Search Results - "Leon, Rafael"

A new branch-and-filter exact algorithm for binary constraint satisfaction problems by San Segundo, Pablo, Furini, Fabio, León, Rafael

“…•We design and test an exact algorithm for binary constraint satisfaction problems.•The new algorithm efficiently exploits a reduction to the k-clique…”
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KEAP1‐NRF2 protein–protein interaction inhibitors: Design, pharmacological properties and therapeutic potential by Crisman, Enrique, Duarte, Pablo, Dauden, Esteban, Cuadrado, Antonio, Rodríguez‐Franco, María Isabel, López, Manuela G., León, Rafael

“…The transcription factor nuclear factor erythroid 2‐related factor 2 (NRF2) is considered the master regulator of the phase II antioxidant response. It…”
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Is Caffeine a Good Scavenger of Oxygenated Free Radicals? by León-Carmona, Jorge Rafael, Galano, Annia

“…The reactions of caffeine (CAF) with different reactive oxygen species (ROS) have been studied using density functional theory. Five mechanisms of reaction…”
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Phosphogypsum weathering and implications for pollutant discharge into an estuary by Millán-Becerro, Ricardo, Pérez-López, Rafael, Cánovas, Carlos R., Macías, Francisco, León, Rafael

“…[Display omitted] •The phosphogypsum pile behaves as a karstic-coastal aquifer with polluted groundwater.•The phosphogypsum stack is a continuous source of…”
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Inclusion complex of ITH12674 with 2-hydroxypropyl-β-cyclodextrin: Preparation, physical characterization and pharmacological effect by Michalska, Patrycja, Wojnicz, Aneta, Ruiz-Nuño, Ana, Abril, Sheila, Buendia, Izaskun, León, Rafael

“…•Preparation of ITH12674-HP-β-CD inclusion complex is described.•The Inclusion complex enhanced ITH12674 stability against pH and temperature.•The inclusion…”
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Singular Behavior of the Leading Lyapunov Exponent of a Product of Random 2×2 Matrices by Genovese, Giuseppe, Giacomin, Giambattista, Greenblatt, Rafael Leon

“…We consider a certain infinite product of random 2 × 2 matrices appearing in the solution of some 1 and 1 + 1 dimensional disordered models in statistical…”
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Towards circular and sustainable restoration of a deeply polluted river basin: The Odiel River catchment (SW Spain) by Millán-Becerro, Ricardo, León, Rafael, Romero-Matos, Jonatan, Moreno-González, Raul, Pérez-López, Rafael

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Innovative pathological network‐based multitarget approaches for Alzheimer's disease treatment by Mayo, Paloma, Pascual, Jorge, Crisman, Enrique, Domínguez, Cristina, López, Manuela G., León, Rafael

“…Alzheimer's disease (AD) is the most prevalent neurodegenerative disease and is a major health threat globally. Its prevalence is forecasted to exponentially…”
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Cetacean‐mediated vertical nitrogen transport in the oceanic realm by Woodstock, Matthew S., Kiszka, Jeremy J., Ramírez‐León, M. Rafael, Sutton, Tracey T., Fennel, Katja, Wang, Bin, Zhang, Yuying

“…In natural systems, animal‐mediated nutrient transport can be a major driver of primary productivity, but the role of marine megafauna such as cetaceans in…”
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Modeling Health Data Using Machine Learning Techniques Applied to Financial Management Predictions by Leon Sanz, Rafael, Leon-Sanz, Pilar

“…Health management has steadily improved in performance and accuracy using IT technology. Hospitals and health institutions hold an enormous number of data in…”
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Neuroprotective effect of melatonin against ischemia is partially mediated by alpha-7 nicotinic receptor modulation and HO-1 overexpression by Parada, Esther, Buendia, Izaskun, León, Rafael, Negredo, Pilar, Romero, Alejandro, Cuadrado, Antonio, López, Manuela G., Egea, Javier

“…Melatonin has been widely studied as a protective agent against oxidative stress. However, the molecular mechanisms underlying neuroprotection in…”
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Controlling π–π Interactions through Coordination Bond Formation: Assembly of 1‑D Chains of acac-Based Coordination Compounds by León-Zárate, Rafael, Valdés-Martínez, Jesús

“…We present a new approach for the construction of 1-D chains of acac-based copper coordination compounds assembled through π–π aromatic interactions. We use…”
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Origin of rare earth elements in acid mine drainage traced by strontium and neodymium isotopes by León, Rafael, Macías, Francisco, R. Cánovas, Carlos, Millán-Becerro, Ricardo, Romero-Matos, Jonatan, Nieto, José Miguel

“…Acid mine drainage (AMD) generated from coal and sulfide mining has attracted much interest due to the high concentrations of rare earth elements (REE)…”
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Effect of collectors of the puerulus of the southern rock lobster Jasus edwardsii (Hutton, 1875) (Decapoda: Achelata: Palinuridae) on lobster catch rates in Tasmania, Australia by Jayanti, Anes D, Gardner, Caleb, León, Rafael, Ogier, Emily, van Putten, Ingrid

“…ABSTRACT The harvesting of the puerulus of rock, or spiny, lobsters for seed for aquaculture is a large industry throughout the Indo-Pacific region, and an…”
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A distinctive rare earth element signature for pyrite oxidation and glacial weathering by Jang, Kwangchul, Bayon, Germain, Pourret, Olivier, Joe, Young Jin, Kim, Jung-Hyun, Byun, Eunji, Forwick, Matthias, León, Rafael, Nam, Seung-Il

“…The application of rare earth elements (REE) and neodymium (Nd) isotopes to authigenic Fe-(oxyhydr)oxide phases leached from marine sediments can be used for…”
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On the peroxyl scavenging activity of hydroxycinnamic acid derivatives: mechanisms, kinetics, and importance of the acid-base equilibrium by León-Carmona, Jorge Rafael, Alvarez-Idaboy, Juan Raúl, Galano, Annia

“…The peroxyl radical scavenging activity of four hydroxycinnamic acid derivatives (HCAD) has been studied in non-polar and aqueous solutions, using the density…”
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Wildfire effects on the hydrogeochemistry of a river severely polluted by acid mine drainage by Romero-Matos, Jonatan, Cánovas, Carlos R., Macías, Francisco, Pérez-López, Rafael, León, Rafael, Millán-Becerro, Ricardo, Nieto, Jose Miguel

“…•First research evaluating the wildfire effects in a deeply AMD-polluted watershed.•Temporal evolution of the hydrochemistry during the first rainfalls is…”
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Novel Multitarget Hybrid Compounds for the Treatment of Alzheimer's Disease by Michalska, Patrycja, Buendia, Izaskun, Del Barrio, Laura, Leon, Rafael

“…Alzheimer's disease (AD) is the most prevalent among the aging diseases known as neurodegenerative disorders. Drug design programs over the last two decades…”
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Empirically Fitted Parameters for Calculating pKa Values with Small Deviations from Experiments Using a Simple Computational Strategy by Galano, Annia, Pérez-González, Adriana, Castañeda-Arriaga, Romina, Muñoz-Rugeles, Leonardo, Mendoza-Sarmiento, Gabriela, Romero-Silva, Antonio, Ibarra-Escutia, Agustin, Rebollar-Zepeda, Aida Mariana, León-Carmona, Jorge Rafael, Hernández-Olivares, Manuel Alejandro, Alvarez-Idaboy, Juan Raúl

“…Two empirically fitted parameters have been derived for 74 levels of theory. They allow fast and reliable pKa calculations using only the Gibbs energy…”
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Mine waters as a secondary source of rare earth elements worldwide: The case of the Iberian Pyrite Belt by León, Rafael, Macías, Francisco, R. Cánovas, Carlos, Pérez-López, Rafael, Ayora, Carlos, Nieto, José Miguel, Olías, Manuel

“…Acid Mine Drainage (AMD) generates a great concern worldwide due to its severe impact to water resources during hundreds and even thousands of years after the…”
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