Search Results - "Leong, Denise E"

An Oct4‐Sall4‐Nanog network controls developmental progression in the pre‐implantation mouse embryo by Tan, Meng How, Au, Kin Fai, Leong, Denise E, Foygel, Kira, Wong, Wing H, Yao, Mylene WM

“…Landmark events occur in a coordinated manner during pre‐implantation development of the mammalian embryo, yet the regulatory network that orchestrates these…”
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Maternally and zygotically provided Cdx2 have novel and critical roles for early development of the mouse embryo by Jedrusik, Agnieszka, Bruce, Alexander W., Tan, Meng H., Leong, Denise E., Skamagki, Maria, Yao, Mylene, Zernicka-Goetz, Magdalena

“…Divisions of polarised blastomeres that allocate polar cells to outer and apolar cells to inner positions initiate the first cell fate decision in the mouse…”
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A novel and critical role for Oct4 as a regulator of the maternal-embryonic transition by Foygel, Kira, Choi, Bokyung, Jun, Sunny, Leong, Denise E, Lee, Alan, Wong, Connie C, Zuo, Elizabeth, Eckart, Michael, Reijo Pera, Renee A, Wong, Wing H, Yao, Mylene W M

“…Compared to the emerging embryonic stem cell (ESC) gene network, little is known about the dynamic gene network that directs reprogramming in the early embryo…”
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A Transgenic Mouse Model for High Content, Cell Cycle Phenotype Screening in Live Primary Cells by Burney, Richard O., Lee, Alan I., Leong, Denise E., Jones, Joshua T., Hahn, Angela T., Meyer, Tobias, Yao, Mylene W.M.

“…High content cell-based genetic and small molecule library screens are powerful strategies in drug discovery and investigations of disease mechanisms. We…”
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Comparison of epigenetic mediator expression and function in mouse and human embryonic blastomeres by Chavez, Shawn L, McElroy, Sohyun L, Bossert, Nancy L, De Jonge, Christopher J, Rodriguez, Maria Vera, Leong, Denise E, Behr, Barry, Westphal, Lynn M, Reijo Pera, Renee A

“…A map of human embryo development that combines imaging, molecular, genetic and epigenetic data for comparisons to other species and across pathologies would…”
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In vitro embryo culture in defined, sub‐microliter volumes by Melin, Jessica, Lee, Alan, Foygel, Kira, Leong, Denise E., Quake, Stephen R., Yao, Mylene W.M.

“…The high attrition rate of in vitro human embryo culture presents a major obstacle in the treatment of clinical infertility by in vitro fertilization (IVF)…”
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