Search Results - "Leon, Alberto Diaz de"
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Prospective performance of clear cell likelihood scores (ccLS) in renal masses evaluated with multiparametric magnetic resonance imaging
Published in European radiology (01-01-2021)“…Objectives Solid renal masses have unknown malignant potential with commonly utilized imaging. Biopsy can offer a diagnosis of cancer but has a high…”
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Diagnostic Performance and Interreader Agreement of a Standardized MR Imaging Approach in the Prediction of Small Renal Mass Histology
Published in Radiology (01-05-2018)“…Purpose To assess the diagnostic performance and interreader agreement of a standardized diagnostic algorithm in determining the histologic type of small (≤4…”
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Direct MRI-guided In-Bore Targeted Biopsy of the Prostate: A Step-by-Step How To and Lessons Learned
Published in Radiographics (01-02-2024)“…Multiparametric MRI-the most accurate imaging technique for detection of prostate cancer-has transformed the landscape of prostate cancer diagnosis by enabling…”
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Telomere lengths, pulmonary fibrosis and telomerase (TERT) mutations
Published in PloS one (19-05-2010)“…Telomerase is an enzyme that catalyzes the addition of nucleotides on the ends of chromosomes. Rare loss of function mutations in the gene that encodes the…”
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Subclinical Lung Disease, Macrocytosis, and Premature Graying in Kindreds With Telomerase ( TERT ) Mutations
Published in Chest (01-09-2011)“…Background Mutations in the human gene encoding the protein component of telomerase ( TERT ) are the most common genetic defect in patients with familial…”
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Safety and efficacy of concurrent immune checkpoint inhibitors and hypofractionated body radiotherapy
Published in Oncoimmunology (03-07-2018)“…Integration of hypofractionated body radiotherapy (H-RT) into immune checkpoint inhibitor (ICI) therapy may be a promising strategy to improve the outcomes of…”
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Rare prostate cancer mimic on multiparametric MRI: Cowper's gland hyperplasia
Published in Urology case reports (01-09-2021)“…Multiparametric MRI and targeted biopsies of the prostate have been increasingly utilized in men with elevated PSA. It is important to recognize potential…”
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Imaging and Screening of Kidney Cancer
Published in The Radiologic clinics of North America (01-11-2017)“…Renal cell carcinoma (RCC) exhibits a diverse and heterogeneous disease spectrum, but insight into its molecular biology has provided an improved understanding…”
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Role of Multiparametric MR Imaging in Malignancies of the Urogenital Tract
Published in Magnetic resonance imaging clinics of North America (01-02-2016)“…Multiparametric MR imaging (mpMRI) combine different sequences that, properly tailored, can provide qualitative and quantitative information about the tumor…”
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PD-L1 detection using 89Zr-atezolizumab immuno-PET in renal cell carcinoma tumorgrafts from a patient with favorable nivolumab response
Published in Journal for immunotherapy of cancer (03-06-2019)“…Background Programmed death-ligand 1 (PD-L1) expression in metastatic renal cell carcinoma (RCC) correlates with a worse prognosis, but whether it also…”
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Abbreviated‐protocol screening MRI vs. complete‐protocol diagnostic MRI for detection of hepatocellular carcinoma in patients with cirrhosis: An equivalence study using LI‐RADS v2018
Published in Journal of magnetic resonance imaging (01-02-2020)“…Background The high operational cost of MRI limits its utility for hepatocellular carcinoma (HCC) screening. Abbreviated‐protocol dynamic contrast‐enhanced MRI…”
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HIF-2 Complex Dissociation, Target Inhibition, and Acquired Resistance with PT2385, a First-in-Class HIF-2 Inhibitor, in Patients with Clear Cell Renal Cell Carcinoma
Published in Clinical cancer research (15-02-2020)“…The heterodimeric transcription factor HIF-2 is arguably the most important driver of clear cell renal cell carcinoma (ccRCC). Although considered undruggable,…”
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Diagnostic Utility of a Likert Scale Versus Qualitative Descriptors and Length of Capsular Contact for Determining Extraprostatic Tumor Extension at Multiparametric Prostate MRI
Published in American journal of roentgenology (1976) (01-05-2018)“…The purpose of this study is to determine the reproducibility and diagnostic performance of a Likert scale in comparison with the European Society of…”
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Prospective Inclusion of Apparent Diffusion Coefficients in Multiparametric Prostate MRI Structured Reports: Discrimination of Clinically Insignificant and Significant Cancers
Published in American journal of roentgenology (1976) (01-01-2019)“…The purpose of this study was to assess the diagnostic performance of prospectively assigned mean apparent diffusion coefficient (ADC) values in…”
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Case 258: Granulomatous Prostatitis
Published in Radiology (01-10-2018)“…History A 68-year-old man with a remote history of a previously resected high-grade urothelial carcinoma in the renal pelvis was being observed and was…”
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Role of Virtual Biopsy in the Management of Renal Masses
Published in American journal of roentgenology (1976) (01-06-2019)“…Renal masses comprise a heterogeneous group of pathologic conditions, including benign and indolent diseases and aggressive malignancies, complicating…”
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Current Challenges in Diagnosis and Assessment of the Response of Locally Advanced and Metastatic Renal Cell Carcinoma
Published in Radiographics (01-07-2019)“…Locally advanced and metastatic renal cell carcinoma (RCC) present a specific set of challenges to the radiologist. The detection of metastatic disease is…”
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Outcome and Immune Correlates of a Phase II Trial of High-Dose Interleukin-2 and Stereotactic Ablative Radiotherapy for Metastatic Renal Cell Carcinoma
Published in Clinical cancer research (15-12-2021)“…This phase II clinical trial evaluated whether the addition of stereotactic ablative radiotherapy (SAbR), which may promote tumor antigen presentation,…”
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Prevalence and clinical significance of discordant LI-RADS® observations on multiphase contrast-enhanced MRI in patients with cirrhosis
Published in Abdominal radiology (New York) (2020)“…Purpose To determine the prevalence and clinical significance of discordant LI-RADS ® (Liver Imaging Reporting and Data System) liver observations on…”
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