Search Results - "Leong, Jeffrey W."

Cytokine activation induces human memory-like NK cells by Romee, Rizwan, Schneider, Stephanie E., Leong, Jeffrey W., Chase, Julie M., Keppel, Catherine R., Sullivan, Ryan P., Cooper, Megan A., Fehniger, Todd A.

“…Natural killer (NK) cells are lymphocytes that play an important role in the immune response to infection and malignancy. Recent studies in mice have shown…”
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Cytokine-induced memory-like natural killer cells exhibit enhanced responses against myeloid leukemia by Romee, Rizwan, Rosario, Maximillian, Berrien-Elliott, Melissa M, Wagner, Julia A, Jewell, Brea A, Schappe, Timothy, Leong, Jeffrey W, Abdel-Latif, Sara, Schneider, Stephanie E, Willey, Sarah, Neal, Carly C, Yu, Liyang, Oh, Stephen T, Lee, Yi-Shan, Mulder, Arend, Claas, Frans, Cooper, Megan A, Fehniger, Todd A

“…Natural killer (NK) cells are an emerging cellular immunotherapy for patients with acute myeloid leukemia (AML); however, the best approach to maximize NK cell…”
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CD56bright NK cells exhibit potent antitumor responses following IL-15 priming by Wagner, Julia A, Rosario, Maximillian, Romee, Rizwan, Berrien-Elliott, Melissa M, Schneider, Stephanie E, Leong, Jeffrey W, Sullivan, Ryan P, Jewell, Brea A, Becker-Hapak, Michelle, Schappe, Timothy, Abdel-Latif, Sara, Ireland, Aaron R, Jaishankar, Devika, King, Justin A, Vij, Ravi, Clement, Dennis, Goodridge, Jodie, Malmberg, Karl-Johan, Wong, Hing C, Fehniger, Todd A

“…NK cells, lymphocytes of the innate immune system, are important for defense against infectious pathogens and cancer. Classically, the CD56dim NK cell subset…”
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microRNA management of NK‐cell developmental and functional programs by Leong, Jeffrey W., Sullivan, Ryan P., Fehniger, Todd A.

“…NK cells are innate lymphoid cells that are critical for host defense against infection, and mediate anti‐tumor responses. MicroRNAs (miRNAs) are a large…”
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MicroRNA-142 Is Critical for the Homeostasis and Function of Type 1 Innate Lymphoid Cells by Berrien-Elliott, Melissa M., Sun, Yaping, Neal, Carly, Ireland, Aaron, Trissal, Maria C., Sullivan, Ryan P., Wagner, Julia A., Leong, Jeffrey W., Wong, Pamela, Mah-Som, Annelise Y., Wong, Terrence N., Schappe, Timothy, Keppel, Catherine R., Cortez, Victor S., Stamatiades, Efstathios G., Li, Ming O., Colonna, Marco, Link, Daniel C., French, Anthony R., Cooper, Megan A., Wang, Wei-Le, Boldin, Mark P., Reddy, Pavan, Fehniger, Todd A.

“…Natural killer (NK) cells are cytotoxic type 1 innate lymphoid cells (ILCs) that defend against viruses and mediate anti-tumor responses, yet mechanisms…”
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Utilizing Cytokines to Function-Enable Human NK Cells for the Immunotherapy of Cancer by Romee, Rizwan, Fehniger, Todd A., Leong, Jeffrey W.

“…Natural killer (NK) cells are innate lymphoid cells important for host defense against pathogens and mediate antitumor immunity. Cytokine receptors transduce…”
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Next-generation sequencing identifies the natural killer cell microRNA transcriptome by Fehniger, Todd A, Wylie, Todd, Germino, Elizabeth, Leong, Jeffrey W, Magrini, Vincent J, Koul, Sunita, Keppel, Catherine R, Schneider, Stephanie E, Koboldt, Daniel C, Sullivan, Ryan P, Heinz, Michael E, Crosby, Seth D, Nagarajan, Rakesh, Ramsingh, Giridharan, Link, Daniel C, Ley, Timothy J, Mardis, Elaine R

“…Natural killer (NK) cells are innate lymphocytes important for early host defense against infectious pathogens and surveillance against malignant…”
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PTEN regulates natural killer cell trafficking in vivo by Leong, Jeffrey W., Schneider, Stephanie E., Sullivan, Ryan P., Parikh, Bijal A., Anthony, Bryan A., Singh, Anvita, Jewell, Brea A., Schappe, Timothy, Wagner, Julia A., Link, Daniel C., Yokoyama, Wayne M., Fehniger, Todd A.

“…Significance Natural killer (NK) cells are critical players in the response to viruses and transformed cells, but the molecular mechanisms controlling their…”
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The IL-15-Based ALT-803 Complex Enhances FcγRIIIa-Triggered NK Cell Responses and In Vivo Clearance of B Cell Lymphomas by Rosario, Maximillian, Liu, Bai, Kong, Lin, Collins, Lynne I, Schneider, Stephanie E, Chen, Xiaoyue, Han, Kaiping, Jeng, Emily K, Rhode, Peter R, Leong, Jeffrey W, Schappe, Timothy, Jewell, Brea A, Keppel, Catherine R, Shah, Keval, Hess, Brian, Romee, Rizwan, Piwnica-Worms, David R, Cashen, Amanda F, Bartlett, Nancy L, Wong, Hing C, Fehniger, Todd A

“…Anti-CD20 monoclonal antibodies (mAb) are an important immunotherapy for B-cell lymphoma, and provide evidence that the immune system may be harnessed as an…”
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MicroRNA-146a deficiency enhances host protection against murine cytomegalovirus by Wong, Pamela, Leong, Jeffrey W, Sohn, Hyogon, Chang, Lily, Keppel, Catherine R, Neal, Carly C, Cubitt, Celia C, Yao, Tony, Keppel, Molly P, Tran, Jennifer, Burdi, Allison, Hwang, Kimberly, Fogel, Leslie A, Schappe, Timothy, Marsala, Lynne, Berrien-Elliott, Melissa M, Wagner, Julia A, Schneider, Stephanie E, Sullivan, Ryan P, Pingel, Jeanette T, Cooper, Megan A, French, Anthony R, Fehniger, Todd A

“…Natural killer (NK) cells are innate lymphoid cells that protect a host from viral infections and malignancies. MicroRNA-146a (miR-146a) is an important…”
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Transcriptional and post-transcriptional regulation of NK cell development and function by Leong, Jeffrey W, Wagner, Julia A, Ireland, Aaron R, Fehniger, Todd A

“…Abstract Natural killer (NK) cells are specialized innate lymphoid cells that survey against viral infections and malignancy. Numerous advances have improved…”
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MicroRNA-15/16 Antagonizes Myb To Control NK Cell Maturation by Sullivan, Ryan P, Leong, Jeffrey W, Schneider, Stephanie E, Ireland, Aaron R, Berrien-Elliott, Melissa M, Singh, Anvita, Schappe, Timothy, Jewell, Brea A, Sexl, Veronika, Fehniger, Todd A

“…NK cells develop in the bone marrow and complete their maturation in peripheral organs, but the molecular events controlling maturation are incompletely…”
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MicroRNA-deficient NK cells exhibit decreased survival but enhanced function by Sullivan, Ryan P, Leong, Jeffrey W, Schneider, Stephanie E, Keppel, Catherine R, Germino, Elizabeth, French, Anthony R, Fehniger, Todd A

“…NK cells are innate immune lymphocytes important for early host defense against infectious pathogens and malignant transformation. MicroRNAs (miRNAs) are small…”
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MicroRNA-155 tunes both the threshold and extent of NK cell activation via targeting of multiple signaling pathways by Sullivan, Ryan P, Fogel, Leslie A, Leong, Jeffrey W, Schneider, Stephanie E, Wong, Rachel, Romee, Rizwan, Thai, To-Ha, Sexl, Veronika, Matkovich, Scot J, Dorn, 2nd, Gerald W, French, Anthony R, Fehniger, Todd A

“…NK cells are innate lymphocytes important for host defense against viral infections and malignancy. However, the molecular programs orchestrating NK cell…”
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MicroRNA regulation of natural killer cells by Sullivan, Ryan P, Leong, Jeffrey W, Fehniger, Todd A

“…Natural killer (NK) cells are innate immune lymphocytes critical for host defense against viral infection and surveillance against malignant transformation…”
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Human NK cells: SET to kill by Leong, Jeffrey W., Fehniger, Todd A.

“…In this issue of Blood, Trotta et al define a novel mechanism of human granzyme B and perforin regulation and identify 2 new signaling players involved in…”
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Preactivation with IL-12, IL-15, and IL-18 Induces CD25 and a Functional High-Affinity IL-2 Receptor on Human Cytokine-Induced Memory-like Natural Killer Cells by Leong, Jeffrey W, Chase, Julie M, Romee, Rizwan, Schneider, Stephanie E, Sullivan, Ryan P, Cooper, Megan A, Fehniger, Todd A

“…Abstract Natural killer (NK) cells are effector lymphocytes that are under clinical investigation for the adoptive immunotherapy of hematologic malignancies,…”
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In Vivo Role of Flt3 Ligand and Dendritic Cells in NK Cell Homeostasis by Guimond, Martin, Freud, Aharon G, Mao, Hsiaoyin C, Yu, Jianhua, Blaser, Bradley W, Leong, Jeffrey W, Vandeusen, Jeffrey B, Dorrance, Adrienne, Zhang, Jianying, Mackall, Crystal L, Caligiuri, Michael A

“…IL-15 is required for NK cell development and homeostasis in vivo. Because IL-15 is presented in trans via its high-affinity IL-15Ralpha-chain to cells…”
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Natural Killer Cell Regulation by MicroRNAs in Health and Disease by Leong, Jeffrey W., Sullivan, Ryan P., Fehniger, Todd A.

“…Natural killer (NK) cells are innate immune lymphocytes that are critical for normal host defense against infections and mediate antitumor immune responses…”
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Management of the American Heart Association's guidelines for orthodontic treatment of patients at risk for infective endocarditis by Leong, Jeffrey W, Kunzel, Carol, Cangialosi, Thomas J

“…Introduction For over 50 years, the American Heart Association has made recommendations for the prevention of infective endocarditis. The first guidelines were…”
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