Search Results - "Lepin, E. J."

Phosphorylated S6 Ribosomal Protein: A Novel Biomarker of Antibody‐Mediated Rejection in Heart Allografts by Lepin, E. J., Zhang, Q., Zhang, X., Jindra, P. T., Hong, L. S., Ayele, P., Peralta, M. V. P., Gjertson, D. W., Kobashigawa, J. A., Wallace, W. D., Fishbein, M. C., Reed, E. F.

“…We tested the hypothesis that phosphorylation of S6 ribosomal protein (S6RP), a downstream target of the PI3K/Akt/mTOR pathway, is a biomarker of…”
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HLA class I signal transduction is dependent on Rho GTPase and ROK by Lepin, Eric J., Jin, Yi-Ping, Barwe, Sonali P., Rozengurt, Enrique, Reed, Elaine F.

“…Chronic rejection is the major limitation to long-term allograft survival. HLA class I signaling pathways have been implicated in this process because ligation…”
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Functional characterization of HLA‐F and binding of HLA‐F tetramers to ILT2 and ILT4 receptors by Lepin, Eric J. M., Bastin, Judy M., Allan, David S. J., Roncador, Giovanna, Braud, Veronique M., Mason, David Y., Merwe, P. Anton van der, McMichael, Andrew J., Bell, John I., Powis, Stephen H., O'Callaghan, Christopher A.

“…HLA‐F is a human non‐classical MHC molecule. Recombinant HLA‐F heavy chain was refolded with β2‐microglobulin to form a stable complex. This complex was used…”
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Tetrameric complexes of HLA-E, HLA-F, and HLA-G by Allan, David S.J, Lepin, Eric J.M, Braud, Veronique M, O'Callaghan, Christopher A, McMichael, Andrew J

“…HLA-E, HLA-F, and HLA-G are human nonclassical MHC class Ib molecules. To study the function and identify potential ligands of these molecules, we constructed…”
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Anti-HLA class I antibodies activate endothelial cells and promote chronic rejection by JIN, Yi-Ping, JINDRA, Peter T, KE WEI GONG, LEPIN, Eric J, REED, Elaine F

“…Transplant recipients exhibiting a humoral immune response to the allograft demonstrate lower graft survival and increased risk for the development of chronic…”
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