Search Results - "Lepers, JP"

Plasmodium falciparum liver stage antigen-1 is well conserved and contains potent B and T cell determinants [published erratum appears in J Immunol 1994 Dec 1;153(11):5347] by Fidock, DA, Gras-Masse, H, Lepers, JP, Brahimi, K, Benmohamed, L, Mellouk, S, Guerin-Marchand, C, Londono, A, Raharimalala, L, Meis, JF

“…We have previously identified a Plasmodium falciparum liver stage-specific Ag (LSA-1) found to encode tandem 17 amino acid repeats harboring B cell…”
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A novel Plasmodium falciparum sporozoite and liver stage antigen (SALSA) defines major B, T helper, and CTL epitopes by Bottius, E, BenMohamed, L, Brahimi, K, Gras, H, Lepers, JP, Raharimalala, L, Aikawa, M, Meis, J, Slierendregt, B, Tartar, A, Thomas, A, Druilhe, P

“…In the search for subunit vaccines that are able to induce the type of sterile, protective immunity achieved by irradiated sporozoites, there is increasing…”
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Parasite virulence factors during falciparum malaria: rosetting, cytoadherence, and modulation of cytoadherence by cytokines by RINGWALD, P, PEYRON, F, LEPERS, J. P, RABARISON, P, RAKOTOMALALA, C, RAZANAMPARANY, M, MEJA RABODONIRINA, ROUX, J, LE BRAS, J

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Chromomycosis caused by Exophilia spinifera in Sahelian Africa by Develoux, M, Dieng, M-T, Ndiaye, B, Raphenon, G, Lepers, J-P

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Reappearance of falciparum malaria in central highland plateaux of Madagascar by Lepers, J P, Deloron, P, Fontenille, D, Coulanges, P

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A novel merozoite surface antigen of Plasmodium falciparum (MSP-3) identified by cellular-antibody cooperative mechanism antigenicity and biological activity of antibodies by Oeuvray, C, Bouharoun-Tayoun, H, Grass-Masse, H, Lepers, J P, Ralamboranto, L, Tartar, A, Druilhe, P

“…We report the identification of a 48kDa antigen targeted by antibodies which inhibit Plasmodium falciparum in vitro growth by cooperation with blood monocytes…”
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Protective value of elevated levels of gamma interferon in serum against exoerythrocytic stages of Plasmodium falciparum by DELORON, P, CHOUGNET, C, LEPERS, J. P, TALLET, S, COULANGES, P

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Isotypic analysis of Plasmodium falciparum-specific antibodies and their relation to protection in Madagascar by DUBOIS, B, DELORON, P, ASTAGNEAU, P, CHOUGNET, C, LEPERS, J. P

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Human immune responses to the Plasmodium falciparum ring-infected erythrocyte surface antigen (Pf155/RESA) after a decrease in malaria transmission in Madagascar by Migot, F, Chougnet, C, Raharimalala, L, Astagneau, P, Lepers, J P, Deloron, P

“…A resurgence of falciparum malaria occurred in the central highlands of Madagascar in the 1980s and was responsible for an outbreak in 1986-1987. Since 1989,…”
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Failure to detect MHC class II associations of the human immune response induced by repeated malaria infections to the Plasmodium falciparum antigen Pf155/RESA by Troye-Blomberg, M, Olerup, O, Larsson, A, Sjöberg, K, Perlmann, H, Riley, E, Lepers, J P, Perlmann, P

“…Available evidence suggests that human T and B cell responses to a major Plasmodium falciparum malaria antigen (Pf155/RESA) in individuals primed by repeated…”
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Human immune response in Plasmodium falciparum malaria. Synthetic peptides corresponding to known epitopes of the Pf155/RESA antigen induce production of parasite-specific antibodies in vitro by Chougnet, C, Troye-Blomberg, M, Deloron, P, Kabilan, L, Lepers, JP, Savel, J, Perlmann, P

“…Autologous cell mixtures containing T cells, B cells, and adherent accessory cells from individuals primed to the malaria parasite Plasmodium falciparum by…”
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Antibodies to the 4-mer repeat of the ring-infected erythrocyte surface antigen (Pf155/RESA) protect against Plasmodium falciparum malaria by Astagneau, P, Chougnet, C, Lepers, J P, Danielle, M, Andriamangatiana-Rason, M D, Deloron, P

“…To investigate the protective role of antibodies to the ring-infected erythrocyte surface antigen (Pf155/RESA) epitopes against Plasmodium falciparum clinical…”
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Humoral and cell-mediated immune responses to the Plasmodium falciparum antigens PF155/RESA and CS protein: seasonal variations in a population recently reexposed to endemic malaria by Chougnet, C, Deloron, P, Lepers, J P, Tallet, S, Rason, M D, Astagneau, P, Savel, J, Coulanges, P

“…Resurgence of falciparum malaria occurred in the Central Highlands of Madagascar in the 1980s and the disease is currently hyperendemic. We determined the…”
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Lack of correlation between HLA class II alleles and immune responses to Pf155/ring-infected erythrocyte surface antigen (RESA) from Plasmodium falciparum in Madagascar by Migot, F, Chougnet, C, Perichon, B, Danze, P M, Lepers, J P, Krishnamoorthy, R, Deloron, P

“…To investigate the relationships between predominant HLA class II alleles and immune responses to the Plasmodium falciparum ring-infected erythrocyte surface…”
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Plasmodium falciparum liver stage antigen-1 is well conserved and contains potent B and T cell determinants by Fidock, DA, Gras-Masses, H, Lepers, JP, Brahimi, K, Benmohamed, L, Mellouk, S, Guerin-Marchand, C, Londono, A, Raharimalala, L, Meis, JF, Langsley, Roussilhon, Tartar, Druilhe

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Evaluation of a nonisotopic DNA assay kit for diagnosing Plasmodium falciparum malaria in Madagascar by McLaughlin, G L, Subramanian, S, Lepers, J P, Raharimalala, L, Deloron, P

“…This study evaluated a nonisotopic DNA assay kit for diagnosing Plasmodium falciparum malaria in an area of Madagascar where all Plasmodium species of human…”
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Chronotherapy of malaria: improved efficacy of timed chloroquine treatment of patients with Plasmodium falciparum infections by Landau, I, Lepers, J P, Ringwald, P, Rabarison, P, Ginsburg, H, Chabaud, A

“…The effect of routine treatment with chloroquine (10 mg/kg on days 1 and 2 and 5 mg/kg on day 3) on parasitaemia and parasitaemic profile of patients infected…”
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Chloroquine for treatment of falciparum malaria in Madagascar by Lepers, J P, Deloron, P, Lepers-Ranson, M D, Raharimalala, L, Roux, J

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IgG1 and IgG2 antibody responses to Plasmodium falciparum exoantigens correlate inversely and positively, respectively, to the number of malaria attacks by Chumpitazi, B.F.F., Lepers, J.-P., Simon, J., Deloron, P.

“…In Manarintsoa, near Antananarivo, Madagascar, two groups of patients were defined in terms of malaria clinical immune status: Group MA + consisted of 36…”
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Presentation of the Plasmodium falciparum antigen Pf155/RESA to human T cells. Variations in responsiveness induced by antigen presenting cells from different but MHC class II identical donors by Troye-Blomberg, M, Lepers, J P, Sjöberg, K, Rahalimalala, L, Larsson, A, Olerup, O, Perlmann, P

“…The antibody response in humans naturally primed to a malaria vaccine candidate antigen (Pf155/RESA) is genetically regulated. Here, the impact of antigen…”
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