Search Results - "Lepeu, Gerard"

Chromosomal Abnormalities Are Major Prognostic Factors in Elderly Patients With Multiple Myeloma: The Intergroupe Francophone du Myélome Experience by AVET-LOISEAU, Hervé, HULIN, Cyrille, CAILLOT, Denis, WETTERWALD, Marc, PEGOURIE, Brigitte, LEPEU, Gerard, CORRONT, Bernadette, KARLIN, Lionel, STOPPA, Anne-Marie, FUZIBET, Jean-Gabriel, DELBREL, Xavier, GUILHOT, Francois, CAMPION, Loic, KOLB, Brigitte, DECAUX, Olivier, LAMY, Thierry, GARDERET, Laurent, ALLANGBA, Olivier, LIFERMANN, Francois, ANGLARET, Bruno, MOREAU, Philippe, HAROUSSEAU, Jean-Luc, FACON, Thierry, RODON, Philippe, MARIT, Gerald, ATTAL, Michel, ROYER, Bruno, DIB, Mamoun, VOILLAT, Laurent, BOUSCARY, Didier

“…Chromosomal abnormalities, especially t(4;14) and del(17p), are major prognostic factors in patients with multiple myeloma (MM). However, this has been…”
Get full text

Long-term outcome of patients in the LNH-98.5 trial, the first randomized study comparing rituximab-CHOP to standard CHOP chemotherapy in DLBCL patients: a study by the Groupe d'Etudes des Lymphomes de l'Adulte by Coiffier, Bertrand, Thieblemont, Catherine, Van Den Neste, Eric, Lepeu, Gérard, Plantier, Isabelle, Castaigne, Sylvie, Lefort, Sophie, Marit, Gérald, Macro, Margaret, Sebban, Catherine, Belhadj, Karim, Bordessoule, Dominique, Fermé, Christophe, Tilly, Hervé

“…We report the outcome of patients included in the LNH-98.5 study, which compared cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) to rituximab…”
Get full text

Attenuated immunochemotherapy regimen (R-miniCHOP) in elderly patients older than 80 years with diffuse large B-cell lymphoma: a multicentre, single-arm, phase 2 trial by Peyrade, Frédéric, Dr, Jardin, Fabrice, Prof, Thieblemont, Catherine, Prof, Thyss, Antoine, Prof, Emile, Jean-François, Prof, Castaigne, Sylvie, Prof, Coiffier, Bertrand, Prof, Haioun, Corinne, Prof, Bologna, Serge, MD, Fitoussi, Olivier, MD, Lepeu, Gérard, MD, Fruchart, Christophe, MD, Bordessoule, Dominique, MD, Blanc, Michel, MD, Delarue, Richard, Prof, Janvier, Maud, MD, Salles, Bruno, MD, André, Marc, MD, Fournier, Marion, Gaulard, Philippe, Prof, Tilly, Hervé, Prof

“…Summary Background Diffuse large B-cell lymphoma is a common cancer in elderly patients. Although treatment has been standardised in younger patients, no…”
Get full text

Bortezomib plus dexamethasone versus reduced-dose bortezomib, thalidomide plus dexamethasone as induction treatment before autologous stem cell transplantation in newly diagnosed multiple myeloma by Moreau, Philippe, Avet-Loiseau, Herve, Facon, Thierry, Attal, Michel, Tiab, Mourad, Hulin, Cyrille, Doyen, Chantal, Garderet, Laurent, Randriamalala, Edouard, Araujo, Carla, Lepeu, Gérard, Marit, Gerald, Caillot, Denis, Escoffre, Martine, Lioure, Bruno, Benboubker, Lotfi, Pégourié, Brigitte, Kolb, Brigitte, Stoppa, Anne Marie, Fuzibet, Jean-Gabriel, Decaux, Olivier, Dib, Mamoun, Berthou, Christian, Chaleteix, Carine, Sebban, Catherine, Traullé, Catherine, Fontan, Jean, Wetterwald, Marc, Lenain, Pascal, Mathiot, Claire, Harousseau, Jean-Luc

“…The Intergroupe Francophone du Myelome conducted a randomized trial to compare bortezomib-dexamethasone (VD) as induction before high-dose therapy (HDT) and…”
Get full text

Radioimmunotherapy in relapsed follicular lymphoma previously treated by autologous bone marrow transplant: a report of eight new cases and literature review by Peyrade, Frederic, Triby, Caroline, Slama, Bohane, Fontana, Xavier, Gressin, Remy, Broglia, Jean-Marc, Lepeu, GéRard, Carrier, Patricia, Peyrottes, Isabelle, Darcourt, Jacques, Bondiau, Pierre-Yves, Thyss, Antoine

“…Multicenter, retrospective study of standard-dose RIT in eight heavily pre-treated patients with CD20-positive follicular lymphoma who had relapsed after…”
Get full text

Carfilzomib Weekly plus Melphalan and Prednisone in Newly Diagnosed Transplant-Ineligible Multiple Myeloma (IFM 2012-03): A Phase I Trial by Leleu, Xavier, Fouquet, Guillemette, Richez, Valentine, Guidez, Stéphanie, Duhamel, Alain, Machuron, François, Karlin, Lionel, Kolb, Brigitte, Tiab, Mourad, Araujo, Carla, Meuleman, Nathalie, Malfuson, Jean-Valère, Bourquard, Pascal, Lenain, Pascal, Roussel, Murielle, Jaccard, Arnaud, Pétillon, Marie-Odile, Belhadj-Merzoug, Karim, Lepeu, Gérard, Chrétien, Marie-Lorraine, Fontan, Jean, Rodon, Philippe, Schmitt, Anna, Offner, Fritz, Voillat, Laurent, Cereja, Sophie, Kuhnowski, Frédérique, Rigaudeau, Sophie, Decaux, Olivier, Humbrecht-Kraut, Catherine, Frayfer, Jamile, Fitoussi, Olivier, Roos-Weil, Damien, Eisenmann, Jean-Claude, Dorvaux, Véronique, Voog, Eric G, Attal, Michel, Moreau, Philippe, Avet-Loiseau, Hervé, Hulin, Cyrille, Facon, Thierry

“…Carfilzomib is a novel generation proteasome inhibitor. The Carmysap trial demonstrated that twice-weekly KMP (carfilzomib, melphalan, prednisone) might…”
Get full text

Evaluation of the (R)VAD+C regimen for the treatment of newly diagnosed mantle cell lymphoma. Combined results of two prospective phase II trials from the French GOELAMS group by Gressin, Rémy, Caulet-Maugendre, Sylvie, Deconinck, Eric, Tournilhac, Olivier, Gyan, Emmanuel, Moles, Marie Pierre, El Yamani, Abderrazak, Cornillon, Jerome, Rossi, Jean François, Le Gouill, Steven, Lepeu, Gérard, Damaj, Ghandi, Celigny, Philippe Solal, Maisonneuve, Hervé, Corront, Bernadette, Vilque, Jean Pierre, Casassus, Philippe, Lamy, Thierry, Colonna, Marc, Colombat, Philippe

“…Background There is currently no international consensus for first-line treatment (prior to autologous stem cell transplantation) in mantle cell lymphoma…”
Get full text

Chlorambucil in Indolent Chronic Lymphocytic Leukemia by Dighiero, Guillaume, Maloum, Karim, Desablens, Bernard, Cazin, Bruno, Navarro, Maurice, Leblay, Robert, Leporrier, Michel, Jaubert, Jérome, Lepeu, Gérard, Dreyfus, Brigitte, Binet, Jacques-Louis, Travade, Philippe, Turpin, François-Louis, Tertian, Gérard, Bichoffe, Agnès

“…Many patients with chronic lymphocytic leukemia (CLL) have long lives and die of causes unrelated to the disease. 1 , 2 Rai's classification 3 – 5 and Binet's…”
Get full text

Deletion of the 1p32 region is a major independent prognostic factor in young patients with myeloma: the IFM experience on 1195 patients by Hebraud, B, Leleu, X, Lauwers-Cances, V, Roussel, M, Caillot, D, Marit, G, Karlin, L, Hulin, C, Gentil, C, Guilhot, F, Garderet, L, Lamy, T, Brechignac, S, Pegourie, B, Jaubert, J, Dib, M, Stoppa, A-M, Sebban, C, Fohrer, C, Fontan, J, Fruchart, C, Macro, M, Orsini-Piocelle, F, Lepeu, G, Sohn, C, Corre, J, Facon, T, Moreau, P, Attal, M, Avet-Loiseau, H

“…Deletions of the 1p region appear as a pejorative prognostic factor in multiple myeloma patients (especially 1p22 and 1p32 deletions) but there is a lack of…”
Get full text

Carfilzomib weekly plus melphalan and prednisone in newly diagnosed transplant-ineligible multiple myeloma (ifm 2012-03) by Leleu, Xavier, Fouquet, Guillemette, Richez, Valentine, Guidez, Stephanie, Duhamel, Alain, Machuron, François, Karlin, Lionel, Kolb, Brigitte, Tiab, Mourad, Araujo, Carla, Meuleman, Nathalie, Malfuson, Jean-Valere, Bourquard, Pascal, Lenain, Pascal, Roussel, Murielle, Jaccard, Arnaud, Petillon, Marie-Odile, Belhadj, Karim, Lepeu, Gerard, Chretien, Marie-Lorraine, Fontan, Jean, Rodon, Philippe, Schmitt, Anna, Offner, Fritz, Voillat, Laurent, Cereja, Sophie, Kuhnowski, Frederique, Rigaudeau, Sophie, Decaux, Olivier, Humbrecht-Kraut, Catherine, Frayfer, Jamile, Fitoussi, Olivier, Roos-Weil, Damien, Eisenmann, Jean Claude, Dorvaux, Veronique, Voog, Eric G., Attal, Michel, Moreau, Philippe, Avet-Loiseau, Herve, Hulin, Cyrille, Facon, Thierry

“…OBJECTIVE: Carfilzomib is a novel generation proteasome inhibitor. The Carmysap trial demonstrated that twice-weekly KMP (carfilzomib, melphalan, prednisone)…”
Get full text

Treatment of Good Prognosis CD20+ Large-Cell Lymphomas in Patients Aged 65 to 80, with 3 Cycles of R-CHOP14 Followed by An Injection of 90Y Ibritumomab Tiuxetan by Frederic, Peyrade, Gérard, Lepeu, Provencio, Mariano, Lauris, Gastaud, Xavier, Fontana, Jean-Marc, Broglia, Patricia, Carrier, Emmanuel, Chamorey, Christophe, Hebert, Thyss, Antoine

“…Background: Treatment of newly diagnosed DLBCL in patients aged 65 to 80 is based on 6 to 8 cycles of R-CHOP at 14 to 21 day intervals. Recent data suggest…”
Get full text

IFM2012-03 by Leleu, Xavier, Fouquet, Guillemette, Karlin, Lionel, Kolb, Brigitte, Tiab, Mourad, Araujo, Carla, Meuleman, Nathalie, Malfuson, Jv, Bourquard, Pascal, Lenain, Pascal, Roussel, Murielle, Jaccard, Arnaud, Petillon, Marie-Odile, Belhadj-Merzoug, Karim, Lepeu, Gerard, Chretien, Marie-Lorraine, Fontan, Jean, Rodon, Philippe, Schmitt, Anna, Offner, Fritz, Voillat, Laurent, Cereja, Sophie, Kuhnowski, Frederique, Rigaudeau, Sophie, Decaux, Olivier, Humbrecht-Kraut, Catherine, Frayfer, Jamile, Fitoussi, Olivier, Roos Weil, Damien, Eisenmann, Jean Claude, Dorvaux, Veronique, Voog, Eric G., Hulin, Cyrille, Attal, Michel, Moreau, Philippe, Facon, Thierry

“…Background. Melphalan plus prednisone and bortezomib combination is the most frequent standard of care used upfront for newly diagnosed elderly myeloma…”
Get full text

Carfilzomib Weekly Plus Melphalan and Prednisone in Newly Diagnosed Elderly Multiple Myeloma (IFM 2012-03) by Leleu, Xavier, Karlin, Lionel, Kolb, Brigitte, Tiab, Mourad, Araujo, Carla, Meuleman, Nathalie, De Revel, Thierry, Bourquard, Pascal, Lenain, Pascal, Roussel, Murielle, Jaccard, Arnaud, Petillon, Marie-Odile, Belhadj-Merzoug, Karim, Lepeu, Gerard, Chretien, Marie-Lorraine, Fontan, Jean, Rodon, Philippe, Schmitt, Anna, Offner, Fritz, Voillat, Laurent, Cereja, Sophie, Kuhnowski, Frederique, Rigaudeau, Sophie, Decaux, Olivier, Humbrecht-Kraut, Catherine, Frayfer, Jamile, Fitoussi, Olivier, Roos Weil, Damien, Eisenmann, Jean Claude, Dorvaux, Veronique, Voog, Eric G., Hulin, Cyrille, Attal, Michel, Moreau, Philippe, Facon, Thierry

“…▪ Background. New standards with increasing efficacy that are also characterized with improving the quality of life are needed for elderly myeloma patients…”
Get full text

Carfilzomib Weekly Plus Melphalan and Prednisone in Newly Diagnosed Elderly Multiple Myeloma (IFM 2012-03) / 57th Annual Meeting of the American-Society-of-Hematology - Orlando, FL by Leleu, Xavier, Karlin, Lionel, Kolb, Brigitte, Tiab, Mourad, Araujo, Carla, Meuleman, Nathalie, de Revel, Thierry, Bourquard, Pascal, Lenain, Pascal, Roussel, Murielle, Jaccard, Arnaud, Petillon, Marie-Odile, Belhadj-Merzoug, Karim, Lepeu, Gerard, Chretien, Marie-Lorraine, Fontan, Jean, Rodon, Philippe, Schmitt, Anna, Offner, Fritz, Voillat, Laurent, Cereja, Sophie, Kuhnowski, Frederique, Rigaudeau, Sophie, Decaux, Olivier, Humbrecht-Kraut, Catherine, Frayfer, Jamile, Fitoussi, Olivier, Weil, Damien Roos, Eisenmann, Jean Claude, Dorvaux, Véronique, Voog, Eric G., Hulin, Cyrille, Attal, Michel, Moreau, Philippe, Facon, Thierry

“…Conference: 57th Annual Meeting of the American-Society-of-Hematology - Orlando, FL - DEC 05-08, 2015…”
Get full text

Phase II study of short CHOP-rituximab combination with early consolidation with ibritumomab-tiuxetan-Y 90 (IT-Y 90 ) in non-pretreated patients age 65 to 80 with CD20+ diffuse large B-cell lymphoma (DLBCL) by Peyrade, Frederic, Lepeu, Gerard, Gal, Jocelyn, Fruchart, Christophe, Coso, Diane, Bologna, Serge, Provencio, Mariano, Kaphan, Regis, Sohn, Claudine, Audhuy, Bruno, Codina, Gomez, Thyss, Antoine

“…Abstract only 6633 Background: IT-Y 90 was approved in follicular lymphoma, and some data indicates that it could be used in DLBCL. It has been reported that…”
Get full text

Final results of a randomized phase II GELA/LYSA study of rituximab plus ACVBP or CHOP, using a PET-driven consolidation strategy, in patients with high-risk diffuse large B-cell lymphoma (DLBCL) by Casasnovas, Rene-Olivier, Ysebaert, Loic, Thieblemont, Catherine, Coiffier, Bertrand, Bologna, Serge, Lepeu, Gerard, Delmer, Alain, Plantier, Isabelle, Gabarre, Jean, Andre, Marc, Senecal, Delphine, Fruchart, Christophe, Meignan, Michel, Berriolo-Riedinger, Alina, Bardet, Stephane, Molina, Thierry Jo, Jais, Jean-Philippe, Haioun, Corinne, Tilly, Herve, Morschhauser, Franck

“…Abstract only…”
Get full text

1p22 and 1p32 Deletions Are Independent Prognosis Factors in Young Patients with Myeloma: The IFM Experience On 1195 Patients by Hebraud, Benjamin, Leleu, Xavier, lauwers-Cances, Valerie, Roussel, Murielle, Marit, Gerald, Karlin, Lionel, Hulin, Cyrille, Gentil, Catherine, Guilhot, Francois, Garderet, Laurent, Lamy, Thierry, Brechignac, Sabine, Pegourie, Brigitte, Jaubert, Jerome, Dib, Mamoun, Stoppa, Anne-Marie, Sebban, Catherine, Fohrer, Cecile, Fontan, Jean, Fruchart, Christophe, Bouscary, Didier, Corront, Bernadette, Lepeu, Gerard, Corre, Jill, Facon, Thierry, Attal, Michel, Moreau, Philippe, avet-Loiseau, Herve

“…Abstract ▪933▪This icon denotes a clinically relevant abstract Cytogenetics findings are the most important pronostic factor in multiple myeloma (MM) with age…”
Get full text

Rituximab and Reduced Dose CHOP (R-mini-CHOP) for Patients Over 80 Years with Diffuse Large B-Cell Lymphoma (DLBCL) – Groupe d'Etude Des Lymphomes De l'Adulte (GELA) Study LNH03-7B by Peyrade, Frederic, Jardin, Fabrice, Gisselbrecht, Christian, Thyss, Antoine, Emile, Jean François, Castaigne, Sylvie, Coiffier, Bertrand, Haioun, Corinne, Bologna, Serge, Fitoussi, Olivier, Lepeu, Gerard, Fruchart, Christophe, Bordessoule, Dominique, Blanc, Michel, Delarue, Richard, Janvier, Maud, Salles, Bruno, Bosly, Andre, Tilly, Herve

“…Abstract 853 Half of the cases of DLBCL occurs in patients over 65 years but very few data are available for patients over 80 years. These older patients…”
Get full text

Bortezomib Plus Dexamethasone (VD)Versus Reduced-dose bortezomib Plus Thalidomide Plus Dexametasone (vTD) as Induction Treatment Prior to Autologous Stem-Cell Transplantation (ASCT) in Newly Diagnosed Multiple Myeloma (MM) by Harousseau, Jean-Luc, Avet-Loiseau, Hervé, Facon, Thierry, Attal, Michel, Doyen, Chantal, Hulin, Cyrille, Garderet, Laurent, Tiab, Mourad, Lepeu, Gerard, Aranjo, Christine, Cailliot, Denis, Petillon, marie-Odile, Mathiot, Claire, Mary, Jean Yves, Moreau, Philippe

“…Abstract 354▪▪This icon denotes an abstract that is clinically relevant. The Intergroupe Francophone du Myelome (IFM) has shown that induction tteatment prior…”
Get full text

Multiple Myeloma Treatment in Real-world Clinical Practice: Results of a Prospective, Multinational, Noninterventional Study by Mohty, Mohamad, Lejniece, Sandra, Beksac, Meral, Bekadja, Mohamed Amine, Stankovic, Svetlana, De Stefano, Valerio, Kochkareva, Yulia, Laane, Edward, Salwender, Hans, Masliak, Zvenyslava, Silva, João, Louw, Vernon, Abadi, Uri, Couturier, Catherine, Feys, Caroline, Thoret-Bauchet, Florence, Bekadja, Mohamed, Ali, Hocine Ait, Hamdi, Selma, Touhami, Hadj, Pedersen, Robert Shou, Laane, Edward, Hein, Marju, Moreau, Philippe, Cartron, Guillaume, Dine, Gérard, Harich, Hanns-Detlev, Illmer, Thomas, Dörfel, Steffen, Koenigsmann, Michael, Schlag, Rudolf, Uhlig, Jens, Schütz, Stefan, Tessen, Hans-Werner, Mohr, Benno, Heinrich, Bernhard, Von Weikersthal, Ludwig Fischer, Heßling, Jörg, Schauer, Michael, Dürk, Heinz, Hess, Georg, Matsouka, Panagiota, Ivanyi, Janos, Abadi, Uri, Avivi, Irit, Foa, Roberto, Corso, Alessandro, Ferrara, Felicetto, Cantonetti, Maria, Di Raimondo, Francesco, Pizzuti, Michele, Farina, Gabriella, La Nasa, Giorgio, Cangialosi, Clotilde, Federici, Augusto, Romano, Atelda, Specchia, Giorgina, Latte, Giancarlo, Mannina, Donato, Pečeliūnas, Valdas, Jurgutis, Mindaugas, Stankovic, Svetlana, Homenda, Wojciech, Starzak-Gwozdz, Jolanta, Komarnicki, Mieczyslaw, Gonçalves, Cristina, Esefyeva, Natalia, Kochkareva, Julia, Kaplanov, Kamil, Laricheva, Elena, Dergacheva, Valentina, Nazarova, Irina, Anchukova, Ludmila, Ovanesova, Elena, Gritsenko, Taras, Kuznetsova, Irina, Osyunikhina, Svetlana, Serdyuk, Olga, Karyagina, Elena, Ivanova, Valentina, Gutiérrez, Asunción Echeveste, Capote, Francisco Javier, Sanchez, Jesus Martin, Ibañez-Garcia, Jeronima, Herranz, Maria Jose, Sanchez, Sara Sanchez, Lleonart, Joan Bargay, Martínez, Rafael, De La Serna, Javier, Mateos, Maria-Victoria, Beksac, Turkey – Meral, Aydin, Yildiz, Bilgir, Oktay, Ali, Ridvan, Kyselyova, Maryna, Dyagil, Iryna, Yushchenko, Natalia, Kozlov, Viktor, Harousseau, Jean-Luc, De la Rubia, Javier

“…Multiple myeloma (MM) remains an incurable disease, with little information available on its management in real-world clinical practice. The results of the…”
Get full text