Search Results - "Lepper, Philipp M"
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Position Paper for the State-of-the-Art Application of Respiratory Support in Patients with COVID-19
Published in Respiration (01-07-2020)“…Against the background of the pandemic caused by infection with the SARS-CoV-2 virus, the German Respiratory Society has appointed experts to develop therapy…”
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Daratumumab for a Patient With Refractory Antineutrophil Cytoplasmatic Antibody-Associated Vasculitis
Published in JAMA internal medicine (01-06-2023)Get more information
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Two single lung transplantations from one donor: lung twinning in the LAS era
Published in Respiratory research (18-03-2024)“…The implementation of the Lung Allocation Score (LAS) in the Eurotransplant international collaborative framework decreased waiting list mortality, but organ…”
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Comparison of isoflurane and propofol sedation in critically ill COVID-19 patients—a retrospective chart review
Published in Journal of anesthesia (01-10-2021)“…Purpose In this retrospective study, we compared inhaled sedation with isoflurane to intravenous propofol in invasively ventilated COVID-19 patients with ARDS…”
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Glycyrrhizin through liquorice intake modulates ACE2 and HMGB1 levels—A pilot study in healthy individuals with implications for COVID-19 and ARDS
Published in PloS one (17-10-2022)“…Background Glycyrrhizin, an active component of liquorice root extract, exhibits antiviral and immunomodulatory properties by direct inhibition of the…”
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Symmetric dimethylarginine, high-density lipoproteins and cardiovascular disease
Published in European heart journal (21-05-2017)“…The vascular effects of high-density lipoproteins (HDL) differ under certain clinical conditions. The composition of HDL is modified in patients with chronic…”
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Exposure of patients to di(2-ethylhexy)phthalate (DEHP) and its metabolite MEHP during extracorporeal membrane oxygenation (ECMO) therapy
Published in PloS one (01-01-2020)“…The plasticizer di(2-ethylhexyl)phthalate (DEHP) is often used for PVC medical devices, that are also largely used for intensive care medical treatments, like…”
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Mechanical thrombectomy in intermediate- and high-risk acute pulmonary embolism: hemodynamic outcomes at three months
Published in Respiratory research (25-10-2023)“…Abstract Background Mechanical thrombectomy has been shown to reduce thrombus burden and pulmonary artery pressure (PAP) and to improve right ventricular (RV)…”
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Survival after extracorporeal membrane oxygenation in severe COVID-19 ARDS: results from an international multicenter registry
Published in Critical care (London, England) (01-03-2021)“…At the participating centers, all patients with reverse transcriptase polymerase chain reaction (rtPCR) positive testing for SARS-CoV-2, who received V-V ECMO…”
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High levels of SARS-CoV-2-specific T cells with restricted functionality in severe courses of COVID-19
Published in JCI insight (15-10-2020)“…BACKGROUNDPatients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) differ in the severity of disease. We hypothesized that…”
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FOXO transcription factors regulate innate immune mechanisms in respiratory epithelial cells
Published in The Journal of immunology (1950) (15-02-2013)“…Bacterial pathogens are a leading cause of lung infections and contribute to acute exacerbations in patients with chronic respiratory diseases. The innate…”
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TNF-related apoptosis-inducing ligand, interferon gamma-induced protein 10, and C-reactive protein in predicting the progression of SARS-CoV-2 infection: a prospective cohort study
Published in International journal of infectious diseases (01-09-2022)“…•Biomarkers TNF-related apoptosis-inducing ligand (TRAIL), interferon gamma-induced protein 10 (IP-10), and C-reactive protein (CRP) are correlated with…”
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Pulmonary nocardiosis in Western Europe—Clinical evaluation of 43 patients and population-based estimates of hospitalization rates
Published in International journal of infectious diseases (01-04-2019)“…Pulmonary nocardiosis (PN) is an uncommon but potentially life-threatening infection. Most of our knowledge on PN is derived from case reports and small case…”
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Comparison of immersive and non-immersive virtual reality videos as substitute for in-hospital teaching during coronavirus lockdown: a survey with graduate medical students in Germany
Published in Medical education online (31-12-2022)“…As a consequence of the continued Covid-19 lockdown in Germany, in-hospital teaching for medical students was impossible. While lectures and other theoretical…”
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Cryoprobe biopsy increases the diagnostic yield in endobronchial tumor lesions
Published in The Journal of thoracic and cardiovascular surgery (01-08-2010)“…Objective Forceps biopsy is the standard method to obtain specimens in endoscopically visible lesions. It is common to combine forceps biopsy with cytology…”
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High-dose methylprednisolone pulse therapy during refractory COVID-19 acute respiratory distress syndrome: a retrospective observational study
Published in BMC pulmonary medicine (03-10-2023)“…Current COVID-19 guidelines recommend the early use of systemic corticoids for COVID-19 acute respiratory distress syndrome (ARDS). It remains unknown if…”
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Ecology of Pseudomonas aeruginosa in the intensive care unit and the evolving role of water outlets as a reservoir of the organism
Published in American journal of infection control (01-06-2005)“…In spite of the significant changes in the spectrum of organisms causing intensive care unit (ICU)-associated infections, Pseudomonas aeruginosa has held a…”
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Mechanical ventilation in early COVID-19 ARDS
Published in EClinicalMedicine (01-11-2020)Get full text
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Improving Outcomes in Bridge-to-Transplant: Extended Extracorporeal Membrane Oxygenation Support to Obtain Optimal Donor Lungs for Marginal Recipients
Published in ASAIO journal (1992) (01-07-2019)“…The use of extracorporeal membrane oxygenation (ECMO) as bridge-to-lung transplantation has been discussed controversially because of discouraging results. We…”
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IL-17C is a mediator of respiratory epithelial innate immune response
Published in American journal of respiratory cell and molecular biology (01-04-2013)“…The IL-17 family of cytokines consists of at least six members (IL-17A to -F). IL-17 directly activates epithelial cells leading to the expression of…”
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