Search Results - "Leonetti, F."
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Long-term effects of laparoscopic sleeve gastrectomy, gastric bypass, and adjustable gastric banding on type 2 diabetes
Published in Surgical endoscopy (01-05-2010)“…Background This study aimed to compare the efficacy of laparoscopic sleeve gastrectomy (SG) with that of laparoscopic gastric bypass (GBP) and laparoscopic…”
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Weight Regain and Diabetes Evolution After Sleeve Gastrectomy: a Cohort Study with over 5 Years of Follow-Up
Published in Obesity surgery (01-03-2020)“…Background A number of meta-analyses have demonstrated the effectiveness of bariatric surgery in improving morbid obesity and its associated co-morbidities…”
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Morbid obesity exposes the association between PNPLA3 I148M (rs738409) and indices of hepatic injury in individuals of European descent
Published in International Journal of Obesity (01-01-2010)“…Context: The PNPLA3 I148M variant (rs738409) is robustly associated with hepatic steatosis. Intriguingly, initial findings in cohorts with a mean body mass…”
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First-phase insulin secretion, insulin sensitivity, ghrelin, GLP-1, and PYY changes 72 h after sleeve gastrectomy in obese diabetic patients: the gastric hypothesis
Published in Surgical endoscopy (01-11-2011)“…Background The aim of this study was to evaluate the possible role of sleeve gastrectomy (SG) per se in the reversibility of diabetes. Methods Insulin…”
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Targeting monoamine oxidases with multipotent ligands: an emerging strategy in the search of new drugs against neurodegenerative diseases
Published in Current medicinal chemistry (01-10-2011)“…The socioeconomic burden of multi-factorial pathologies, such as neurodegenerative diseases (NDs), is enormous worldwide. Unfortunately, no proven…”
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Effectiveness of oral semaglutide on glucose control and body weight up to 18 months: a multicenter retrospective real-world study
Published in Journal of endocrinological investigation (01-06-2024)“…Aim Oral semaglutide, an innovative orally administered GLP-1 receptor agonist for type 2 diabetes (T2D) management was herein evaluated for its effectiveness…”
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Mapping ligand binding pockets in chloride ClC‐1 channels through an integrated in silico and experimental approach using anthracene‐9‐carboxylic acid and niflumic acid
Published in British journal of pharmacology (01-05-2018)“…Background and Purpose Although chloride channels are involved in several physiological processes and acquired diseases, the availability of compounds…”
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Blood glucose and epicardial adipose tissue at the hospital admission as possible predictors for COVID-19 severity
Published in Endocrine (01-01-2022)“…Purpose To study the possible association of CT-derived quantitative epicardial adipose tissue (EAT) and glycemia at the admission, with severe outcomes in…”
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Metabolic syndrome and adipose tissue: new clinical aspects and therapeutic targets
Published in Current pharmaceutical design (01-07-2007)“…The metabolic syndrome is a long-term process, explained by the interaction of genetic and environmental factors, that starts early in life and is involved in…”
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Quality of life and treatment satisfaction in adults with Type 1 diabetes: a comparison between continuous subcutaneous insulin infusion and multiple daily injections
Published in Diabetic medicine (01-02-2008)“…Aims The aim of this case–control study was to compare quality of life (QoL) and treatment satisfaction in adults with Type 1 diabetes (T1DM) treated with…”
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A uniform estimate for positive solutions of semilinear elliptic equations
Published in Transactions of the American Mathematical Society (01-08-2011)“…size of the domain that implies the existence of a positive solution satisfying a uniform pointwise estimate. Here uniform means that the estimate is…”
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The vitamin D receptor (VDR) gene rs11568820 variant is associated with type 2 diabetes and impaired insulin secretion in Italian adult subjects, and associates with increased cardio-metabolic risk in children
Published in Nutrition, metabolism, and cardiovascular diseases (01-05-2016)“…Abstract Background and aims 1α,25-dihydroxyvitamin-D3, the biologically active vitamin D, plays a central role in several metabolic pathways through the…”
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TSH levels are associated with vitamin D status and seasonality in an adult population of euthyroid adults
Published in Clinical and experimental medicine (01-08-2015)“…A circannual periodicity in thyrotropin (TSH) secretion has been reported but the causes of these phenomenon are still undefined. Vitamin D exerts a direct…”
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ANGPTL4 gene E40K variation protects against obesity‐associated dyslipidemia in participants with obesity
Published in Obesity science & practice (01-02-2019)“…Summary Objective ANGPTL4 inhibits lipoprotein lipase in adipose tissue, regulating plasma triglycerides levels. In persons with obesity plasma ANGPTL4 levels…”
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Laparoscopic Gastric Sleeve and Micronutrients Supplementation: Our Experience
Published in Journal of Obesity (01-01-2012)“…Background. Laparoscopic gastric sleeve (LGS) has been recently introduced as a stand-alone, restrictive bariatric surgery. Theoretically, LGS attenuates…”
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Coumarins Derivatives as Dual Inhibitors of Acetylcholinesterase and Monoamine Oxidase
Published in Journal of medicinal chemistry (13-09-2001)“…A set of 17 coumarin and 2 chromone derivatives with known inhibitory activity toward monoamine oxidase (MAO) A and B were tested as acetylcholinesterase…”
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Peripheral nociceptor sensitization mediates allodynia in patients with distal symmetric polyneuropathy
Published in Journal of neurology (01-03-2013)“…Patients with painful neuropathy frequently complain of pain in response to normally non-painful brushing, namely dynamic mechanical allodynia. Despite many…”
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BCR-ABL inhibitors in chronic myeloid leukemia: process chemistry and biochemical profile
Published in Current medicinal chemistry (01-06-2011)“…Chronic myeloid leukemia (CML) is a myeloproliferative disease originating from a constitutively active tyrosine kinase, called BCR-ABL, expressed by an…”
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Inhibition of Monoamine Oxidases by Functionalized Coumarin Derivatives: Biological Activities, QSARs, and 3D-QSARs
Published in Journal of medicinal chemistry (14-12-2000)“…A large series of coumarin derivatives (71 compounds) were tested for their monoamine oxidase A and B (MAO-A and MAO-B) inhibitory activity. Most of the…”
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