Search Results - "Lerch, Ondřej"

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    Blood Glucose Levels May Exacerbate Executive Function Deficits in Older Adults with Cognitive Impairment by Pappas, Colleen, Small, Brent J, Andel, Ross, Laczó, Jan, Parizkova, Martina, Ondrej, Lerch, Hort, Jakub

    Published in Journal of Alzheimer's disease (01-01-2019)
    “…Identifying protective factors that promote healthy cognitive aging is of importance due to the growing older adult population. Preventing chronic…”
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    Journal Article
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    The effect of Alzheimer's disease on spatial navigation strategies by Parizkova, Martina, Lerch, Ondrej, Moffat, Scott Douglas, Andel, Ross, Mazancova, Adela Fendrych, Nedelska, Zuzana, Vyhnalek, Martin, Hort, Jakub, Laczó, Jan

    Published in Neurobiology of aging (01-04-2018)
    “…Hippocampal and basal forebrain (BF) atrophy is associated with allocentric navigation impairment in Alzheimer's disease (AD) and may lead to recruitment of…”
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    Spatial Pattern Separation Testing Differentiates Alzheimer's Disease Biomarker-Positive and Biomarker-Negative Older Adults With Amnestic Mild Cognitive Impairment by Laczó, Martina, Lerch, Ondrej, Martinkovic, Lukas, Kalinova, Jana, Markova, Hana, Vyhnalek, Martin, Hort, Jakub, Laczó, Jan

    Published in Frontiers in aging neuroscience (26-11-2021)
    “…The hippocampus, entorhinal cortex (EC), and basal forebrain (BF) are among the earliest regions affected by Alzheimer's disease (AD) pathology. They play an…”
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    Longitudinal progression of choroid plexus enlargement is associated with female sex, cognitive decline and ApoE E4 homozygote status by Novakova Martinkova, Julie, Ferretti, Maria Teresa, Ferrari, Alberto, Lerch, Ondrej, Matuskova, Veronika, Secnik, Juraj, Hort, Jakub

    Published in Frontiers in psychiatry (2023)
    “…Choroid plexus (CP)-related mechanisms have been implicated in the pathogenesis of neurodegenerative diseases, including Alzheimer's disease. In this pilot…”
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    Homocysteine and Real-Space Navigation Performance among Non-Demented Older Adults by Pařízková, Martina, Andel, Ross, Lerch, Ondřej, Marková, Hana, Gažová, Ivana, Vyhnálek, Martin, Hort, Jakub, Laczó, Jan

    Published in Journal of Alzheimer's disease (01-01-2017)
    “…High plasma homocysteine (Hcy) level is related to higher risk of Alzheimer's disease (AD) and lower cognitive performance in older adults. To assess the…”
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    Predicting progression from subjective cognitive decline to mild cognitive impairment or dementia based on brain atrophy patterns by Lerch, Ondrej, Ferreira, Daniel, Stomrud, Erik, van Westen, Danielle, Tideman, Pontus, Palmqvist, Sebastian, Mattsson-Carlgren, Niklas, Hort, Jakub, Hansson, Oskar, Westman, Eric

    Published in Alzheimer's research & therapy (05-07-2024)
    “…Alzheimer's disease (AD) is a progressive neurodegenerative disorder where pathophysiological changes begin decades before the onset of clinical symptoms…”
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    Spatial navigation questionnaires as a supportive diagnostic tool in early Alzheimer’s disease by Laczó, Martina, Svatkova, Radka, Lerch, Ondrej, Martinkovic, Lukas, Zuntychova, Terezie, Nedelska, Zuzana, Horakova, Hana, Vyhnalek, Martin, Hort, Jakub, Laczó, Jan

    Published in iScience (21-06-2024)
    “…Impaired spatial navigation is early marker of Alzheimer’s disease (AD). We examined ability of self- and informant-reported navigation questionnaires to…”
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    APOEɛ4 Allele Moderates the Association Between Basal Forebrain Nuclei Volumes and Allocentric Navigation in Older Adults Without Dementia by Lerch, Ondřej, Laczó, Martina, Vyhnálek, Martin, Nedelská, Zuzana, Hort, Jakub, Laczó, Jan

    Published in Journal of Alzheimer's disease (2022)
    “…Cholinergic deficit and medial temporal lobe (MTL) atrophy are hallmarks of Alzheimer's disease (AD) leading to early allocentric spatial navigation (aSN)…”
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