermontova, N N, Mukhina, T V, Van'kin, G I, Serkova, T P, Bachurin, S O

“…Systemic oral administration of NT-0409, a new synthetic agonist of AMPA subtype glutamate receptor, to rats with chronic partial AF64A-induced deprivation of…”
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The effects of estrogens on learning in rats with chronic brain cholinergic deficiency in a Morris water test. Identification of the "passive swimming" component by Mukhina, T V, Lermontova, N N, Van'kin, G I, Oettel, M, P'chev, V K, Bachurin, S O

“…Chronic decreases in brain cholinergic functions due to intraventricular administration of the neurotoxin AF64A were accompanied by increases in the latent…”
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Autoantibodies to beta-amyloid and neurotransmitters in patients with Alzheimer's disease and senile dementia of the Alzheimer type by Myagkova, M A, Gavrilova, S I, Lermontova, N N, Kalyn, Y B, Selezneva, N D, Zharikov, G A, Kolykhalov, I V, Abramenko, T V, Serkova, T P, Bachurin, S O

“…The content of autoantibodies to beta-amyloid protein Abeta(1-42), its neurotoxic fragment Abeta(25-35), and neurotransmitters were studied in the blood of…”
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Effects of estrogens on learning of rats with chronic brain cholinergic deficit in Morris water maze by Mukhina, T V, Lermontova, N N, Van'kin, G I, Oettel', M, Pachev, V K, Bachurin, S O

“…A chronic deprivation of brain cholinergic functions in rats caused by intracerebroventricular injection of neurotoxin AF64A increases the escape latency in…”
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Development of neuronal ganglion xenografts from gastropoda in rat brain by Loseva, E V, Vorob'ev, V N, Alekseeva, T G, Ermakova, I V, Zakharov, I S, Lermontova, N N, Balaban, P M

“…Survival of neuronal ganglia from newborn snail (Helix aspera L.) in the brain of adult rats was studied. Snail ganglion survived in the brain of warm-blooded…”
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Effects of 17 beta-estradiol and its isomer 17 alpha-estradiol on learning in rats with chronic cholinergic deficiency in the brain by Lermontova, N N, P'chev, V K, Beznosko, B K, Van'kin, G I, Ivanova, T A, Koroleva, I V, Lukoyanova, E A, Mukhina, T V, Serkova, T P, Bachurin, S O

“…It was shown for the first time that estrogens 17 beta- and 17 alpha-estradiols compensate impaired cognitive functions in rats with partial chronic…”
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Pyridine derivatives: structure-activity relationships causing parkinsonism-like symptoms by Bachurin, S O, Tkachenko, S E, Lermontova, N N

“…In recent years, sufficient evidence has surfaced to implicate low-molecular-weight organic compounds in certain known neurological disorders. At this time,…”
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Content of autoantibodies to bradykinin and beta-amyloid(1-42) as a criterion for biochemical differences between Alzheimer's dementias by Myagkova, M A, Gavrilova, S I, Lermontova, N N, Kalyn, Ya B, Selezneva, N D, Zharikov, G A, Kolykhalov, I V, Abramenko, T V, Serkova, T P, Bachurin, S O

“…We measured serum content of autoantibodies to beta-amyloid protein Abeta(1-42), its neurotoxic fragment Abeta(25-35), vasopressin, bradykinin, thrombin,…”
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Biochemical basis of structural electivity of MPTP-like neurotoxicity by Bachurin, S O, Lermontova, N N, Sablin, S O, Solyakov, L S, Tkachenko, S E

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Versatile computerized system for tracking and analysis of water maze tests by Mukhina, T V, Bachurin, S O, Lermontova, N N, Zefirov, N S

“…A crucial step in the estimation of properties of compounds in behavioral experiments is the quantification and description of the different effects observed…”
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Molecular basis of discrepancies in neurotoxic properties among 1-methyl-4-aryl-1,2,3,6-tetrahydropyridines by Bachurin, S O, Sablin, S O, Lermontova, N N, Solyakov, L S, Dubova, L G, Tkachenko, S E

“…The relationship between structural specificity of the main stages of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) action and the display of…”
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P1-440: Comparative study of Aricept, Memantine and Dimebon effect on memory and cognition in neurotoxin-induced animal model of Alzheimer’s disease by Bachurin, Sergey, Serkova, T., Lermontova, N., Ivanova, T., Beznosko, B., Vankin, G., Koroleva, I., Zefirov, N.

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