Search Results - "Leohr, Jennifer K"
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Analysis of sphingolipids in extracted human plasma using liquid chromatography electrospray ionization tandem mass spectrometry
Published in Analytical biochemistry (15-04-2012)“…We have developed an analytical method used to quantify sphingolipids, including deoxysphingoid bases, in lipid extracts prepared from human plasma. In total,…”
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Evaluation of the Pharmacokinetic Profile of Ultra Rapid Lispro Administered Subcutaneously at Different Injection Sites
Published in Clinical therapeutics (01-06-2022)“…Ultra rapid lispro (URLi) is a novel insulin lispro formulation developed to more closely match physiological insulin secretion and improve postprandial…”
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Serum Lipid and Protein Changes in Healthy Dyslipidemic Subjects Given a Selective Inhibitor of p70 S6 Kinase‐1
Published in Journal of clinical pharmacology (01-04-2018)“…The safety, pharmacokinetic, and pharmacodynamic effects of LY2584702, a selective inhibitor for p70 S6 serine/threonine protein kinase‐1, were evaluated in…”
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Identification of 4-Aminopyrazolopyrimidine Metabolite That May Contribute to the Hypolipidemic Effects of LY2584702 in Long Evans Diet-Induced Obese Rats
Published in The Journal of pharmacology and experimental therapeutics (01-07-2017)“…LY2584702 is an inhibitor of p70 S6 kinase-1 previously developed for the treatment of cancer. In two phase 1 trials in oncology patients, significant…”
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Abstract A86: A phase 1 study of LY2523355, an Eg5 inhibitor, administered on Days 1, 2, and 3 with or without pegfilgrastim in patients with advanced malignancy (NCT01214629)
Published in Molecular cancer therapeutics (12-11-2011)“…Abstract Background: LY2523355 is a potent allosteric inhibitor of the motor protein Eg5 which selectively inhibits bipolar mitotic spindle formation. The…”
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Expression of a Mutated Form of Hepatic Nuclear Factor-4[Alpha]1 Attenuates Glucose-Stimulated Insulin Secretion in [Beta]TC6, F7 Cells
Published in Diabetes (New York, N.Y.) (01-05-1999)Get full text
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