Search Results - "Leong, Rupert W."

Impaired Intestinal Permeability Contributes to Ongoing Bowel Symptoms in Patients With Inflammatory Bowel Disease and Mucosal Healing by Chang, Jeff, Dr, Leong, Rupert W., Professor, Wasinger, Valerie, Dr, Ip, Matthew, Dr, Yang, Michael, Dr, Giang Phan, Tri, Dr

“…Abstract Background & Aims Many patients with inflammatory bowel diseases (IBD) have ongoing bowel symptoms of diarrhea or abdominal pain despite mucosal…”
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Multidonor intensive faecal microbiota transplantation for active ulcerative colitis: a randomised placebo-controlled trial by Paramsothy, Sudarshan, MD, Kamm, Michael A, Prof, Kaakoush, Nadeem O, PhD, Walsh, Alissa J, MD, van den Bogaerde, Johan, PhD, Samuel, Douglas, MMed, Leong, Rupert W L, Prof, Connor, Susan, PhD, Ng, Watson, PhD, Paramsothy, Ramesh, MD, Xuan, Wei, PhD, Lin, Enmoore, PhD, Mitchell, Hazel M, Prof, Borody, Thomas J, Prof

“…Summary Background The intestinal microbiota is implicated in the pathogenesis of ulcerative colitis. Faecal microbiota transplantation is a novel form of…”
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Crohn's disease associated strictures by Chan, Webber Pak Wo, Mourad, Fadi, Leong, Rupert WL

“…Crohn's disease (CD) is a chronic relapsing and remitting disease that can affect any segments of the gastrointestinal tract. More than 50% of patients with CD…”
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A Phase 2 Study of Allogeneic Mesenchymal Stromal Cells for Luminal Crohn's Disease Refractory to Biologic Therapy by Forbes, Geoffrey M, Sturm, Marian J, Leong, Rupert W, Sparrow, Miles P, Segarajasingam, Dev, Cummins, Adrian G, Phillips, Michael, Herrmann, Richard P

“…Background & Aims Transplantation of peripheral blood stem cells has been successful therapy for small numbers of patients with Crohn's disease (CD), but…”
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Crohn's disease management after intestinal resection: a randomised trial by De Cruz, Peter, PhD, Kamm, Michael A, Prof, Hamilton, Amy L, BSc, Ritchie, Kathryn J, RN, Krejany, Efrosinia O, MSc, Gorelik, Alexandra, MSc, Liew, Danny, Prof, Prideaux, Lani, PhD, Lawrance, Ian C, Prof, Andrews, Jane M, Prof, Bampton, Peter A, MD, Gibson, Peter R, Prof, Sparrow, Miles, MBBS, Leong, Rupert W, Prof, Florin, Timothy H, Prof, Gearry, Richard B, PhD, Radford-Smith, Graham, PhD, Macrae, Finlay A, Prof, Debinski, Henry, MD, Selby, Warwick, MD, Kronborg, Ian, MBBS, Johnston, Michael J, MBBS, Woods, Rodney, MBBS, Elliott, P Ross, MD, Bell, Sally J, MD, Brown, Steven J, PhD, Connell, William R, MD, Desmond, Paul V, MBBS

“…Summary Background Most patients with Crohn's disease need an intestinal resection, but a majority will subsequently experience disease recurrence and require…”
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Ulcerative Colitis and Cytomegalovirus Infection: From A to Z by Mourad, Fadi H, Hashash, Jana G, Kariyawasam, Viraj C, Leong, Rupert W

“…Abstract Despite multiple studies, the role of cytomegalovirus [CMV] infection in exacerbating the severity of inflammation in ulcerative colitis [UC], and its…”
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Consensus Statements on Assessments and Vaccinations Prior to Commencement of Advanced Therapies for the Treatment of Inflammatory Bowel Diseases by Leong, Rupert W, Sakiris, Anthony, Arzivian, Arteen, Chetwood, John David, Chaemsupaphan, Thanaboon, Sparrow, Miles P, Kamm, Michael A, Kariayawasam, Viraj

“…Given the introduction of new advanced therapies for inflammatory bowel diseases (IBDs), expanded risk mitigation strategies are essential. To create a…”
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Environmental risk factors in inflammatory bowel disease: a population-based case-control study in Asia-Pacific by Ng, Siew C, Tang, Whitney, Leong, Rupert W, Chen, Minhu, Ko, Yanna, Studd, Corrie, Niewiadomski, Ola, Bell, Sally, Kamm, Michael A, de Silva, H J, Kasturiratne, Anuradhani, Senanayake, Yasith Udara, Ooi, Choon Jin, Ling, Khoon-Lin, Ong, David, Goh, Khean Lee, Hilmi, Ida, Ouyang, Qin, Wang, Yu-Fang, Hu, PinJin, Zhu, Zhenhua, Zeng, Zhirong, Wu, Kaichun, Wang, Xin, Xia, Bing, Li, Jin, Pisespongsa, Pises, Manatsathit, Sathaporn, Aniwan, Satimai, Simadibrata, Marcellus, Abdullah, Murdani, Tsang, Steve W C, Wong, Tai Chiu, Hui, Aric J, Chow, Chung Mo, Yu, Hon Ho, Li, Mo Fong, Ng, Ka Kei, Ching, Jessica, Wu, Justin C Y, Chan, Francis K L, Sung, Joseph J Y

“…The rising incidence of inflammatory bowel disease in Asia supports the importance of environmental risk factors in disease aetiology. This prospective…”
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Ustekinumab is effective and safe for ulcerative colitis through 2 years of maintenance therapy by Panaccione, Remo, Danese, Silvio, Sandborn, William J., O'Brien, Christopher D., Zhou, Yiying, Zhang, Hongyan, Adedokun, Omoniyi J., Tikhonov, Ilia, Targan, Stephan, Abreu, Maria T., Hisamatsu, Tadakazu, Scherl, Ellen J., Leong, Rupert W., Rowbotham, David S., Arasaradnam, Ramesh P., Sands, Bruce E., Marano, Colleen

“…Summary Background The ongoing UNIFI long‐term extension evaluates subcutaneous ustekinumab for moderate‐to‐severe ulcerative colitis (UC) from weeks 44…”
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Efficacy and Safety of Maintenance Ustekinumab for Ulcerative Colitis Through 3 Years: UNIFI Long-term Extension by Abreu, Maria T, Rowbotham, David S, Danese, Silvio, Sandborn, William J, Miao, Ye, Zhang, Hongyan, Tikhonov, Ilia, Panaccione, Remo, Hisamatsu, Tadakazu, Scherl, Ellen J, Leong, Rupert W, Arasaradnam, Ramesh P, Afif, Waqqas, Peyrin-Biroulet, Laurent, Sands, Bruce E, Marano, Colleen

“…Abstract Background and Aims The UNIFI long-term extension [LTE] study reports the efficacy and safety of subcutaneous 90 mg ustekinumab through 3 years of…”
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Review of pregnancy in Crohn’s disease and ulcerative colitis by Laube, Robyn, Paramsothy, Sudarshan, Leong, Rupert W.

“…Inflammatory bowel disease (IBD) frequently affects women of childbearing age and can have implications in pregnancy. Most women with IBD have comparable…”
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The phageome of patients with ulcerative colitis treated with donor fecal microbiota reveals markers associated with disease remission by Majzoub, Marwan E., Paramsothy, Sudarshan, Haifer, Craig, Parthasarathy, Rohit, Borody, Thomas J., Leong, Rupert W., Kamm, Michael A., Kaakoush, Nadeem O.

“…Bacteriophages are influential within the human gut microbiota, yet they remain understudied relative to bacteria. This is a limitation of studies on fecal…”
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Epidemiological studies of migration and environmental risk factors in the inflammatory bowel diseases by Ko, Yanna, Butcher, Rhys, Leong, Rupert W

“…Inflammatory bowel diseases(IBD)are idiopathic chronic diseases of the gastrointestinal tract well known to be associated with both genetic and environmental…”
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Comparing persistence of new biologics to conventional anti-TNF alphas in adult patients with inflammatory bowel disease: a systematic review and meta-analysis protocol by Yiu, Tsz Hong, Ko, Yanna, Pudipeddi, Aviv, Natale, Patrizia, Leong, Rupert W

“…BackgroundBiological therapy is a cornerstone of managing moderate-to-severe inflammatory bowel disease (IBD), ulcerative colitis (UC) and Crohn’s disease…”
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Sex differences in epidemiological, clinical and pathological characteristics of colorectal cancer by Koo, Jenn Hian, Leong, Rupert WL

“…Sex significantly influences the clinical and pathological characteristics of colorectal cancer (CRC). These include differences in incidence and mortality…”
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Vedolizumab has longer persistence than infliximab as a first-line biological agent but not as a second-line biological agent in moderate-to-severe ulcerative colitis: real-world registry data from the Persistence Australian National IBD Cohort (PANIC) study by Pudipeddi, Aviv, Ko, Yanna, Paramsothy, Sudarshan, Leong, Rupert W.

“…Background: The choice between infliximab (IFX) and vedolizumab (VED) as a first-line biological agent in moderate-to-severe ulcerative colitis (UC) can be…”
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Tryptophan Metabolism 'Hub' Gene Expression Associates with Increased Inflammation and Severe Disease Outcomes in COVID-19 Infection and Inflammatory Bowel Disease by Bustamante, Sonia, Yau, Yunki, Boys, Victoria, Chang, Jeff, Paramsothy, Sudarshan, Pudipeddi, Aviv, Leong, Rupert W, Wasinger, Valerie C

“…The epithelial barrier's primary role is to protect against entry of foreign and pathogenic elements. Both COVID-19 and Inflammatory Bowel Disease (IBD) show…”
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Serological Epithelial Component Proteins Identify Intestinal Complications in Crohn's Disease by Yau, Yunki Y., Leong, Rupert W.L., Pudipeddi, Aviv, Redmond, Diane, Wasinger, Valerie C.

“…Crohn's Disease (CD) is a relapsing inflammation of the gastrointestinal tract that affects a young working age population and is increasing in developing…”
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Medication adherence in women with IBD of childbearing age likely associated with disease knowledge by Laube, Robyn, Selinger, Christian, Leong, Rupert W.

“…Background: Medication adherence in inflammatory bowel disease (IBD) is crucial, particularly during pregnancy. Unplanned pregnancies are common; therefore,…”
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Misconceptions Drive COVID-19 Vaccine Hesistancy in Individuals with Inflammatory Bowel Disease by Zhang, Eva, Gupta, Arun, Al-Ani, Aysha, Macrae, Finlay A., Leong, Rupert W., Christensen, Britt

“…Background. Vaccination is an effective public health measure to combat the SARS-CoV-2 pandemic. However, vaccine “hesitancy” has limited uptake in some,…”
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