Search Results - "Leo, L."
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Neutralizing antibodies against the SARS-CoV-2 Omicron variant BA.1 following homologous and heterologous CoronaVac or BNT162b2 vaccination
Published in Nature medicine (01-03-2022)“…The Omicron variant is rapidly becoming the dominant SARS-CoV-2 virus circulating globally. It is important to define reductions in virus neutralizing activity…”
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Emergence of a novel human coronavirus threatening human health
Published in Nature medicine (01-03-2020)“…In late December 2019, a cluster of patients with ‘atypical pneumonia’ of unknown etiology was reported in Wuhan, China. A novel human coronavirus, now…”
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Viral load of SARS-CoV-2 in clinical samples
Published in The Lancet infectious diseases (01-04-2020)Get full text
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High‐resolution magic angle spinning NMR for intact biological specimen analysis: Initial discovery, recent developments, and future directions
Published in NMR in biomedicine (01-04-2023)“…High‐resolution magic angle spinning (HRMAS) NMR, an approach for intact biological material analysis discovered more than 25 years ago, has been advanced by…”
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Transport Monte Carlo: High-Accuracy Posterior Approximation via Random Transport
Published in Journal of the American Statistical Association (03-07-2023)“…In Bayesian applications, there is a huge interest in rapid and accurate estimation of the posterior distribution, particularly for high dimensional or…”
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Neutralizing antibody titres in SARS-CoV-2 infections
Published in Nature communications (04-01-2021)“…The SARS-CoV-2 pandemic poses the greatest global public health challenge in a century. Neutralizing antibody is a correlate of protection and data on kinetics…”
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Molecular Diagnosis of a Novel Coronavirus (2019-nCoV) Causing an Outbreak of Pneumonia
Published in Clinical chemistry (Baltimore, Md.) (01-04-2020)“…Abstract Background A novel coronavirus of zoonotic origin (2019-nCoV) has recently been identified in patients with acute respiratory disease. This virus is…”
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ORF8 and ORF3b antibodies are accurate serological markers of early and late SARS-CoV-2 infection
Published in Nature immunology (01-10-2020)“…The SARS-CoV-2 virus emerged in December 2019 and has caused a worldwide pandemic due to the lack of any pre-existing immunity. Accurate serology testing is…”
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SARS-CoV-2 Omicron variant replication in human bronchus and lung ex vivo
Published in Nature (London) (24-03-2022)“…The emergence of SARS-CoV-2 variants of concern with progressively increased transmissibility between humans is a threat to global public health. The Omicron…”
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Pathogenesis and transmission of SARS-CoV-2 in golden hamsters
Published in Nature (London) (30-07-2020)“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a novel coronavirus with high nucleotide identity to SARS-CoV and to SARS-related coronaviruses…”
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Cupric Oxide Coating That Rapidly Reduces Infection by SARS-CoV‑2 via Solids
Published in ACS applied materials & interfaces (10-02-2021)“…The ongoing COVID-19 pandemic has created a need for coatings that reduce infection from SARS-CoV-2 via surfaces. Such a coating could be used on common touch…”
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Highly Conserved Protective Epitopes on Influenza B Viruses
Published in Science (American Association for the Advancement of Science) (14-09-2012)“…Identification of broadly neutralizing antibodies against influenza A viruses has raised hopes for the development of monoclonal antibody—based immunotherapy…”
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Immunogenicity of a Third Dose of BNT162b2 to Ancestral Severe Acute Respiratory Syndrome Coronavirus 2 and the Omicron Variant in Adults Who Received 2 Doses of Inactivated Vaccine
Published in Clinical infectious diseases (08-02-2023)“…Limited data exist on antibody responses to mixed vaccination strategies that involve inactivated coronavirus disease 2019 (COVID-19) vaccines, particularly in…”
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A Highly Conserved Neutralizing Epitope on Group 2 Influenza A Viruses
Published in Science (American Association for the Advancement of Science) (12-08-2011)“…Current flu vaccines provide only limited coverage against seasonal strains of influenza viruses. The identification of V H 1-69 antibodies that broadly…”
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Spectral Clustering, Bayesian Spanning Forest, and Forest Process
Published in Journal of the American Statistical Association (02-07-2024)“…Spectral clustering views the similarity matrix as a weighted graph, and partitions the data by minimizing a graph-cut loss. Since it minimizes the…”
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Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin
Published in Science (American Association for the Advancement of Science) (02-11-2018)“…Broadly neutralizing antibodies against highly variable pathogens have stimulated the design of vaccines and therapeutics. We report the use of diverse camelid…”
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Evidence for an Ancestral Association of Human Coronavirus 229E with Bats
Published in Journal of virology (01-12-2015)“…We previously showed that close relatives of human coronavirus 229E (HCoV-229E) exist in African bats. The small sample and limited genomic characterizations…”
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Viral dynamics in mild and severe cases of COVID-19
Published in The Lancet infectious diseases (01-06-2020)“…Patients who had any of the following features at the time of, or after, admission were classified as severe cases: (1) respiratory distress (≥30 breaths per…”
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The first 2019 novel coronavirus case in Nepal
Published in The Lancet infectious diseases (01-03-2020)“…In January, 2020, the outbreak of the 2019 novel coronavirus (2019-nCoV) in China spread progressively to other countries,1,2 with WHO declaring it a Public…”
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Three‐dimensional extrusion bioprinting of single‐ and double‐network hydrogels containing dynamic covalent crosslinks
Published in Journal of biomedical materials research. Part A (01-04-2018)“…The fabrication of three‐dimensional (3D) scaffolds is indispensable to tissue engineering and 3D printing is emerging as an important approach towards this…”
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