Search Results - "Leon, Francisco"

The Polypharmacological Effects of Cannabidiol by Castillo-Arellano, Jorge, Canseco-Alba, Ana, Cutler, Stephen J, León, Francisco

“…Cannabidiol (CBD) is a major phytocannabinoid present in (Linneo, 1753). This naturally occurring secondary metabolite does not induce intoxication or exhibit…”
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Novel Approaches, Drug Candidates, and Targets in Pain Drug Discovery by Obeng, Samuel, Hiranita, Takato, León, Francisco, McMahon, Lance R, McCurdy, Christopher R

“…Because of the problems associated with opioids, drug discovery efforts have been employed to develop opioids with reduced side effects using approaches such…”
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Determination of the Optimal Switching Frequency for Distribution System Reconfiguration by Zhechao Li, Jazebi, Saeed, de Leon, Francisco

“…This paper shows that there is great potential for saving money when reconfiguring distribution systems at an optimal frequency. Studies are conducted on…”
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Perspective on the Therapeutics of Anti-Snake Venom by Gómez-Betancur, Isabel, Gogineni, Vedanjali, Salazar-Ospina, Andrea, León, Francisco

“…Snakebite envenomation is a life-threatening disease that was recently re-included as a neglected tropical disease (NTD), affecting millions of people in…”
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Effectiveness of an Inactivated SARS-CoV-2 Vaccine in Chile by Jara, Alejandro, Undurraga, Eduardo A, González, Cecilia, Paredes, Fabio, Fontecilla, Tomás, Jara, Gonzalo, Pizarro, Alejandra, Acevedo, Johanna, Leo, Katherinne, Leon, Francisco, Sans, Carlos, Leighton, Paulina, Suárez, Pamela, García-Escorza, Heriberto, Araos, Rafael

“…In a national prospective cohort study involving 10.2 million participants in Chile, the effectiveness of an inactivated SARS-CoV-2 vaccine, which had been…”
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Mitigation of Half-Cycle Saturation of Adjacent Transformers During HVDC Monopolar Operation-Part I: Mitigation Principle and Device Design by Yang, Ming, Deswal, Digvijay, de Leon, Francisco

“…When HVDC transmission systems operate in the ground return mode, transformers in adjacent ac systems frequently suffer half-cycle saturation. In this two-part…”
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Activity of Mitragyna speciosa (“Kratom”) Alkaloids at Serotonin Receptors by León, Francisco, Obeng, Samuel, Mottinelli, Marco, Chen, Yiming, King, Tamara I, Berthold, Erin C, Kamble, Shyam H, Restrepo, Luis F, Patel, Avi, Gamez-Jimenez, Lea R, Lopera-Londoño, Carolina, Hiranita, Takato, Sharma, Abhisheak, Hampson, Aidan J, Canal, Clinton E, McMahon, Lance R, McCurdy, Christopher R

“…Kratom alkaloids have mostly been evaluated for their opioid activity but less at other targets that could contribute to their physiological effects. Here, we…”
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Therapeutics to Treat Psychiatric and Neurological Disorders: A Promising Perspective from Algerian Traditional Medicine by Larit, Farida, León, Francisco

“…Ancient people sought out drugs in nature to prevent, cure, and treat their diseases, including mental illnesses. Plants were their primary source for meeting…”
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Antimicrobial Activity of Silver Nanoparticles in Polycaprolactone Nanofibers against Gram-Positive and Gram-Negative Bacteria by López-Esparza, Juan, Espinosa-Cristóbal, León Francisco, Donohue-Cornejo, Alejandro, Reyes-López, Simón Yobanny

“…Drug-resistance infections have increased extremely quickly in the past years, emerging as a serious health problem in the world. Novel and better…”
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Exploring the Chemistry of Alkaloids from Malaysian Mitragyna speciosa (Kratom) and the Role of Oxindoles on Human Opioid Receptors by Chear, Nelson Jeng-Yeou, León, Francisco, Sharma, Abhisheak, Kanumuri, Siva Rama Raju, Zwolinski, Grant, Abboud, Khalil A, Singh, Darshan, Restrepo, Luis F, Patel, Avi, Hiranita, Takato, Ramanathan, Surash, Hampson, Aidan J, McMahon, Lance R, McCurdy, Christopher R

“…Ten indole and oxindole alkaloids (1–10) were isolated from the freshly collected leaves of Malaysian Mitragyna speciosa (Kratom). The chemical structures of…”
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Controlling Non-Synchronous Microgrids for Load Balancing of Radial Distribution Systems by Tianqi Hong, de Leon, Francisco

“…This paper proposes a novel control strategy such that downstream non-synchronous microgrids can perform load balancing functions. The proposed method can…”
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The queen conch mitogenome: intra- and interspecific mitogenomic variability in Strombidae and phylogenetic considerations within the Hypsogastropoda by Machkour-M’Rabet, Salima, Hanes, Margaret M., Martínez-Noguez, Josué Jacob, Cruz-Medina, Jorge, García-De León, Francisco J.

“…Aliger gigas is an economically important and vulnerable marine species. We present a new mitogenome of A. gigas from the Mexican Caribbean and use the eight…”
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Theoretical and Experimental Verification of CVR Energy Savings for Refrigeration Loads by Behzadirafi, Shayan, Malallah, Yaaqoub, Qaseer, Layth, de Leon, Francisco

“…This paper presents analytical and experimental studies on Conservation Voltage Reduction (CVR) for Refrigeration Loads (RLs) driven by single-phase and…”
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Permanent Emergency LED Lamp Based on a Series Single-Switch Resonant Converter With Battery Clamp by Quintana-Barcia, Pablo, Ribas, Javier, Juarez-Leon, Francisco, Rodriguez-Fuertes, Diego

“…Permanent emergency lighting is a safety device whose lamp is always on and continues to operate when a mains failure occurs. The circuit has to charge the…”
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Genetic diversity and structure of circumtropical almaco jack, Seriola rivoliana: tool for conservation and management by Mendoza‐Portillo, Verónica, Galván‐Tirado, Carolina, Portnoy, David S., Valenzuela‐Quiñonez, Fausto, Domínguez‐Domínguez, Omar, Durand, Jean‐Dominique, Pérez‐Urbiola, Juan Carlos, García‐De León, Francisco J.

“…The almaco jack, Seriola rivoliana, is a circumtropical pelagic fish of importance both in commercial fisheries and in aquaculture. To understand levels of…”
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Directed Biosynthesis of Mitragynine Stereoisomers by Schotte, Carsten, Jiang, Yindi, Grzech, Dagny, Dang, Thu-Thuy T., Laforest, Larissa C., León, Francisco, Mottinelli, Marco, Nadakuduti, Satya Swathi, McCurdy, Christopher R., O’Connor, Sarah E.

“…Mitragyna speciosa (“kratom”) is used as a natural remedy for pain and management of opioid dependence. The pharmacological properties of kratom have been…”
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Using genome-wide diversity and population structure to define management units in the cirio (Fouquieria columnaris), an emblematic tree of the Sonoran Desert by Martínez-Noguez, Josué J., García-De León, Francisco J.

“…An important research goal for plant species of conservation concern is to identify and spatially delimit genetically distinct populations and understand their…”
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Detection of gluten immunogenic peptides in the urine of patients with coeliac disease reveals transgressions in the gluten-free diet and incomplete mucosal healing by Moreno, María de Lourdes, Cebolla, Ángel, Muñoz-Suano, Alba, Carrillo-Carrion, Carolina, Comino, Isabel, Pizarro, Ángeles, León, Francisco, Rodríguez-Herrera, Alfonso, Sousa, Carolina

“…Gluten-free diet (GFD) is the only management for coeliac disease (CD). Available methods to assess GFD compliance are insufficiently sensitive to detect…”
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Dynamic Thermal Model for Different Size Trefoil Power Cables With Various Loads in Non-Forced-Ventilated Tunnels by Giglio, David A., de Leon, Francisco

“…This paper presents a dynamic thermal model for trefoil cables of different sizes (and/or loads) installed in non-forced-ventilated tunnels. This is a step…”
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Pharmacokinetics of Eleven Kratom Alkaloids Following an Oral Dose of Either Traditional or Commercial Kratom Products in Rats by Kamble, Shyam H, Berthold, Erin C, King, Tamara I, Raju Kanumuri, Siva Rama, Popa, Raluca, Herting, Julius R, León, Francisco, Sharma, Abhisheak, McMahon, Lance R, Avery, Bonnie A, McCurdy, Christopher R

“…Kratom, Mitragyna speciosa Korth., is being widely consumed in the United States for pain management and the reduction of opioid withdrawal symptoms. The…”
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