Search Results - "Leonor, M"

Bifidobacterium pseudocatenulatum CECT 7765 reverses the adverse effects of diet-induced obesity through the gut-bone axis by Fernández-Murga, M. Leonor, Olivares, Marta, Sanz, Yolanda

“…Obesity and the associated chronic metabolic diseases (e.g., type-2 diabetes) adversely affect bone metabolism and health. Gut microbiota is considered to be…”
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Musculoskeletal complications associated with pathological iron toxicity and its molecular mechanisms by Simão, Márcio, Cancela, M Leonor

“…Iron is fundamental for several biological functions, but when in excess can lead to the development of toxic events. Some tissues and cells are more…”
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The Anti-Neuroinflammatory Role of Anthocyanins and Their Metabolites for the Prevention and Treatment of Brain Disorders by Henriques, Joana F, Serra, Diana, Dinis, Teresa C P, Almeida, Leonor M

“…Anthocyanins are naturally occurring polyphenols commonly found in fruits and vegetables. Numerous studies have described that anthocyanin-rich foods may play…”
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Motivations and Constraints for the Ghost Tourism: A Case Study in Spain by Dancausa, Genoveva, Hernández, Ricardo D., Pérez, Leonor M.

“…Ghost tourism is emerging in numerous destinations all around world. This paper examines the motivations for participating in ghost tourism using the push-pull…”
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Host-Microbe Co-metabolism Dictates Cancer Drug Efficacy in C. elegans by Scott, Timothy A., Quintaneiro, Leonor M., Norvaisas, Povilas, Lui, Prudence P., Wilson, Matthew P., Leung, Kit-Yi, Herrera-Dominguez, Lucia, Sudiwala, Sonia, Pessia, Alberto, Clayton, Peter T., Bryson, Kevin, Velagapudi, Vidya, Mills, Philippa B., Typas, Athanasios, Greene, Nicholas D.E., Cabreiro, Filipe

“…Fluoropyrimidines are the first-line treatment for colorectal cancer, but their efficacy is highly variable between patients. We queried whether gut…”
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Coordinated Acetylcholine Release in Prefrontal Cortex and Hippocampus Is Associated with Arousal and Reward on Distinct Timescales by Teles-Grilo Ruivo, Leonor M., Baker, Keeley L., Conway, Michael W., Kinsley, Peter J., Gilmour, Gary, Phillips, Keith G., Isaac, John T.R., Lowry, John P., Mellor, Jack R.

“…Cholinergic neurotransmission throughout the neocortex and hippocampus regulates arousal, learning, and attention. However, owing to the poorly characterized…”
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Consuming safe hotels during the COVID-19 pandemic: the case of Spain by Pérez, Leonor M., Alonso, Mercedes, Rodríguez, Maribel

“…Since the beginning of the COVID-19 pandemic, many hotels have become safe hotels. Nevertheless, the understanding of the consumption of safe hotels is very…”
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The impact of egoistic and social-altruistic values on consumers' intention to stay at safe hotels in the COVID-19 era: a study in Spain by Rodríguez, Maribel, Pérez, Leonor M., Alonso, Mercedes

“…Currently, many individuals are willing to travel depending on the safety and hygiene measures against COVID-19 that exist throughout the trip, including the…”
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Safety Assessment of Bacteroides uniformis CECT 7771 Isolated from Stools of Healthy Breast-Fed Infants by Fernández-Murga, M Leonor, Sanz, Yolanda

“…Bacteroides uniformis CECT 7771 is a potential probiotic strain, originally isolated from the stools of healthy breast-feed infants. The strain showed…”
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Environmental impact of pharmaceuticals from Portuguese wastewaters: geographical and seasonal occurrence, removal and risk assessment by Pereira, André M.P.T., Silva, Liliana J.G., Meisel, Leonor M., Lino, Celeste M., Pena, Angelina

“…The occurrence, fate, geographical and seasonal influence and environmental risk assessment of eleven of the most consumed pharmaceuticals in Portugal were…”
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Increased axonal bouton dynamics in the aging mouse cortex by Grillo, Federico W, Song, Sen, Teles-Grilo Ruivo, Leonor M, Huang, Lieven, Gao, Ge, Knott, Graham W, Maco, Bohumil, Ferretti, Valentina, Thompson, Dawn, Little, Graham E, De Paola, Vincenzo

“…Aging is a major risk factor for many neurological diseases and is associated with mild cognitive decline. Previous studies suggest that aging is accompanied…”
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Host-Microbe-Drug-Nutrient Screen Identifies Bacterial Effectors of Metformin Therapy by Pryor, Rosina, Norvaisas, Povilas, Marinos, Georgios, Best, Lena, Thingholm, Louise B., Quintaneiro, Leonor M., De Haes, Wouter, Esser, Daniela, Waschina, Silvio, Lujan, Celia, Smith, Reuben L., Scott, Timothy A., Martinez-Martinez, Daniel, Woodward, Orla, Bryson, Kevin, Laudes, Matthias, Lieb, Wolfgang, Houtkooper, Riekelt H., Franke, Andre, Temmerman, Liesbet, Bjedov, Ivana, Cochemé, Helena M., Kaleta, Christoph, Cabreiro, Filipe

“…Metformin is the first-line therapy for treating type 2 diabetes and a promising anti-aging drug. We set out to address the fundamental question of how gut…”
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Assessment of MGP gene expression in cancer and contribution to prognosis by Caiado, Helena, Cancela, M. Leonor, Conceição, Natércia

“…Matrix Gla protein (MGP) was first identified as a calcification physiological inhibitor and the causal agent of the Keutel syndrome. MGP has been suggested to…”
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Resveratrol-Mediated Reversal of Doxorubicin-Induced Osteoclast Differentiation by Poudel, Sunil, Martins, Gil, Cancela, M Leonor, Gavaia, Paulo J

“…Secondary osteoporosis has been associated with cancer patients undertaking Doxorubicin (DOX) chemotherapy. However, the molecular mechanisms behind…”
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Use of pure recombinant human enzymes to assess the disease-causing potential of missense mutations in urea cycle disorders, applied to N-acetylglutamate synthase deficiency by Gougeard, Nadine, Sancho-Vaello, Enea, Fernández-Murga, M Leonor, Martínez-Sinisterra, Borja, Loukili-Hassani, Badr, Häberle, Johannes, Marco-Marín, Clara, Rubio, Vicente

“…N-acetylglutamate synthase (NAGS) makes acetylglutamate, the essential activator of the first, regulatory enzyme of the urea cycle, carbamoyl phosphate…”
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The Impact of Chronic Intestinal Inflammation on Brain Disorders: the Microbiota-Gut-Brain Axis by Serra, Diana, Almeida, Leonor M., Dinis, Teresa C. P.

“…It has been shown that the gut microbiota plays a crucial role in the maintenance of intestinal homeostasis. Additionally, it has been demonstrated that…”
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Incentives and constraints for archeological tourism: a case study in Spain by Rodríguez, Maribel, Pérez, Leonor M.

“…Archeological tourism has great potential for development in numerous destinations. However, literature on archeotourism is scarce and empirical data are very…”
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Multiobjective evolutionary algorithms to identify highly autocorrelated areas: the case of spatial distribution in financially compromised farms by García-Alonso, Carlos R., Pérez-Naranjo, Leonor M., Fernández-Caballero, Juan C.

“…Local Indicators of Spatial Aggregation (LISA) can be used as objectives in a multicriteria framework when highly autocorrelated areas (hot-spots) must be…”
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FBP17 and CIP4 recruit SHIP2 and lamellipodin to prime the plasma membrane for fast endophilin-mediated endocytosis by Chan Wah Hak, Laura, Khan, Shaheen, Di Meglio, Ilaria, Law, Ah-Lai, Lucken-Ardjomande Häsler, Safa, Quintaneiro, Leonor M., Ferreira, Antonio P. A., Krause, Matthias, McMahon, Harvey T., Boucrot, Emmanuel

“…Endocytosis mediates the cellular uptake of micronutrients and the turnover of plasma membrane proteins. Clathrin-mediated endocytosis is the major uptake…”
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Comparison of anti-inflammatory activities of an anthocyanin-rich fraction from Portuguese blueberries (Vaccinium corymbosum L.) and 5-aminosalicylic acid in a TNBS-induced colitis rat model by Pereira, Sónia R, Pereira, Rita, Figueiredo, Isabel, Freitas, Victor, Dinis, Teresa C P, Almeida, Leonor M

“…Despite the actual therapeutic approaches for inflammatory bowel disease (IBD), efficient and secure alternative options remain a research focus. In this…”
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