Search Results - "Leo, Isabelle Rose"
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Integrative multi-omics and drug response profiling of childhood acute lymphoblastic leukemia cell lines
Published in Nature communications (30-03-2022)“…Acute lymphoblastic leukemia (ALL) is the most common childhood cancer. Although standard-of-care chemotherapeutics are sufficient for most ALL cases, there…”
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Targeting autophagy as a therapeutic strategy in pediatric acute lymphoblastic leukemia
Published in Scientific reports (18-02-2024)“…Autophagy is activated in response to a variety of stress conditions including anti-cancer therapies, and tumors cells often depend on autophagy for survival…”
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Molecular Profiling Defines Three Subtypes of Synovial Sarcoma
Published in Advanced science (01-11-2024)“…Synovial Sarcomas (SS) are characterized by the presence of the SS18::SSX fusion gene, which protein product induce chromatin changes through remodeling of the…”
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Deep thermal profiling for detection of functional proteoform groups
Published in Nature chemical biology (01-08-2023)“…The complexity of the functional proteome extends considerably beyond the coding genome, resulting in millions of proteoforms. Investigation of proteoforms and…”
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Journal Article