Search Results - "Leon, Luis M."

Recent developments in the cleavage, functionalization, and conjugation of proteins and peptides at tyrosine residues by Zhang, Shengping, De Leon Rodriguez, Luis M, Li, Freda F, Brimble, Margaret A

“…Peptide and protein selective modification at tyrosine residues has become an exploding field of research as tyrosine constitutes a robust alternative to…”
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Chemical Synthesis of Bioactive Naturally Derived Cyclic Peptides Containing Ene‐Like Rigidifying Motifs by De Leon Rodriguez, Luis M., Williams, Elyse T., Brimble, Margaret A.

“…The development of synthetic methods to prepare conformationally constrained peptides and peptide–polyketide hybrids remain an important chemical challenge. It…”
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Total Synthesis and Conformational Study of Callyaerin A: Anti‐Tubercular Cyclic Peptide Bearing a Rare Rigidifying (Z)‐2,3‐ Diaminoacrylamide Moiety by Zhang, Shengping, De Leon Rodriguez, Luis M., Leung, Ivanhoe K. H., Cook, Gregory M., Harris, Paul W. R., Brimble, Margaret A.

“…The first synthesis of the anti‐TB cyclic peptide callyaerin A (1), containing a rare (Z)‐2,3‐diaminoacrylamide bridging motif, is reported…”
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Quadratically Constrained Quadratic Programming Formulation of Contingency Constrained Optimal Power Flow with Photovoltaic Generation by Leon, Luis M., Bretas, Arturo S., Rivera, Sergio

“…Contingency Constrained Optimal Power Flow (CCOPF) differs from traditional Optimal Power Flow (OPF) because its generation dispatch is planned to work with…”
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Synthesis and bioactivity of antitubercular peptides and peptidomimetics: an update by De Leon Rodriguez, Luis M, Kaur, Harveen, Brimble, Margaret A

“…Mycobacterium tuberculosis is the causative agent of tuberculosis (TB), an infection that has been declared a global public health emergency by the World…”
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Structure-mechanical property correlations of hydrogel forming β-sheet peptides by De Leon Rodriguez, Luis M, Hemar, Yacine, Cornish, Jillian, Brimble, Margaret A

“…Peptide based hydrogels have received much attention due to their potential biomedical applications. The majority of the gel forming peptides present a β-sheet…”
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Synthesis of Natural Cyclopentapeptides Isolated from Dianthus chinensis by Zhang, Shengping, Amso, Zaid, De Leon Rodriguez, Luis M, Kaur, Harveen, Brimble, Margaret A

“…The first syntheses of the naturally occurring cyclic peptides dianthin I (1), pseudostellarin A (2), and heterophyllin J (3) are described. The linear…”
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Prospecting the applications and discovery of peptide hydrogels in food by De Leon Rodriguez, Luis M., Hemar, Yacine

“…The interest in peptide hydrogels of natural origin has dramatically increased given the potential applications in several fields -e.g. biomedicine and…”
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Basic MR relaxation mechanisms and contrast agent design by De León-Rodríguez, Luis M., Martins, André F., Pinho, Marco C., Rofsky, Neil M., Sherry, A. Dean

“…The diagnostic capabilities of magnetic resonance imaging (MRI) have undergone continuous and substantial evolution by virtue of hardware and software…”
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Noninvasive MRI of β-cell function using a Zn²⁺-responsive contrast agent by Lubag, Angelo J. M., De Leon-Rodriguez, Luis M., Burgess, Shawn C., Sherry, A. Dean

“…Elevation of postprandial glucose stimulates release of insulin from granules stored in pancreatic islet β-cells. We demonstrate here that divalent zinc ions…”
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Structure-Activity Relationships of Wollamide Cyclic Hexapeptides with Activity against Drug-Resistant and Intracellular Mycobacterium tuberculosis by Khalil, Zeinab G, Hill, Timothy A, De Leon Rodriguez, Luis M, Lohman, Rink-Jan, Hoang, Huy N, Reiling, Norbert, Hillemann, Doris, Brimble, Margaret A, Fairlie, David P, Blumenthal, Antje, Capon, Robert J

“…Wollamides are cyclic hexapeptides, recently isolated from an Australian soil isolate, that exhibit promising antimycobacterial activity against Bacille…”
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A novel tyrosine hyperoxidation enables selective peptide cleavage by Zhang, Shengping, De Leon Rodriguez, Luis M, Li, Freda F, Huang, Renjie, Leung, Ivanhoe K H, Harris, Paul W R, Brimble, Margaret A

“…A novel tyrosine hyperoxidation enabling selective peptide cleavage is reported. The scission of the N-terminal amide bond of tyrosine was achieved with…”
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An update on new methods to synthesize cyclotetrapeptides by De Leon Rodriguez, Luis M, Weidkamp, Andreas J, Brimble, Margaret A

“…Cyclotetrapeptides are important bioactive lead drug molecules that display a wide spectrum of pharmacological activities. However, the synthesis of…”
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The Synthesis and Chelation Chemistry of DOTA−Peptide Conjugates by De León-Rodríguez, Luis M, Kovacs, Zoltan

“…Metal complexes of DOTA (1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid)−peptide conjugates are increasingly used as targeted imaging and therapeutic…”
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Cyclization of Linear Tetrapeptides Containing N‐Methylated Amino Acids by using 1‐Propanephosphonic Acid Anhydride by Zhang, Shengping, De Leon Rodriguez, Luis M., Lacey, Ernest, Piggott, Andrew M., Leung, Ivanhoe K. H., Brimble, Margaret A.

“…The cyclization of the linear tetrapeptides sequence H‐NMePhe‐Xaa1‐NMePhe‐Xaa2‐OH (for which Xaa1 = Xaa2 = Ile, Val, or Leu; Xaa1 = Val; Xaa2 = Ile or Leu) by…”
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Multifunctional thermoresponsive designer peptide hydrogels by De Leon-Rodriguez, Luis M., Hemar, Yacine, Mo, Guang, Mitra, Alok K., Cornish, Jillian, Brimble, Margaret A.

“…[Display omitted] We report the synthesis and characterization of multifunctional peptides comprised of a hydrogel forming β-sheet peptide segment and a matrix…”
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Development of poly(vinylidene fluoride)/ionic liquid electrospun fibers for tissue engineering applications by Dias, Juliana C., Correia, Daniela C., Lopes, Ana C., Ribeiro, Sylvie, Ribeiro, Clarisse, Sencadas, Vitor, Botelho, Gabriela, Esperança, José M. S. S., Laza, José M., Vilas, José L., León, Luis M., Lanceros-Méndez, Senentxu

“…Electroactive electrospun fiber mat composites based on poly(vinylidene fluoride) (PVDF) with 5 and 10 % of 1-ethyl-3-methylimidazolium…”
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Cu-coated cellulose nanopaper for green and low-cost electronics by Lizundia, Erlantz, Delgado-Aguilar, Marc, Mutjé, Pere, Fernández, Eduardo, Robles-Hernandez, Beatriz, de la Fuente, María Rosario, Vilas, José Luis, León, Luis M.

“…In this work we have developed low-cost, renewable and sustainable materials based on cellulose for electronic applications. The UV–Vis spectroscopy, water…”
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Branched and ionic β-Cyclodextrins multilayer assembling onto polyacrylonitrile membranes for removal and controlled release of triclosan by Pérez-Álvarez, Leyre, Matas, Janire, Gómez-Galván, Flor, Ruiz-Rubio, Leire, León, Luis M., Vilas-Vilela, Jose Luis

“…•bβCDs polyelectrolyte multilayers were assembled onto hydrolyzed PAN membranes.•LbL assembling and degradation was monitored by XPS, FTIR and labelling with…”
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A New Gadolinium-Based MRI Zinc Sensor by Esqueda, Ana C., López, Jorge A., Andreu-de-Riquer, Gabriel, Alvarado-Monzón, José C., Ratnakar, James, Lubag, Angelo J. M., Sherry, A. Dean, De León-Rodríguez, Luis M.

“…The properties of a novel Gd3+-based MRI zinc sensor are reported. Unlike previously reported Gd3+-based MRI contrast agents, this agent (GdL) differs in that…”
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