Search Results - "Leon, Larry"

Safety and effectiveness of bevacizumab-containing treatment for non-small-cell lung cancer: final results of the ARIES observational cohort study by Lynch, Jr, Thomas J, Spigel, David R, Brahmer, Julie, Fischbach, Neal, Garst, Jennifer, Jahanzeb, Mohammad, Kumar, Priya, Vidaver, Regina M, Wozniak, Antoinette J, Fish, Susan, Flick, E Dawn, Leon, Larry, Hazard, Sebastien J, Kosty, Michael P

“…Bevacizumab, a recombinant humanized monoclonal antibody against vascular endothelial growth factor, was approved by the US Food and Drug Administration for…”
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A phase II trial of surgical resection and adjuvant high-dose hemithoracic radiation for malignant pleural mesothelioma by Rusch, Valerie W., Rosenzweig, Kenneth, Venkatraman, Ennapadam, Leon, Larry, Raben, Adam, Harrison, Louis, Bains, Manjit S., Downey, Robert J., Ginsberg, Robert J.

“…Background: Surgical resection of malignant pleural mesothelioma is reported to have up to an 80% rate of local recurrence. We performed a phase II trial of…”
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Identification of Prognostic Factors in Advanced Epithelial Ovarian Carcinoma by Chi, Dennis S., Liao, John B., Leon, Larry F., Venkatraman, Ennapadam S., Hensley, Martee L., Bhaskaran, Dharmendra, Hoskins, William J.

“…Objective. The Gynecologic Oncology Group (GOG) has demonstrated that age, tumor grade, and size and number of residual lesions after primary cytoreductive…”
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Exploratory subgroup identification in the heterogeneous Cox model: A relatively simple procedure by León, Larry F., Jemielita, Thomas, Guo, Zifang, Marceau West, Rachel, Anderson, Keaven M.

“…For survival analysis applications we propose a novel procedure for identifying subgroups with large treatment effects, with focus on subgroups where treatment…”
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The Hybridization Effects of Glass and Carbon Fibers on the Mechanical Properties of Kenaf Mat/Epoxy Composites by Malik, Khurshid, Ahmad, Faiz, Yunus, Nurul Azhani, Gunister, Ebru, Dawood, MSI Shaik, Ali, Saad, Mani, Catherine Sheila, Syahir, Muhammad, Larry, Anselm Leon

“…Kenaf mat/epoxy composite possesses low mechanical properties. The investigation examined the hybridization impact on the mechanical performance of kenaf…”
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Factors determining outcome after surgical resection of T3 and T4 lung cancers of the superior sulcus by Rusch, Valerie W., Parekh, Kalpaj R., Leon, Larry, Venkatraman, Ennapadam, Bains, Manjit S., Downey, Robert J., Boland, Patrick, Bilsky, Mark, Ginsberg, Robert J.

“…Background: The treatment of superior sulcus lung cancers is evolving and preoperative chemotherapy is increasingly used. To establish a historical benchmark…”
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Project management step-by-step by Richman, Larry

“…This volume explores the basics of implementing a project-management model and encourages critical thinking about how project management can help a company…”
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Estimation of treatment effects in weighted log-rank tests by Lin, Ray S, León, Larry F

“…Abstract Non-proportional hazards have been observed in clinical trials. The log-rank test loses power and the standard Cox model generally produces biased…”
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On Weighted Log-Rank Combination Tests and Companion Cox Model Estimators by León, Larry F., Lin, Ray, Anderson, Keaven M.

“…In randomized clinical trials, the log-rank test and Cox proportional hazards model are the gold standard in survival data analyses. While the log-rank test is…”
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Successful project management by Richman, Larry

“…Successful Project Management, Third Edition, covers the fundamentals of project management, focusing on practical skills you can apply immediately to complete…”
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Phase I and Pharmacokinetic Study of 10-Propargyl-10-deazaaminopterin, a New Antifolate by KRUG, Lee M, NG, Kenneth K, KRIS, Mark G, MILLER, Vincent A, TONG, William, HEELAN, Robert T, LEON, Larry, LEUNG, Denis, KELLY, Jean, SIROTNAK, F. M

“…The 10-deazaaminopterins are a new class of rationally designed antifolates demonstrating greater antitumor effects than methotrexate in murine tumor models…”
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MODEL CHECKING TECHNIQUES FOR ASSESSING FUNCTIONAL FORM SPECIFICATIONS IN CENSORED LINEAR REGRESSION MODELS by León, Larry F., Cai, Tianxi

“…In this paper we develop model checking techniques for assessing functional form specifications of covariates in censored linear regression models. These…”
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Improving your project management skills, second edition by Richman, Larry

“…Based on the bestselling American Management Association seminar! If a full-fledged project management course doesnÆt fit your schedule or your budget, check…”
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Successful Project Management, Third Edition by Richman, Larry L, Richman, Larry

“…Successful Project Management, Third Edition, covers the fundamentals of project management, focusing on practical skills you can apply immediately to complete…”
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Assessment of Model Adequacy for Markov Regression Time Series Models by Léon, Larry F., Tsai, Chih-Ling

“…In Markov regression models with time series data, we apply asymptotic results to obtain the quasi-score, quasi-Wald, and quasi-likelihood ratio tests for…”
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Bevacizumab maintenance in patients with advanced non-small-cell lung cancer, clinical patterns, and outcomes in the Eastern Cooperative Oncology Group 4599 Study: results of an exploratory analysis by Lopez-Chavez, Ariel, Young, Todd, Fages, Sophie, Leon, Larry, Schiller, Joan H, Dowlati, Afshin, Brahmer, Julie R, Johnson, David H, Sandler, Alan

“…The Eastern Cooperative Oncology Group (ECOG) 4599 study showed a significant survival benefit with the use of bevacizumab (BV) in combination with carboplatin…”
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Erlotinib after initial platinum-doublet chemotherapy in patients with epidermal growth factor receptor ( EGFR ) wild-type (WT) non-small cell lung cancer (NSCLC): Results of a combined patient-level analysis of the BR.21 and SATURN trials by Osarogiagbon, Raymond U, Cappuzzo, Federico, Ciuleanu, Tudor-Eliade, Leon, Larry

“…Abstract only 8080 Background: Two double-blind, prospective, randomized, placebo-controlled trials demonstrated survival benefit in unselected populations…”
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Isolating the Role of Bevacizumab in Elderly Patients With Previously Untreated Nonsquamous Non-Small Cell Lung Cancer: Secondary Analyses of the ECOG 4599 and PointBreak Trials by Langer, Corey J, Socinski, Mark A, Patel, Jyoti D, Sandler, Alan B, Schiller, Joan H, Leon, Larry, Hazard, Sebastien J, Ramalingam, Suresh S

“…Patient-level data from 2 phase III studies in patients with previously untreated, advanced-stage, nonsquamous non-small cell lung cancer (NSCLC) were pooled…”
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If the ratio of hazards r(t)=λe(t)/λc(t) does not depend on time t then the proportional hazards assumption holds by Leon, Larry Frank, Day, Bann-Mo, Hu, Xiaoping Sylvia

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Erlotinib therapy after initial platinum doublet therapy in patients with EGFR wild type non-small cell lung cancer: results of a combined patient-level analysis of the NCIC CTG BR.21 and SATURN trials by Osarogiagbon, Raymond U., Cappuzzo, Federico, Ciuleanu, Tudor, Leon, Larry, Klughammer, Barbara

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