Search Results - "Lerch, Ondřej"
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Blood Glucose Levels May Exacerbate Executive Function Deficits in Older Adults with Cognitive Impairment
Published in Journal of Alzheimer's disease (01-01-2019)“…Identifying protective factors that promote healthy cognitive aging is of importance due to the growing older adult population. Preventing chronic…”
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The effect of Alzheimer's disease on spatial navigation strategies
Published in Neurobiology of aging (01-04-2018)“…Hippocampal and basal forebrain (BF) atrophy is associated with allocentric navigation impairment in Alzheimer's disease (AD) and may lead to recruitment of…”
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Spatial Pattern Separation Testing Differentiates Alzheimer's Disease Biomarker-Positive and Biomarker-Negative Older Adults With Amnestic Mild Cognitive Impairment
Published in Frontiers in aging neuroscience (26-11-2021)“…The hippocampus, entorhinal cortex (EC), and basal forebrain (BF) are among the earliest regions affected by Alzheimer's disease (AD) pathology. They play an…”
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Longitudinal progression of choroid plexus enlargement is associated with female sex, cognitive decline and ApoE E4 homozygote status
Published in Frontiers in psychiatry (2023)“…Choroid plexus (CP)-related mechanisms have been implicated in the pathogenesis of neurodegenerative diseases, including Alzheimer's disease. In this pilot…”
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Homocysteine and Real-Space Navigation Performance among Non-Demented Older Adults
Published in Journal of Alzheimer's disease (01-01-2017)“…High plasma homocysteine (Hcy) level is related to higher risk of Alzheimer's disease (AD) and lower cognitive performance in older adults. To assess the…”
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Predicting progression from subjective cognitive decline to mild cognitive impairment or dementia based on brain atrophy patterns
Published in Alzheimer's research & therapy (05-07-2024)“…Alzheimer's disease (AD) is a progressive neurodegenerative disorder where pathophysiological changes begin decades before the onset of clinical symptoms…”
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Different Profiles of Spatial Navigation Deficits In Alzheimer’s Disease Biomarker-Positive Versus Biomarker-Negative Older Adults With Amnestic Mild Cognitive Impairment
Published in Frontiers in aging neuroscience (02-06-2022)“…Background Spatial navigation impairment is a promising cognitive marker of Alzheimer’s disease (AD) that can reflect the underlying pathology. Objectives We…”
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Spatial navigation questionnaires as a supportive diagnostic tool in early Alzheimer’s disease
Published in iScience (21-06-2024)“…Impaired spatial navigation is early marker of Alzheimer’s disease (AD). We examined ability of self- and informant-reported navigation questionnaires to…”
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IMPAIRMENT OF MEDIAL SEPTAL PROJECTIONS CONTRIBUTES TO HIPPOCAMPAL ATROPHY IN SUBJECTS AT RISK OF ALZHEIMER’S DISEASE
Published in Alzheimer's & dementia (01-07-2018)Get full text
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O4‐04‐04: IMPAIRMENT OF MEDIAL SEPTAL PROJECTIONS CONTRIBUTES TO HIPPOCAMPAL ATROPHY IN SUBJECTS AT RISK OF ALZHEIMER'S DISEASE
Published in Alzheimer's & dementia (01-07-2018)Get full text
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APOEɛ4 Allele Moderates the Association Between Basal Forebrain Nuclei Volumes and Allocentric Navigation in Older Adults Without Dementia
Published in Journal of Alzheimer's disease (2022)“…Cholinergic deficit and medial temporal lobe (MTL) atrophy are hallmarks of Alzheimer's disease (AD) leading to early allocentric spatial navigation (aSN)…”
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VASCULAR RISK FACTORS AND BASAL FOREBRAIN ATROPHY IN SUBJECTS AT RISK OF ALZHEIMER’S DISEASE
Published in Alzheimer's & dementia (01-07-2017)Get full text
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P1‐529: IMPACT OF BDNF AND APOE POLYMORPHISM ON COGNITIVE PERFORMANCE IN PATIENTS AT INCREASED RISK OF DEVELOPING ALZHEIMER'S DISEASE
Published in Alzheimer's & dementia (01-07-2018)Get full text
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IMPACT OF BDNF AND APOE POLYMORPHISM ON COGNITIVE PERFORMANCE IN PATIENTS AT INCREASED RISK OF DEVELOPING ALZHEIMER'S DISEASE
Published in Alzheimer's & dementia (01-07-2018)Get full text
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EGOCENTRIC SPATIAL NAVIGATION IMPAIRMENT IS MORE PRONOUNCED IN AMYLOID POSITIVE MCI PATIENTS: PILOT DATA FROM THE CZECH BRAIN AGEING STUDY
Published in Alzheimer's & dementia (01-07-2018)Get full text
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SPECIFIC DIFFERENCES IN SPATIAL NAVIGATION PERFORMANCE IN NEURODEGENERATIVE DEMENTIAS
Published in Alzheimer's & dementia (01-07-2016)Get full text
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P2‐210: Specific Differences in Spatial Navigation Performance in Neurodegenerative Dementias
Published in Alzheimer's & dementia (01-07-2016)Get full text
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