Search Results - "Leong, Keith Weng Kit"

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    Tyrosine Dephosphorylation of ASC Modulates the Activation of the NLRP3 and AIM2 Inflammasomes by Mambwe, Bezaleel, Neo, Kurt, Javanmard Khameneh, Hanif, Leong, Keith Weng Kit, Colantuoni, Mariasilvia, Vacca, Maurizio, Muimo, Richmond, Mortellaro, Alessandra

    Published in Frontiers in immunology (05-07-2019)
    “…The inflammasome is an intracellular multi-protein complex that orchestrates the release of the pro-inflammatory cytokines IL-1β and IL-18, and a form of cell…”
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    Journal Article
  2. 2

    Salmonella typhimurium-induced IL-1 release from primary human monocytes requires NLRP3 and can occur in the absence of pyroptosis by Diamond, Catherine E., Leong, Keith Weng Kit, Vacca, Maurizio, Rivers-Auty, Jack, Brough, David, Mortellaro, Alessandra

    Published in Scientific reports (31-07-2017)
    “…Large molecular complexes known as inflammasomes regulate the release of IL-1β from immune cells in response to infection and injury. Salmonella typhimurium…”
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    Journal Article
  3. 3

    Visualising cancer in 3D: 3‐Dimensional Tissue Imaging for management of cutaneous basal cell carcinoma by Tan, Yingrou, Zhang, Yuning, Li, Jackson Liang Yao, Chia, Hui Yi, Tan, Melissa Wee Ping, Ebel, Gernot, Leong, Keith Weng Kit, Lim, Eiffer Ying Qi, Chong, Kylia Kai Ling, Lee, Bernett Teck Kwong, Ng, Lai Guan, Tey, Hong Liang

    Published in Experimental dermatology (01-06-2024)
    “…Surgical management of basal cell carcinoma (BCC) typically involves surgical excision with post‐operative margin assessment using the bread‐loafing technique;…”
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  4. 4

    The Inflammasome Adaptor ASC Intrinsically Limits CD4 + T-Cell Proliferation to Help Maintain Intestinal Homeostasis by Javanmard Khameneh, Hanif, Leong, Keith Weng Kit, Mencarelli, Andrea, Vacca, Maurizio, Mambwe, Bezaleel, Neo, Kurt, Tay, Alice, Zolezzi, Francesca, Lee, Bernett, Mortellaro, Alessandra

    Published in Frontiers in immunology (15-07-2019)
    “…The inflammasome is a multi-protein complex that mediates proteolytic cleavage and release of the pro-inflammatory cytokines IL-1β and IL-18, and pyroptosis-a…”
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    Journal Article
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  6. 6

    An Immunoregulatory Role for Complement Receptors in Murine Models of Breast Cancer by Akhir, Fazrena Nadia Md, Noor, Mohd Hezmee Mohd, Leong, Keith Weng Kit, Nabizadeh, Jamileh A, Manthey, Helga D, Sonderegger, Stefan E, Fung, Jenny Nga Ting, McGirr, Crystal E, Shiels, Ian A, Mills, Paul C, Woodruff, Trent M, Rolfe, Barbara E

    Published in Antibodies (Basel) (08-01-2021)
    “…The complement system has demonstrated roles in regulating tumor growth, although these may differ between tumor types. The current study used two murine…”
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