Search Results - "Leong, Lex E.X"

Whole-Genome Sequencing of SARS-CoV-2 from Quarantine Hotel Outbreak by Leong, Lex E.X, Soubrier, Julien, Turra, Mark, Denehy, Emma, Walters, Luke, Kassahn, Karin, Higgins, Geoff, Dodd, Tom, Hall, Robert, D'Onise, Katina, Spurrier, Nicola, Bastian, Ivan, Lim, Chuan K

“…Hotel quarantine for international travelers has been used to prevent coronavirus disease spread into Australia. A quarantine hotel–associated community…”
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Multistate Outbreak of Salmonella enterica Serovar Heidelberg with Unidentified Source, Australia, 2018-2019 by Kerr, Elenor J, Stafford, Russell, Rathnayake, Irani U, Graham, Rikki M A, Fearnley, Emily, Gregory, Joy, Glasgow, Keira, Wright, Rose, Sintchenko, Vitali, Wang, Qinning, Howard, Peter, Leong, Lex E X, Valcanis, Mary, Pitchers, William, Lambert, Stephen B, Jennison, Amy V

“…We report a multistate Salmonella enterica serovar Heidelberg outbreak in Australia during 2018-2019. Laboratory investigation of cases reported across 5…”
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Burkholderia lata Infections from Intrinsically Contaminated Chlorhexidine Mouthwash, Australia, 2016 by Leong, Lex E X, Lagana, Diana, Carter, Glen P, Wang, Qinning, Smith, Kija, Stinear, Tim P, Shaw, David, Sintchenko, Vitali, Wesselingh, Steven L, Bastian, Ivan, Rogers, Geraint B

“…Burkholderia lata was isolated from 8 intensive care patients at 2 tertiary hospitals in Australia. Whole-genome sequencing demonstrated that clinical and…”
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Vibrio parahaemolyticus Foodborne Illness Associated with Oysters, Australia, 2021-2022 by Fearnley, Emily, Leong, Lex E X, Centofanti, Alessia, Dowsett, Paul, Combs, Barry G, Draper, Anthony D K, Hocking, Helen, Howden, Ben, Horan, Kristy, Wilmot, Mathilda, Levy, Avram, Cooley, Louise A, Kennedy, Karina J, Wang, Qinning, Arnott, Alicia, Graham, Rikki M A, Sinchenko, Vitali, Jennison, Amy V, Kane, Stacey, Wright, Rose

“…The bacterium Vibrio parahaemolyticus is ubiquitous in tropical and temperate waters throughout the world and causes infections in humans resulting from water…”
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Clinical and symptom scores are significantly correlated with fecal microbiota features in patients with symptomatic uncomplicated diverticular disease: a pilot study by Kvasnovsky, Charlotte L, Leong, Lex E.X, Choo, Jocelyn M, Abell, Guy C.J, Papagrigoriadis, Savvas, Bruce, Kenneth D, Rogers, Geraint B

“…BACKGROUNDThere is growing consensus that symptomatic uncomplicated diverticular disease is a chronic inflammatory condition, and that alterations in the fecal…”
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Identification of the mechanism for dehalorespiration of monofluoroacetate in the phylum Synergistota by Leong, Lex E. X., Denman, Stuart E., Kang, Seungha, Mondot, Stanislas, Hugenholtz, Philip, McSweeney, Chris S.

“…Objective: Monofluoroacetate (MFA) is a potent toxin that blocks ATP production via the Krebs cycle and causes acute toxicity in ruminants consuming…”
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The microbiome of otitis media with effusion in Indigenous Australian children by Jervis-Bardy, Jake, Rogers, Geraint B, Morris, Peter S, Smith-Vaughan, Heidi C, Nosworthy, Elizabeth, Leong, Lex E.X, Smith, Renee J, Weyrich, Laura S, De Haan, Jacques, Carney, A. Simon, Leach, Amanda J, O’Leary, Stephen, Marsh, Robyn L

“…Abstract Introduction Indigenous Australian children have a high prevalence of otitis media with effusion (OME) and associated conductive hearing loss. Only…”
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Resistome Analysis of Klebsiella pneumoniae Complex from Residential Aged Care Facilities Demonstrates Intra-facility Clonal Spread of Multidrug-Resistant Isolates by Blaikie, Jack M, Sapula, Sylvia A, Siderius, Naomi L, Hart, Bradley J, Amsalu, Anteneh, Leong, Lex E X, Warner, Morgyn S, Venter, Henrietta

“…Antimicrobial-resistant is one of the predominant pathogens in healthcare settings. However, the prevalence and resistome of this organism within residential…”
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Sample storage conditions significantly influence faecal microbiome profiles by Choo, Jocelyn M, Leong, Lex EX, Rogers, Geraint B

“…Sequencing-based studies of the human faecal microbiota are increasingly common. Appropriate storage of sample material is essential to avoid the introduction…”
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Effect of azithromycin on asthma exacerbations and quality of life in adults with persistent uncontrolled asthma (AMAZES): a randomised, double-blind, placebo-controlled trial by Gibson, Peter G, Yang, Ian A, Upham, John W, Reynolds, Paul N, Hodge, Sandra, James, Alan L, Jenkins, Christine, Peters, Matthew J, Marks, Guy B, Baraket, Melissa, Powell, Heather, Taylor, Steven L, Leong, Lex E X, Rogers, Geraint B, Simpson, Jodie L

“…Exacerbations of asthma cause a substantial global illness burden. Adults with uncontrolled persistent asthma despite maintenance treatment require additional…”
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Inflammatory phenotypes in patients with severe asthma are associated with distinct airway microbiology by Taylor, Steven L., Leong, Lex E.X., Choo, Jocelyn M., Wesselingh, Steve, Yang, Ian A., Upham, John W., Reynolds, Paul N., Hodge, Sandra, James, Alan L., Jenkins, Christine, Peters, Matthew J., Baraket, Melissa, Marks, Guy B., Gibson, Peter G., Simpson, Jodie L., Rogers, Geraint B.

“…Asthma pathophysiology and treatment responsiveness are predicted by inflammatory phenotype. However, the relationship between airway microbiology and asthma…”
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Impact of COVID-19 Containment Strategies and Meningococcal Conjugate ACWY Vaccination on Meningococcal Carriage in Adolescents by McMillan, Mark, Bednarz, Jana, Leong, Lex E.X., Lawrence, Andrew, Marshall, Helen S.

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Long-Term Azithromycin Reduces Haemophilus influenzae and Increases Antibiotic Resistance in Severe Asthma by Taylor, Steven L, Leong, Lex E X, Mobegi, Fredrick M, Choo, Jocelyn M, Wesselingh, Steve, Yang, Ian A, Upham, John W, Reynolds, Paul N, Hodge, Sandra, James, Alan L, Jenkins, Christine, Peters, Matthew J, Baraket, Melissa, Marks, Guy B, Gibson, Peter G, Rogers, Geraint B, Simpson, Jodie L

“…The macrolide antibiotic azithromycin reduces exacerbations in adults with persistent symptomatic asthma. However, owing to the pleotropic properties of…”
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Impact of COVID-19 Containment Strategies and Meningococcal Conjugate ACWY Vaccination on Meningococcal Carriage in Adolescents by McMillan, Mark, Bednarz, Jana, Leong, Lex E.X., Lawrence, Andrew, Marshall, Helen S.

“…OBJECTIVESTo examine if COVID-19 containment strategies were associated with reduced pharyngeal carriage of meningococci in adolescents. Also, to observe if…”
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Impact of meningococcal B (4CMenB) vaccine on pharyngeal Neisseria meningitidis carriage density and persistence in adolescents by McMillan, Mark, Walters, Luke, Sullivan, Thomas, Leong, Lex E X, Turra, Mark, Lawrence, Andrew, Koehler, Ann P, Finn, Adam, Andrews, Ross M, Marshall, Helen S

“…Higher density of Neisseria meningitidis carriage may be associated with transmission of the meningococcus. Our aim was to establish the impact of 4CMenB…”
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Direct whole-genome sequencing of HIV-1 for clinical drug-resistance analysis and public health surveillance by Coldbeck-Shackley, Rosa C., Adamson, Penelope J., Whybrow, Daryn, Selway, Caitlin A., Papanicolas, Lito E., Turra, Mark, Leong, Lex E.X.

“…•Outlines a robust HIV-1 direct WGS method for clinical samples.•Optimised extraction and DNAse I treatment improves HIV-1 genome recovery.•High-quality…”
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Vibrio parahaemolyticus Food borne Illness Associated with Oysters, Australia, 2021-2022 by Fearnley, Emily, Leong, Lex E.X, Centofanti, Alessia, Dowsett, Paul, Combs, Barry G, Draper, Anthony D.K, Hocking, Helen, Howden, Ben, Horan, Kristy, Wilmot, Mathilda, Levy, Avram, Cooley, Louise A, Kennedy, Karina J, Wang, Qinning, Arnott, Alicia, Graham, Rikki M.A, Sinchenko, Vitali, Jennison, Amy V, Kane, Stacey, Wright, Rose

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Bacterial viability in faecal transplants: Which bacteria survive? by Papanicolas, Lito E., Choo, Jocelyn M., Wang, Yanan, Leong, Lex E.X., Costello, Samuel P., Gordon, David L., Wesselingh, Steve L., Rogers, Geraint B.

“…The therapeutic potential of faecal microbiota transplantation (FMT) is under investigation for a range of inflammatory conditions. While mechanisms of benefit…”
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Deriving accurate microbiota profiles from human samples with low bacterial content through post-sequencing processing of Illumina MiSeq data by Jervis-Bardy, Jake, Leong, Lex E X, Marri, Shashikanth, Smith, Renee J, Choo, Jocelyn M, Smith-Vaughan, Heidi C, Nosworthy, Elizabeth, Morris, Peter S, O'Leary, Stephen, Rogers, Geraint B, Marsh, Robyn L

“…The rapid expansion of 16S rRNA gene sequencing in challenging clinical contexts has resulted in a growing body of literature of variable quality. To a large…”
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Soluble fibre supplementation with and without a probiotic in adults with asthma: A 7-day randomised, double blind, three way cross-over trial by McLoughlin, Rebecca, Berthon, Bronwyn S., Rogers, Geraint B., Baines, Katherine J., Leong, Lex E.X., Gibson, Peter G., Williams, Evan J., Wood, Lisa G.

“…Soluble fibre modulates airway inflammation in animal models. The aim of this study was to investigate the effects of soluble fibre supplementation, with and…”
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