Search Results - "Leppik, I.E."
-
1
The effect of topiramate plasma concentration on linguistic behavior, verbal recall and working memory
Published in Epilepsy & behavior (01-07-2012)“…Abstract This is the first study of the effect of topiramate on linguistic behavior and verbal recall using a computational linguistics system for automated…”
Get full text
Journal Article -
2
Double‐Masked, Placebo‐Controlled Study of Intravenous Levetiracetam for the Treatment of Status Epilepticus and Acute Repetitive Seizures in Dogs
Published in Journal of veterinary internal medicine (01-03-2012)“…Background Status epilepticus (SE) and acute repetitive seizures (ARS) are common canine neurologic emergencies. No evidence‐based studies are available to…”
Get full text
Journal Article -
3
Incidence and risk factors in sudden unexpected death in epilepsy : A prospective cohort study
Published in Neurology (27-02-2001)“…To determine incidence of and risk factors for sudden unexpected death in epilepsy (SUDEP). Three epilepsy centers enrolled 4,578 patients and prospectively…”
Get full text
Journal Article -
4
Zonisamide discontinuation due to psychiatric and cognitive adverse events: A case-control study
Published in Neurology (10-08-2010)“…Zonisamide (ZNS) is an antiepileptic drug (AED) that has been associated with psychiatric adverse events (PAE) and cognitive adverse events (CAE); controlled…”
Get full text
Journal Article -
5
Intramuscular, intravenous and oral levetiracetam in dogs: safety and pharmacokinetics
Published in Journal of veterinary pharmacology and therapeutics (01-06-2008)“…Intravenous (IV) levetiracetam (LEV) is available for humans for bridge therapy when the oral route is unavailable. We investigated the safety and…”
Get full text
Journal Article -
6
Characterization of the Time Course of Carbamazepine Deinduction by an Enzyme Turnover Model
Published in Clinical pharmacokinetics (01-01-2009)“…Background and objective: Carbamazepine is a potent inducer of drug metabolizing enzymes, which results in a number of clinically significant drug-drug…”
Get full text
Journal Article -
7
Critical re-evaluation of previous preclinical strategies for the discovery and the development of new antiepileptic drugs
Published in Epilepsy research (01-06-2002)“…During the last decade, several new antiepileptic drugs (AEDs) have been introduced in Europe, the United States, or other parts of the world. Although the…”
Get full text
Journal Article Conference Proceeding -
8
A double-blind, placebo-controlled study of remacemide hydrochloride in patients with refractory epilepsy following pre-surgical assessment
Published in Seizure (London, England) (01-09-2002)“…This multicentre, randomised, double-blind, placebo-controlled, parallel-group study investigated the efficacy, safety and pharmacokinetics of remacemide…”
Get full text
Journal Article -
9
Efficacy and safety of zonisamide: results of a multicenter study
Published in Epilepsy research (01-02-1993)“…The safety and efficacy of zonisamide (ZNS), a new antiepileptic drug, was tested in 167 adult participants who entered a historical-controlled 16-week open…”
Get more information
Journal Article -
10
Intramuscular fosphenytoin (Cerebyx®) in patients requiring a loading dose of phenytoin
Published in Epilepsy research (01-10-1997)“…Fosphenytoin (Cerebyx®), is a water soluble prodrug that is rapidly and completely converted to phenytoin. This study reports the injection-site tolerance and…”
Get full text
Journal Article -
11
Familial cerebral cavernous angioma: Clinical analysis of a family and phenotypic classification
Published in Epilepsy research (01-05-1995)“…Only a few large families with cerebral cavernous angiomas (CCA) have been reported. We studied 47 members of a four-generation kindred with familial CCA…”
Get full text
Journal Article -
12
Should single epileptic seizures be treated?
Published in European neurology (1994)Get more information
Journal Article -
13
Machine detection of spike-wave activity in the EEG and its accuracy compared with visual interpretation
Published in Electroencephalography and clinical neurophysiology (01-01-1982)“…Machine detection of epileptiform activity in the EEG is useful in seizure monitoring because of its inherent consistency and the rapid data reduction it can…”
Get more information
Journal Article