Search Results - "Leppänen, Luukas"

S327 phosphorylation of the presynaptic protein SEPTIN5 increases in the early stages of neurofibrillary pathology and alters the functionality of SEPTIN5 by Ferreira, Catarina B., Marttinen, Mikael, Coelho, Joana E., Paldanius, Kaisa M.A., Takalo, Mari, Mäkinen, Petra, Leppänen, Luukas, Miranda-Lourenço, Catarina, Fonseca-Gomes, João, Tanqueiro, Sara R., Vaz, Sandra H., Belo, Rita F., Sebastião, Ana Maria, Leinonen, Ville, Soininen, Hilkka, Pike, Ian, Haapasalo, Annakaisa, Lopes, Luísa V., de Mendonça, Alexandre, Diógenes, Maria José, Hiltunen, Mikko

“…Alzheimer's disease (AD) is the most common form of dementia, which is neuropathologically characterized by extracellular senile plaques containing amyloid-β…”
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Diabetic phenotype in mouse and humans reduces the number of microglia around β-amyloid plaques by Natunen, Teemu, Martiskainen, Henna, Marttinen, Mikael, Gabbouj, Sami, Koivisto, Hennariikka, Kemppainen, Susanna, Kaipainen, Satu, Takalo, Mari, Svobodová, Helena, Leppänen, Luukas, Kemiläinen, Benjam, Ryhänen, Simo, Kuulasmaa, Teemu, Rahunen, Eija, Juutinen, Sisko, Mäkinen, Petra, Miettinen, Pasi, Rauramaa, Tuomas, Pihlajamäki, Jussi, Haapasalo, Annakaisa, Leinonen, Ville, Tanila, Heikki, Hiltunen, Mikko

“…Background Alzheimer’s disease (AD) is the most common neurodegenerative disease and type 2 diabetes (T2D) plays an important role in conferring the risk for…”
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Presynaptic vesicle protein SEPTIN5 regulates the degradation of APP C-Terminal fragments and the levels of Aβ by Marttinen, Mikael, Ferreira, Catarina B., Paldanius, Kaisa M. A., Takalo, Mari, Natunen, Teemu, Mäkinen, Petra, Leppänen, Luukas, Leinonen, Ville, Tanigaki, Kenji, Kang, Gina, Hiroi, Noboru, Soininen, Hilkka, Rilla, Kirsi, Haapasalo, Annakaisa, Hiltunen, Mikko

“…© 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative…”
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Diabetic phenotype in mouse and humans reduces the number of microglia around [beta]-amyloid plaques by Natunen, Teemu, Ma, Marttinen, Mikael, Gabbouj, Sami, Koivisto, Hennariikka, Kemppainen, Susanna, Kaipainen, Satu, Takalo, Mari, Svobodová, Helena, Leppänen, Luukas, Kemiläinen, Benjam, Ryhänen, Simo, Kuulasmaa, Teemu, Rahunen, Eija, Juutinen, Sisko, Mäkinen, Petra, Miettinen, Pasi, Rauramaa, Tuomas, Pihlajamäki, Jussi, Haapasalo, Annakaisa, Leinonen, Ville, Tanila, Heikki, Hiltunen, Mikko

“…Background Alzheimer's disease (AD) is the most common neurodegenerative disease and type 2 diabetes (T2D) plays an important role in conferring the risk for…”
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Presynaptic Vesicle Protein SEPTIN5 Regulates the Degradation of APP C-Terminal Fragments and the Levels of A[beta] by Marttinen, Mikael, Ferreira, Catarina B, Paldanius, Kaisa M.A, Takalo, Mari, Natunen, Teemu, Makinen, Petra, Leppanen, Luukas, Leinonen, Ville, Tanigaki, Kenji, Kang, Gina, Hiroi, Noboru, Soininen, Hilkka, Rilla, Kirsi, Haapasalo, Annakaisa, Hiltunen, Mikko

“…Alzheimer's disease (AD) is a neurodegenerative disease characterized by aberrant amyloid-[beta] (A [beta] and hyperphosphorylated tau aggregation. We have…”
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