Search Results - "León, Iker"

Revisiting the Spectroscopy of Water Dimer in Jets by León, Iker, Montero, Raúl, Longarte, Asier, Fernández, José A.

“…Laser spectroscopy in jets is one of the main sources of structural data from molecular aggregates. Consequently, numerous and sophisticated experimental…”
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The Nicotinic Agonist Cytisine: The Role of the NH···N Interaction by Aguado, Raúl, Mata, Santiago, Sanz-Novo, Miguel, Alonso, Elena R., León, Iker, Alonso, José L.

“…We report a detailed structural study of cytisine, an alkaloid used to help with smoking cessation, looking forward to unveiling its role as a nicotinic…”
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Synthesis and Spectroscopic Characterization of Interstellar Candidate Ethynyl Thiocyanate: HCCSCN by Alonso, Elena R., Insausti, Aran, Kolesniková, Lucie, León, Iker, McGuire, Brett A., Shingledecker, Christopher N., Agúndez, Marcelino, Cernicharo, José, Rivilla, Víctor M., Cabezas, Carlos, Jiménez-Serra, Izaskun, Martín-Pintado, Jesús, Guillemin, Jean-Claude

“…This work aims to spectroscopically characterize and provide for the first time direct experimental frequencies of the ground vibrational state and two excited…”
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Modeling the tyrosine-sugar interactions in supersonic expansions: glucopyranose-phenol clusters by Usabiaga, Imanol, González, Jorge, Arnáiz, Pedro F, León, Iker, Cocinero, Emilio J, Fernández, José A

“…Sugars are fundamental building blocks for living organisms and their interaction with proteins plays a central role in fundamental biological processes, such…”
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Transition from Planar to Nonplanar Hydrogen Bond Networks in the Solvation of Aromatic Dimers: Propofol2‑(H2O)2–4 by León, Iker, Millán, Judith, Cocinero, Emilio J, Lesarri, Alberto, Fernández, José A

“…Propofol (2,6-diisopropylphenol) is probably the most widely used intravenous general anesthetic. In this work, the interaction of propofol dimer with 2–4…”
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Formation of water polyhedrons in propofol-water clusters by León, Iker, Cocinero, Emilio J, Rijs, Anouk M, Millán, Judith, Alonso, Eduardo, Lesarri, Alberto, Fernández, José A

“…Following previous structural investigations on the hydrated clusters of the anesthetic propofol we analyze here the spectroscopy of propofol·(H(2)O)(7-9) in…”
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A Spectroscopic Approach to the Solvation of Anesthetics in Jets: Propofol(H2O) n , n = 4–6 by León, Iker, Cocinero, Emilio J, Lesarri, Alberto, Castaño, Fernando, Fernández, José A

“…Propofol is a widely used nonvolatile anesthetic that exerts its action by docking to GABAA receptors. The docking process is a competition between solvation…”
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Revealing the Structure of 6‑Aminopenillanic Acid: The Active Nucleus of Penicillins by Mato, Sergio, Mata, Santiago, Alonso, Elena R., León, Iker

“…6-Aminopenicillanic acid is a penicillanic acid compound and is the active nucleus common to all penicillins. Using laser ablation techniques, we transformed…”
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Shape of Testosterone by León, Iker, Alonso, Elena R, Mata, Santiago, Alonso, José L

“…We have successfully characterized the structure of testosterone, one of the essential steroids, through high-resolution rotational spectroscopy. A single…”
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Exploring the Maze of Cycloserine Conformers in the Gas Phase Guided by Microwave Spectroscopy and Quantum Chemistry by Alonso, Elena R, Fusè, Marco, León, Iker, Puzzarini, Cristina, Alonso, José L, Barone, Vincenzo

“…Cycloserine has in common with isoxazolidines the saturated five-membered ring, which is an important scaffold for drug design, exhibiting diverse biological…”
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Revealing the Structure of Sheer N‑Acetylglucosamine, an Essential Chemical Scaffold in Glycobiology by Alonso, Elena R., Insausti, Aran, Peña, Isabel, Sanz-Novo, Miguel, Aguado, Raúl, León, Iker, Alonso, José L.

“…We explored the conformational landscape of N-acetyl-α-d-glucosamine (α-GlcNAc), a fundamental chemical scaffold in glycobiology. Solid samples were vaporized…”
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Unveiling Five Naked Structures of Tartaric Acid by Alonso, Elena R., León, Iker, Kolesniková, Lucie, Mata, Santiago, Alonso, Jose Luis

“…The unbiased, naked structures of tartaric acid, one of the most important organic compounds existing in nature and a candidate to be present in the…”
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Unveiling the Neutral Forms of Glutamine by León, Iker, Alonso, Elena R., Mata, Santiago, Cabezas, Carlos, Alonso, Jose Luis

“…Neutral glutamine has been evaporated by laser ablation of its solid sample to seed a rare gas carrier prior to a supersonic expansion and proved by Fourier…”
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Laser Ablation Assists Cyclization Reactions of Hydantoic Acid: A Proof for the Near-Attack Conformation Theory? by Kolesniková, Lucie, León, Iker, Alonso, Elena R, Mata, Santiago, Alonso, Jose L

“…In the course of the investigation of the rotational spectrum of prebiotic hydantoic acid by Fourier transform microwave spectroscopy coupled to a laser…”
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Computational study on the affinity of potential drugs to SARS-CoV-2 main protease by Martín, Verónica, Sanz-Novo, Miguel, León, Iker, Redondo, Pilar, Largo, Antonio, Barrientos, Carmen

“…Herein, we report a computational investigation of the binding affinity of dexamethasone, betamethasone, chloroquine and hydroxychloroquine to SARS-CoV-2 main…”
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An Innovative Approach for the Generation of Species of the Interstellar Medium by Kolesniková, Lucie, León, Iker, Alonso, Elena R., Mata, Santiago, Alonso, Jose Luis

“…The large amount of unstable species in the realm of interstellar chemistry drives an urgent need to develop efficient methods for the in situ generations of…”
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Rotational Spectrum of Saccharin: Structure and Sweetness by Alonso, Elena R, León, Iker, Kolesniková, Lucie, Alonso, Jose L

“…We present the first high-resolution rotational study of the artificial sweetener saccharin. By combining laser ablation (LA), narrow- and broadband Fourier…”
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Rotational Spectroscopy as a Tool to Characterize Sweet Taste: The Study of Dulcin by Juarez, Gabriela, Alonso, Elena R., Aguado, Raúl, León, Iker

“…According to old theories of sweetness, the perception of sweet substances is closely linked to the arrangement of atoms within them. To assess the validity of…”
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Rotational Spectrum and Conformational Analysis of Perillartine: Insights into the Structure-Sweetness Relationship by Juárez, Gabriela, Sanz-Novo, Miguel, Alonso, José L, Alonso, Elena R, León, Iker

“…We used high-resolution rotational spectroscopy coupled to a laser ablation source to study the conformational panorama of perillartine, a solid synthetic…”
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The Six Isomers of the Cyclohexanol Dimer: A Delicate Test for Dispersion Models by Juanes, Marcos, Usabiaga, Imanol, León, Iker, Evangelisti, Luca, Fernández, José A., Lesarri, Alberto

“…The cyclohexanol homodimer acts as a delicate test model of the role of dispersion forces in intermolecular association. Whereas phenol produces a single…”
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