Search Results - "Leonard, B"

The Warburg Effect Dictates the Mechanism of Butyrate-Mediated Histone Acetylation and Cell Proliferation by Donohoe, Dallas R., Collins, Leonard B., Wali, Aminah, Bigler, Rebecca, Sun, Wei, Bultman, Scott J.

“…Widespread changes in gene expression drive tumorigenesis, yet our knowledge of how aberrant epigenomic and transcriptome profiles arise in cancer cells is…”
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Covid-19 hyperinflammation and post-Covid-19 illness may be rooted in mast cell activation syndrome by Afrin, Lawrence B., Weinstock, Leonard B., Molderings, Gerhard J.

“…•Much of Covid-19 hyperinflammation is consistent with mast-cell-driven inflammation.•Prevalence of severe Covid-19 is similar to that of mast cell activation…”
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Posttranscriptional Control of T Cell Effector Function by Aerobic Glycolysis by Chang, Chih-Hao, Curtis, Jonathan D., Maggi, Leonard B., Faubert, Brandon, Villarino, Alejandro V., O’Sullivan, David, Huang, Stanley Ching-Cheng, van der Windt, Gerritje J.W., Blagih, Julianna, Qiu, Jing, Weber, Jason D., Pearce, Edward J., Jones, Russell G., Pearce, Erika L.

“…A “switch” from oxidative phosphorylation (OXPHOS) to aerobic glycolysis is a hallmark of T cell activation and is thought to be required to meet the metabolic…”
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Top advances of the year in colorectal cancer by Saltz, Leonard B.

“…Lay Summary Over the past year, studies have demonstrated better ways of using the agents that we have to improve outcomes for patients with colon and Rectal…”
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Biologics in the treatment of asthma in children and adolescents by Bacharier, Leonard B., Jackson, Daniel J.

“…Severe asthma in childhood confers substantial patient- and society-level burdens. Although biologics have been available for the management in adults and…”
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Azithromycin During Wheezing Illnesses Among Preschool Children - Does the Airway Microbiota Provide Insights into Mechanism? by Bacharier, Leonard B

“…Young children often experience recurrent episodes of respiratory tract illnesses manifested by wheezing, cough, and breathlessness. A substantial fraction of…”
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Association of respiratory allergy, asthma, and expression of the SARS-CoV-2 receptor ACE2 by Jackson, Daniel J., Busse, William W., Bacharier, Leonard B., Kattan, Meyer, O’Connor, George T., Wood, Robert A., Visness, Cynthia M., Durham, Stephen R., Larson, David, Esnault, Stephane, Ober, Carole, Gergen, Peter J., Becker, Patrice, Togias, Alkis, Gern, James E., Altman, Mathew C.

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The history of the "natural history" of hepatitis C (1968-2009) by Seeff, Leonard B.

“…In the late 1960's, only types A and B hepatitis were believed to exist, distinguished by circumstances of exposure and incubation periods. In the early…”
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Mentoring, Education, and Research: “A Push in the Right Direction ” by Kaban, Leonard B.

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Global Initiative for Asthma Strategy 2021: Executive Summary and Rationale for Key Changes by Reddel, Helen K, Bacharier, Leonard B, Bateman, Eric D, Brightling, Christopher E, Brusselle, Guy G, Buhl, Roland, Cruz, Alvaro A, Duijts, Liesbeth, Drazen, Jeffrey M, FitzGerald, J Mark, Fleming, Louise J, Inoue, Hiromasa, Ko, Fanny W, Krishnan, Jerry A, Levy, Mark L, Lin, Jiangtao, Mortimer, Kevin, Pitrez, Paulo M, Sheikh, Aziz, Yorgancioglu, Arzu A, Boulet, Louis-Philippe

“…The Global Initiative for Asthma (GINA) Strategy Report provides clinicians with an annually updated evidence-based strategy for asthma management and…”
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Tet Proteins Can Convert 5-Methylcytosine to 5-Formylcytosine and 5-Carboxylcytosine by Ito, Shinsuke, Shen, Li, Dai, Qing, Wu, Susan C., Collins, Leonard B., Swenberg, James A., He, Chuan, Zhang, Yi

“…5-methylcytosine (5mC) in DNA plays an important role in gene expression, genomic imprinting, and suppression of transposable elements. 5mC can be converted to…”
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Asthma guidelines: Where to next? by Bacharier, Leonard B.

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Eye Mobile Units and Their Effect on Access to Pediatric Eye Care by Nelson, Leonard B

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Acetate Promotes T Cell Effector Function during Glucose Restriction by Qiu, Jing, Villa, Matteo, Sanin, David E., Buck, Michael D., O’Sullivan, David, Ching, Reagan, Matsushita, Mai, Grzes, Katarzyna M., Winkler, Frances, Chang, Chih-Hao, Curtis, Jonathan D., Kyle, Ryan L., Van Teijlingen Bakker, Nikki, Corrado, Mauro, Haessler, Fabian, Alfei, Francesca, Edwards-Hicks, Joy, Maggi, Leonard B., Zehn, Dietmar, Egawa, Takeshi, Bengsch, Bertram, Klein Geltink, Ramon I., Jenuwein, Thomas, Pearce, Edward J., Pearce, Erika L.

“…Competition for nutrients like glucose can metabolically restrict T cells and contribute to their hyporesponsiveness during cancer. Metabolic adaptation to the…”
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FDA Approval of Tisagenlecleucel: Promise and Complexities of a $475 000 Cancer Drug by Bach, Peter B, Giralt, Sergio A, Saltz, Leonard B

“…Approval of the drug tisagenledeucel (Kymriah; Novartis) by the US Food and Drug Administration (FDA) for the treatment of pediatric and young adult acute…”
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Issues in Delivering Pediatric Eye Care to Financially Disadvantaged and Underrepresented Minority Groups by Nelson, Leonard B

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The Emergence of Female Pediatric Ophthalmologists Has Been Important and Necessary by Nelson, Leonard B

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An update on treatment of genotype 1 chronic hepatitis C virus infection: 2011 practice guideline by the American Association for the Study of Liver Diseases by Ghany, Marc G., Nelson, David R., Strader, Doris B., Thomas, David L., Seeff, Leonard B.

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Comprehensive Molecular Profiling of Intrahepatic and Extrahepatic Cholangiocarcinomas: Potential Targets for Intervention by Lowery, Maeve A, Ptashkin, Ryan, Jordan, Emmet, Berger, Michael F, Zehir, Ahmet, Capanu, Marinela, Kemeny, Nancy E, O'Reilly, Eileen M, El-Dika, Imane, Jarnagin, William R, Harding, James J, D'Angelica, Michael I, Cercek, Andrea, Hechtman, Jaclyn F, Solit, David B, Schultz, Nikolaus, Hyman, David M, Klimstra, David S, Saltz, Leonard B, Abou-Alfa, Ghassan K

“…Various genetic driver aberrations have been identified among distinct anatomic and clinical subtypes of intrahepatic and extrahepatic cholangiocarcinoma, and…”
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Our Hope for a Positive Change in the Economic and Workforce Issues in Pediatric Ophthalmology by Nelson, Leonard B

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