Search Results - "Lepper, Philipp M"

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    Position Paper for the State-of-the-Art Application of Respiratory Support in Patients with COVID-19 by Pfeifer, Michael, Ewig, Santiago, Voshaar, Thomas, Randerath, Winfried Johannes, Bauer, Torsten, Geiseler, Jens, Dellweg, Dominic, Westhoff, Michael, Windisch, Wolfram, Schönhofer, Bernd, Kluge, Stefan, Lepper, Philipp M

    Published in Respiration (01-07-2020)
    “…Against the background of the pandemic caused by infection with the SARS-CoV-2 virus, the German Respiratory Society has appointed experts to develop therapy…”
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    Journal Article
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    Two single lung transplantations from one donor: lung twinning in the LAS era by Langer, Frank, Lepper, Philipp M, Weingard, Bettina, Aliyev, Parviz, Bals, Robert, Wilkens, Heinrike

    Published in Respiratory research (18-03-2024)
    “…The implementation of the Lung Allocation Score (LAS) in the Eurotransplant international collaborative framework decreased waiting list mortality, but organ…”
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    Comparison of isoflurane and propofol sedation in critically ill COVID-19 patients—a retrospective chart review by Kermad, Azzeddine, Speltz, Jacques, Danziger, Guy, Mertke, Thilo, Bals, Robert, Volk, Thomas, Lepper, Philipp M., Meiser, Andreas

    Published in Journal of anesthesia (01-10-2021)
    “…Purpose In this retrospective study, we compared inhaled sedation with isoflurane to intravenous propofol in invasively ventilated COVID-19 patients with ARDS…”
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    Glycyrrhizin through liquorice intake modulates ACE2 and HMGB1 levels—A pilot study in healthy individuals with implications for COVID-19 and ARDS by Buder, Felix, Selejan, Simina-Ramona, Hohl, Mathias, Kindermann, Michael, Herr, Christian, Lepper, Philipp M, Bals, Robert, Salzberger, Bernd, Mahfoud, Felix, Böhm, Michael

    Published in PloS one (17-10-2022)
    “…Background Glycyrrhizin, an active component of liquorice root extract, exhibits antiviral and immunomodulatory properties by direct inhibition of the…”
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    Exposure of patients to di(2-ethylhexy)phthalate (DEHP) and its metabolite MEHP during extracorporeal membrane oxygenation (ECMO) therapy by Kaestner, Franziska, Seiler, Frederik, Rapp, Daniel, Eckert, Elisabeth, Müller, Johannes, Metz, Carlos, Bals, Robert, Drexler, Hans, Lepper, Philipp M, Göen, Thomas

    Published in PloS one (01-01-2020)
    “…The plasticizer di(2-ethylhexyl)phthalate (DEHP) is often used for PVC medical devices, that are also largely used for intensive care medical treatments, like…”
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    Mechanical thrombectomy in intermediate- and high-risk acute pulmonary embolism: hemodynamic outcomes at three months by Lauder, Lucas, Pérez Navarro, Patricia, Götzinger, Felix, Ewen, Sebastian, Al Ghorani, Hussam, Haring, Bernhard, Lepper, Philipp M, Kulenthiran, Saarraaken, Böhm, Michael, Link, Andreas, Scheller, Bruno, Mahfoud, Felix

    Published in Respiratory research (25-10-2023)
    “…Abstract Background Mechanical thrombectomy has been shown to reduce thrombus burden and pulmonary artery pressure (PAP) and to improve right ventricular (RV)…”
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    Survival after extracorporeal membrane oxygenation in severe COVID-19 ARDS: results from an international multicenter registry by Supady, Alexander, Taccone, Fabio Silvio, Lepper, Philipp M, Ziegeler, Stephan, Staudacher, Dawid L

    Published in Critical care (London, England) (01-03-2021)
    “…At the participating centers, all patients with reverse transcriptase polymerase chain reaction (rtPCR) positive testing for SARS-CoV-2, who received V-V ECMO…”
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    High levels of SARS-CoV-2-specific T cells with restricted functionality in severe courses of COVID-19 by Schub, David, Klemis, Verena, Schneitler, Sophie, Mihm, Janine, Lepper, Philipp M, Wilkens, Heinrike, Bals, Robert, Eichler, Hermann, Gärtner, Barbara C, Becker, Sören L, Sester, Urban, Sester, Martina, Schmidt, Tina

    Published in JCI insight (15-10-2020)
    “…BACKGROUNDPatients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) differ in the severity of disease. We hypothesized that…”
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    FOXO transcription factors regulate innate immune mechanisms in respiratory epithelial cells by Seiler, Frederik, Hellberg, Jan, Lepper, Philipp M, Kamyschnikow, Andreas, Herr, Christian, Bischoff, Markus, Langer, Frank, Schäfers, Hans-Joachim, Lammert, Frank, Menger, Michael D, Bals, Robert, Beisswenger, Christoph

    Published in The Journal of immunology (1950) (15-02-2013)
    “…Bacterial pathogens are a leading cause of lung infections and contribute to acute exacerbations in patients with chronic respiratory diseases. The innate…”
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    Cryoprobe biopsy increases the diagnostic yield in endobronchial tumor lesions by Schumann, Christian, MD, Hetzel, Jürgen, MD, Babiak, Alexander J., MD, Merk, Tobias, MD, Wibmer, Thomas, MD, Möller, Peter, MD, PhD, Lepper, Philipp M., MD, Hetzel, Martin, MD

    “…Objective Forceps biopsy is the standard method to obtain specimens in endoscopically visible lesions. It is common to combine forceps biopsy with cytology…”
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    High-dose methylprednisolone pulse therapy during refractory COVID-19 acute respiratory distress syndrome: a retrospective observational study by Zeiner, Carsten, Schröder, Malte, Metzner, Selina, Herrmann, Johannes, Notz, Quirin, Hottenrott, Sebastian, Röder, Daniel, Meybohm, Patrick, Lepper, Philipp M, Lotz, Christopher

    Published in BMC pulmonary medicine (03-10-2023)
    “…Current COVID-19 guidelines recommend the early use of systemic corticoids for COVID-19 acute respiratory distress syndrome (ARDS). It remains unknown if…”
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    Ecology of Pseudomonas aeruginosa in the intensive care unit and the evolving role of water outlets as a reservoir of the organism by Trautmann, Matthias, Lepper, Philipp M., Haller, Mathias

    Published in American journal of infection control (01-06-2005)
    “…In spite of the significant changes in the spectrum of organisms causing intensive care unit (ICU)-associated infections, Pseudomonas aeruginosa has held a…”
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    Improving Outcomes in Bridge-to-Transplant: Extended Extracorporeal Membrane Oxygenation Support to Obtain Optimal Donor Lungs for Marginal Recipients by Langer, Frank, Aliyev, Parviz, Schäfers, Hans-Joachim, Trudzinski, Franziska C, Seiler, Frederik, Bals, Robert, Wilkens, Heinrike, Lepper, Philipp M

    Published in ASAIO journal (1992) (01-07-2019)
    “…The use of extracorporeal membrane oxygenation (ECMO) as bridge-to-lung transplantation has been discussed controversially because of discouraging results. We…”
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    IL-17C is a mediator of respiratory epithelial innate immune response by Pfeifer, Philipp, Voss, Meike, Wonnenberg, Bodo, Hellberg, Jan, Seiler, Frederik, Lepper, Philipp M, Bischoff, Markus, Langer, Frank, Schäfers, Hans-Joachim, Menger, Michael D, Bals, Robert, Beisswenger, Christoph

    “…The IL-17 family of cytokines consists of at least six members (IL-17A to -F). IL-17 directly activates epithelial cells leading to the expression of…”
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