Search Results - "Leonardo De Freitas, Renato"

Cannabidiol in the dorsal hippocampus attenuates emotional and cognitive impairments related to neuropathic pain: The role of prelimbic neocortex-hippocampal connections by Medeiros, Ana Carolina, Medeiros, Priscila, Pigatto, Glauce Regina, Maione, Sabatino, Coimbra, Norberto Cysne, de Freitas, Renato Leonardo

“…Chronic neuropathic pain (NP) is commonly associated with cognitive and emotional impairments. Cannabidiol (CBD) presents a broad spectrum of action with a…”
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The scientific publication becomes more extensive than the article - BrJP data repository by Souza, Juliana Barcellos de, Freitas, Renato Leonardo de

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Connexions between the dorsomedial division of the ventromedial hypothalamus and the dorsal periaqueductal grey matter are critical in the elaboration of hypothalamically mediated panic-like behaviour by Ullah, Farhad, dos Anjos-Garcia, Tayllon, Mendes-Gomes, Joyce, Elias-Filho, Daoud Hibrahim, Falconi-Sobrinho, Luiz Luciano, Freitas, Renato Leonardo de, Khan, Asmat Ullah, Oliveira, Ricardo de, Coimbra, Norberto Cysne

“…The chemical stimulation of the dorsomedial division of the ventromedial hypothalamic nucleus (dmVMH) with NMDA at 9nmol elicits panic-like behavioural…”
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Infralimbic medial prefrontal cortex alters electroacupuncture effect in animals with neuropathic chronic pain by Leite Ferreira, Laís, Pereira Generoso, Laura, Medeiros, Ana Carolina, de Medeiros, Priscila, Leonardo de Freitas, Renato, Lourenço da Silva, Marcelo, Resende Torres da Silva, Josie

“…Morphological reorganization in the neural networks of the medial prefrontal cortex (mPFC) may be involved in the development of chronic neuropathic pain (NP)…”
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Neuroethological validation of an experimental apparatus to evaluate oriented and non-oriented escape behaviours: Comparison between the polygonal arena with a burrow and the circular enclosure of an open-field test by Biagioni, Audrey Francisco, Anjos-Garcia, Tayllon dos, Ullah, Farhad, Fisher, Isaac René, Falconi-Sobrinho, Luiz Luciano, Freitas, Renato Leonardo de, Felippotti, Tatiana Tocchini, Coimbra, Norberto Cysne

“…•Blockade of GABAA receptors in DMH, PH and dPAG evokes defensive behavioural response.•Bicuculline treatment into the DMH and PH induces oriented…”
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The endogenous opioid system modulates defensive behavior evoked by Crotalus durissus terrificus: Panicolytic-like effect of intracollicular non-selective opioid receptors blockade by Calvo, Fabrício, Lobão-Soares, Bruno, de Freitas, Renato Leonardo, Paschoalin-Maurin, Tatiana, dos Anjos-Garcia, Tayllon, Medeiros, Priscila, da Silva, Juliana Almeida, Lovick, Thelma Anderson, Coimbra, Norberto Cysne

“…Background: There is a controversy regarding the key role played by opioid peptide neurotransmission in the modulation of panic-attack-related responses. Aims:…”
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Involvement of prelimbic medial prefrontal cortex in panic-like elaborated defensive behaviour and innate fear-induced antinociception elicited by GABAA receptor blockade in the dorsomedial and ventromedial hypothalamic nuclei: role of the endocannabinoid CB1 receptor by de Freitas, Renato Leonardo, Salgado-Rohner, Carlos José, Hallak, Jaime Eduardo Cecílio, de Souza Crippa, José Alexandre, Coimbra, Norberto Cysne

“…It has been shown that GABAA receptor blockade in the dorsomedial and ventromedial hypothalamic nuclei (DMH and VMH, respectively) induces elaborated defensive…”
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Endogenous opioid peptide-mediated neurotransmission in central and pericentral nuclei of the inferior colliculus recruits μ1 -opioid receptor to modulate post-ictal antinociception by Felippotti, Tatiana Tocchini, Freitas, Renato Leonardo de, Coimbra, Norberto Cysne

“…Abstract Background The aim of the present work was to investigate the involvement of the μ1 -endogenous opioid peptide receptor-mediated system in post-ictal…”
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Nitric oxide-signalling affects panic-like defensive behaviour and defensive antinociception neuromodulation in the prelimbic cerebral cortex by de Freitas, Renato Leonardo, Acunha, Renata Moreira, Bendaña-Córdoba, Fernando René, Medeiros, Priscila, Melo-Thomas, Liana, Coimbra, Norberto Cysne

“…Effect of microinjection of either NPLA (NOS inhibitor) or c-PTIO (NO scavenger) in the prelimbic division (PrL) of the medial prefrontal cortex (mPFC),…”
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CB1-cannabinoid-, TRPV1-vanilloid- and NMDA-glutamatergic-receptor-signalling systems interact in the prelimbic cerebral cortex to control neuropathic pain symptoms by Medeiros, Priscila, Oliveira-Silva, Mariana, Negrini-Ferrari, Sylmara Esther, Medeiros, Ana Carolina, Elias-Filho, Daoud Hibraim, Coimbra, Norberto Cysne, de Freitas, Renato Leonardo

“…[Display omitted] •PrL cortex is connected to dorsal thalamus nuclei related to pain control.•PrL cortex potentiated mechanical allodynia by NMDA and TRPV1…”
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A publicação científica torna-se maior que o artigo - repositório de dados da BrJP by Souza, Juliana Barcellos de, Freitas, Renato Leonardo de

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Characterization of the sensory, affective, cognitive, biochemical, and neuronal alterations in a modified chronic constriction injury model of neuropathic pain in mice by Medeiros, Priscila, Freitas, Renato Leonardo, Boccella, Serena, Iannotta, Monica, Belardo, Carmela, Mazzitelli, Mariacristina, Romano, Rosaria, De Gregorio, Danilo, Coimbra, Norberto Cysne, Palazzo, Enza, Maione, Sabatino

“…The chronic constriction injury (CCI) of the sciatic nerve is a nerve injury‐based model of neuropathic pain (NP). Comorbidities of NP such as depression,…”
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N-methyl-d-aspartate Receptors in the Prelimbic Cortex are Critical for the Maintenance of Neuropathic Pain by Medeiros, Priscila, Negrini-Ferrari, Sylmara Esther, Palazzo, Enza, Maione, Sabatino, Ferreira, Sérgio Henrique, de Freitas, Renato Leonardo, Coimbra, Norberto Cysne

“…The mechanisms underlying chronic and neuropathic pain pathology involve peripheral and central sensitisation. The medial prefrontal cortex (mPFC) seems to…”
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Effect of electrical and chemical (activation versus inactivation) stimulation of the infralimbic division of the medial prefrontal cortex in rats with chronic neuropathic pain by Moura-Pacheco, Thais Lohanny, Martins-Pereira, Renata Cristina, Medeiros, Priscila, Sbragia, Lourenço, Ramos Andrade Leite-Panissi, Christie, Machado, Hélio Rubens, Coimbra, Norberto Cysne, de Freitas, Renato Leonardo

“…Neuropathic pain (NP) represents a complex disorder with sensory, cognitive, and emotional symptoms. The medial prefrontal cortex (mPFC) takes critical…”
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Cortical Neurostimulation and N-Methyl-D-Aspartate Glutamatergic Receptor Activation in the Dysgranular Layer of the Posterior Insular Cortex Modulate Chronic Neuropathic Pain by Martins Pereira, Renata Cristina, Medeiros, Priscila, Coimbra, Norberto Cysne, Machado, Hélio Rubens, de Freitas, Renato Leonardo

“…The dysgranula parts of the posterior insular cortex (PIC) stimulation (PICS) has been investigated as a new putative cortical target for nonpharmacologic…”
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The primary motor cortex electrical and chemical stimulation attenuates the chronic neuropathic pain by activation of the periaqueductal grey matter: The role of NMDA receptors by Negrini-Ferrari, Sylmara Esther, Medeiros, Priscila, Malvestio, Rafael Braghetto, de Oliveira Silva, Mariana, Medeiros, Ana Carolina, Coimbra, Norberto Cysne, Machado, Helio Rubens, de Freitas, Renato Leonardo

“…Effect of chemical (c) and electrical (e) stimulation in the primary (M1) motor cortex (MCS) on mechanical allodynia in chronic NP induced by adapted CCI of…”
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Mygalin, an Acanthoscurria gomesiana spider-derived synthetic, modulates haloperidol-induced cataleptic state in mice by Santos, Gabriela Xavier, Dos SantosTeodoro, Joyce Elise, Fonseca, Mylena Gonçalves, Acunha, Renata Moreira, da Silva Júnior, Pedro Ismael, Reis, Luciana Maria Dos, de Freitas, Renato Leonardo, Medeiros, Priscila

“…Haloperidol (HAL) is an antipsychotic used in the treatment of schizophrenia. However, adverse effects are observed in the extrapyramidal tracts due to its…”
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µ1-Opioid receptors in the dorsomedial and ventrolateral columns of the periaqueductal grey matter are critical for the enhancement of post-ictal antinociception by de Freitas, Renato Leonardo, Medeiros, Priscila, Khan, Asmat Ullah, Coimbra, Norberto Cysne

“…Generalised tonic and tonic–clonic seizures are followed by significant increase in nociceptive thresholds in both laboratory animals and humans. The…”
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An Adapted Chronic Constriction Injury of the Sciatic Nerve Produces Sensory, Affective, and Cognitive Impairments: A Peripheral Mononeuropathy Model for the Study of Comorbid Neuropsychiatric Disorders Associated with Neuropathic Pain in Rats by Medeiros, Priscila, dos Santos, Ieda Regina, Júnior, Ivair Matias, Palazzo, Enza, da Silva, José Aparecido, Machado, Hélio Rubens, Ferreira, Sérgio Henrique, Maione, Sabatino, Coimbra, Norberto Cysne, de Freitas, Renato Leonardo

“…Abstract Background Chronic constriction injury (CCI) is a model of neuropathic pain induced by four loose ligatures around the sciatic nerve. This work aimed…”
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Intraperitoneal cannabidiol attenuates neonatal germinal matrix hemorrhage-induced neuroinflamation and perilesional apoptosis by Abrantes De Lacerda Almeida, Timóteo, Santos, Marcelo Volpon, Da Silva Lopes, Luiza, Goel, Gunjan, Leonardo De Freitas, Renato, De Medeiros, Priscila, Crippa, José Alexandre, Machado, Hélio Rubens

“…Background. As the survival of preterm infants has increased significantly, germinal matrix hemorrhage (GMH) has become an important public health issue…”
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