Search Results - "Lerer, B."

Differential contribution of genetic variation in multiple brain nicotinic cholinergic receptors to nicotine dependence: recent progress and emerging open questions by Greenbaum, L, Lerer, B

“…Nicotine dependence (ND), a major public health challenge, is a complex, multifactorial behavior, in which both genetic and environmental factors have a role…”
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Differential effects of chronic stress in young-adult and old female mice: cognitive-behavioral manifestations and neurobiological correlates by Lotan, A, Lifschytz, T, Wolf, G, Keller, S, Ben-Ari, H, Tatarsky, P, Pillar, N, Oved, K, Sharabany, J, Merzel, T K, Matsumoto, T, Yamawaki, Y, Mernick, B, Avidan, E, Yamawaki, S, Weller, A, Shomron, N, Lerer, B

“…Stress-related psychopathology is highly prevalent among elderly individuals and is associated with detrimental effects on mood, appetite and cognition…”
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Alterations in the expression of a neurodevelopmental gene exert long-lasting effects on cognitive-emotional phenotypes and functional brain networks: translational evidence from the stress-resilient Ahi1 knockout mouse by Lotan, A, Lifschytz, T, Mernick, B, Lory, O, Levi, E, Ben-Shimol, E, Goelman, G, Lerer, B

“…Many psychiatric disorders are highly heritable and may represent the clinical outcome of early aberrations in the formation of neural networks. The placement…”
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Endocrine approaches to augmenting antidepressants by Lerer, B

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Support for association of HSPG2 with tardive dyskinesia in Caucasian populations by Greenbaum, L, Alkelai, A, Zozulinsky, P, Kohn, Y, Lerer, B

“…Tardive dyskinesia (TD) is a severe adverse effect of chronic antipsychotic drug treatment. In addition to clinical risk factors, TD susceptibility is…”
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Genome-wide linkage scan in a large bipolar disorder sample from the National Institute of Mental Health genetics initiative suggests putative loci for bipolar disorder, psychosis, suicide, and panic disorder by Cheng, R, Juo, S H, Loth, J E, Nee, J, Iossifov, I, Blumenthal, R, Sharpe, L, Kanyas, K, Lerer, B, Lilliston, B, Smith, M, Trautman, K, Gilliam, T C, Endicott, J, Baron, M

“…We conducted a 9-cM genome scan in a large bipolar pedigree sample from the National Institute of Mental Health genetics initiative (1060 individuals from 154…”
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Meeting the challenge of resistant depression by Lerer, B., Symposium Leader

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Environment and vulnerability to major psychiatric illness : a case control study of early parental loss in major depression, bipolar disorder and schizophrenia by AGID, O, SHAPIRA, B, ZISLIN, J, RITSNER, M, HANIN, B, MURAD, H, TROUDART, T, BLOCH, M, HERESCO-LEVY, U, LERER, B

“…The current focus on identifying genes which predispose to psychiatric illness sharpens the need to identify environmental factors which interact with genetic…”
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Amygdalar disconnectivity could underlie stress resilience in the Ahi1 knockout mouse: conclusions from a resting-state functional MRI study by Lotan, A, Lifschytz, T, Lory, O, Goelman, G, Lerer, B

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Convergent lines of evidence support CAMKK2 as a schizophrenia susceptibility gene by Luo, X-j, Li, M, Huang, L, Steinberg, S, Mattheisen, M, Liang, G, Donohoe, G, Shi, Y, Chen, C, Yue, W, Alkelai, A, Lerer, B, Li, Z, Yi, Q, Rietschel, M, Cichon, S, Collier, D A, Tosato, S, Suvisaari, J, Rujescu, Dan, Golimbet, V, Silagadze, T, Durmishi, N, Milovancevic, M P, Stefansson, H, Schulze, T G, Nöthen, M M, Chen, C, Lyne, R, Morris, D W, Gill, M, Corvin, A, Zhang, D, Dong, Q, Moyzis, R K, Stefansson, K, Sigurdsson, E, Hu, F, Su, B, Gan, L

“…Genes that are differentially expressed between schizophrenia patients and healthy controls may have key roles in the pathogenesis of schizophrenia. We…”
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The role of meniscal root pathology and radial meniscal tear in medial meniscal extrusion by LERER, D. B, UMANS, H. R, HU, M. X, JONES, M. H

“…The purpose of our study was twofold: to better understand the relationship between medial meniscal extrusion (MME) and degenerative joint disease (DJD), and…”
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P.2.017 Differential effect of chronic stress on cognition and affect in young and old mice by Tatarskyy, P, Lotan, A, Lifschytz, T, Mernick, B, Wolf, G, Ben-Ari, H, Lerer, B

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Why do young women smoke? I. Direct and interactive effects of environment, psychological characteristics and nicotinic cholinergic receptor genes by GREENBAUM, L, KANYAS, K, KARNI, O, MERBL, Y, OLENDER, T, HOROWITZ, A, YAKIR, A, LANCET, D, BEN-ASHER, E, LERER, B

“…Despite the health hazards, cigarette smoking is disproportionately frequent among young women. A significant contribution of genetic factors to smoking…”
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Excitement and confusion on chromosome 6q: the challenges of neuropsychiatric genetics in microcosm by KOHN, Y, LERER, B

“…The search for genes that are implicated in the pathogenesis of schizophrenia (SCZ), bipolar disorder (BPD) and other complex neuropsychiatric phenotypes has…”
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Genomewide linkage scan of schizophrenia in a large multicenter pedigree sample using single nucleotide polymorphisms by Holmans, P A, Riley, B, Pulver, A E, Owen, M J, Wildenauer, D B, Gejman, P V, Mowry, B J, Laurent, C, Kendler, K S, Nestadt, G, Williams, N M, Schwab, S G, Sanders, A R, Nertney, D, Mallet, J, Wormley, B, Lasseter, V K, O'Donovan, M C, Duan, J, Albus, M, Alexander, M, Godard, S, Ribble, R, Liang, K Y, Norton, N, Maier, W, Papadimitriou, G, Walsh, D, Jay, M, O'Neill, A, Lerer, F B, Dikeos, D, Crowe, R R, Silverman, J M, Levinson, D F

“…A genomewide linkage scan was carried out in eight clinical samples of informative schizophrenia families. After all quality control checks, the analysis of…”
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Role of genetic variants in the CHRNA5–CHRNA3–CHRNB4 cluster in nicotine dependence risk: importance of gene–environment interplay by Greenbaum, L, Rigbi, A, Teltsh, O, Lerer, B

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Why do young women smoke? V. Role of direct and interactive effects of nicotinic cholinergic receptor gene variation on neurocognitive function by Rigbi, A., Kanyas, K., Yakir, A., Greenbaum, L., Pollak, Y., Ben‐Asher, E., Lancet, D., Kertzman, S., Lerer, B.

“…Previous work suggests that young women who smoke cigarettes regularly, or did so in the past, manifest a neurocognitive profile that is characterized by small…”
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Evidence for a putative bipolar disorder locus on 2p13-16 and other potential loci on 4q31, 7q34, 8q13, 9q31, 10q21-24, 13q32, 14q21 and 17q11-12 by Liu, J, Juo, S H, Dewan, A, Grunn, A, Tong, X, Brito, M, Park, N, Loth, J E, Kanyas, K, Lerer, B, Endicott, J, Penchaszadeh, G, Knowles, J A, Ott, J, Gilliam, T C, Baron, M

“…Bipolar disorder (BP) is a severe and common psychiatric disorder characterized by extreme mood swings. Family, twin and adoption studies strongly support a…”
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Effect of triiodothyronine on antidepressant screening tests in mice and on presynaptic 5-HT1A receptors: mediation by thyroid hormone α receptors by Lifschytz, T, Zozulinsky, P, Eitan, R, Landshut, G, Ohayon, S, Lerer, B

“…Although triiodothyronine (T3) is widely used clinically, preclinical support for its antidepressant-like effects is limited, and the mechanisms are unknown…”
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Why do young women smoke? II. Role of traumatic life experience, psychological characteristics and serotonergic genes by LERER, E, KANYAS, K, KARNI, O, EBSTEIN, R. P, LERER, B

“…Cigarette smoking is a complex behavioral phenotype to which environmental, psychological and genetic factors contribute. The purpose of this study was to…”
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