Search Results - "Leo, Giacomo De"

Exosomes as intercellular signaling organelles involved in health and disease: basic science and clinical applications by Corrado, Chiara, Raimondo, Stefania, Chiesi, Antonio, Ciccia, Francesco, De Leo, Giacomo, Alessandro, Riccardo

“…Cell to cell communication is essential for the coordination and proper organization of different cell types in multicellular systems. Cells exchange…”
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Interleukin 3- receptor targeted exosomes inhibit in vitro and in vivo Chronic Myelogenous Leukemia cell growth by Bellavia, Daniele, Raimondo, Stefania, Calabrese, Giovanna, Forte, Stefano, Cristaldi, Marta, Patinella, Agostina, Memeo, Lorenzo, Manno, Mauro, Raccosta, Samuele, Diana, Patrizia, Cirrincione, Girolamo, Giavaresi, Gianluca, Monteleone, Francesca, Fontana, Simona, De Leo, Giacomo, Alessandro, Riccardo

“…Despite Imatinib (IM), a selective inhibitor of Bcr-Abl, having led to improved prognosis in Chronic Myeloid Leukemia (CML) patients, acquired resistance and…”
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Identification of biomarkers in cerebrospinal fluid and serum of multiple sclerosis patients by immunoproteomics approach by Colomba, Paolo, Fontana, Simona, Salemi, Giuseppe, Barranca, Marilisa, Lo Sicco, Claudia, Mazzola, Maria Antonietta, Ragonese, Paolo, Savettieri, Giovanni, De Leo, Giacomo, Alessandro, Riccardo, Duro, Giovanni

“…Multiple sclerosis (MS) is an autoimmune inflammatory demyelinating disease of the central nervous system. At present, the molecular mechanisms causing the…”
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CD90+ liver cancer cells modulate endothelial cell phenotype through the release of exosomes containing H19 lncRNA by Conigliaro, Alice, Costa, Viviana, Lo Dico, Alessia, Saieva, Laura, Buccheri, Simona, Dieli, Francesco, Manno, Mauro, Raccosta, Samuele, Mancone, Carmine, Tripodi, Marco, De Leo, Giacomo, Alessandro, Riccardo

“…CD90+ liver cancer cells have been described as cancer stem-cell-like (CSC), displaying aggressive and metastatic phenotype. Using two different in vitro…”
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Role of exosomes released by chronic myelogenous leukemia cells in angiogenesis by Taverna, Simona, Flugy, Anna, Saieva, Laura, Kohn, Elise C, Santoro, Alessandra, Meraviglia, Serena, De Leo, Giacomo, Alessandro, Riccardo

“…Our study is designed to assess if exosomes released from chronic myelogenous leukemia (CML) cells may modulate angiogenesis. We have isolated and…”
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Exosomal shuttling of miR-126 in endothelial cells modulates adhesive and migratory abilities of chronic myelogenous leukemia cells by Taverna, Simona, Amodeo, Valeria, Saieva, Laura, Russo, Antonio, Giallombardo, Marco, De Leo, Giacomo, Alessandro, Riccardo

“…Recent findings indicate that exosomes released from cancer cells contain microRNAs (miRNAs) that may be delivered to cells of tumor microenvironment. To…”
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Exosomes released by K562 chronic myeloid leukemia cells promote angiogenesis in a src-dependent fashion by Mineo, Marco, Garfield, Susan H., Taverna, Simona, Flugy, Anna, De Leo, Giacomo, Alessandro, Riccardo, Kohn, Elise C.

“…Exosomes, microvesicles of endocytic origin released by normal and tumor cells, play an important role in cell-to-cell communication. Angiogenesis has been…”
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Curcumin modulates chronic myelogenous leukemia exosomes composition and affects angiogenic phenotype via exosomal miR-21 by Taverna, Simona, Fontana, Simona, Monteleone, Francesca, Pucci, Marzia, Saieva, Laura, De Caro, Viviana, Cardinale, Valeria Giunta, Giallombardo, Marco, Vicario, Emanuela, Rolfo, Christian, Leo, Giacomo De, Alessandro, Riccardo

“…Tumor derived exosomes are vesicles which contain proteins and microRNAs that mediate cell-cell communication and are involved in angiogenesis and tumor…”
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Carboxyamidotriazole-orotate inhibits the growth of imatinib-resistant chronic myeloid leukaemia cells and modulates exosomes-stimulated angiogenesis by Corrado, Chiara, Flugy, Anna Maria, Taverna, Simona, Raimondo, Stefania, Guggino, Giuliana, Karmali, Rashida, De Leo, Giacomo, Alessandro, Riccardo

“…The Bcr/Abl kinase has been targeted for the treatment of chronic myelogenous leukaemia (CML) by imatinib mesylate. While imatinib has been extremely effective…”
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Role of Extracellular Vesicles in Hematological Malignancies by De Leo, Giacomo, Raimondi, Lavinia, Corrado, Chiara, Raimondo, Stefania, Alessandro, Riccardo

“…In recent years the role of tumor microenvironment in the progression of hematological malignancies has been widely recognized. Recent studies have focused on…”
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Preliminary Results of CitraVes™ Effects on Low Density Lipoprotein Cholesterol and Waist Circumference in Healthy Subjects after 12 Weeks: A Pilot Open-Label Study by Raimondo, Stefania, Nikolic, Dragana, Conigliaro, Alice, Giavaresi, Gianluca, Lo Sasso, Bruna, Giglio, Rosaria Vincenza, Chianetta, Roberta, Manno, Mauro, Raccosta, Samuele, Corleone, Valeria, Ferrante, Giovanni, Citarrella, Roberto, Rizzo, Manfredi, De Leo, Giacomo, Ciaccio, Marcello, Montalto, Giuseppe, Alessandro, Riccardo

“…Appropriate monitoring and control of modifiable risk factors, such as the level of low-density lipoprotein cholesterol (LDL-C) and other types of…”
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Involvement of multiple myeloma cell-derived exosomes in osteoclast differentiation by Raimondi, Lavinia, De Luca, Angela, Amodio, Nicola, Manno, Mauro, Raccosta, Samuele, Taverna, Simona, Bellavia, Daniele, Naselli, Flores, Fontana, Simona, Schillaci, Odessa, Giardino, Roberto, Fini, Milena, Tassone, Pierfrancesco, Santoro, Alessandra, De Leo, Giacomo, Giavaresi, Gianluca, Alessandro, Riccardo

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Increased expression of interleukin-32 in the inflamed ileum of ankylosing spondylitis patients by CICCIA, Francesco, RIZZO, Aroldo, ACCARDO-PALUMBO, Antonina, GIARDINA, Annarita, BOMBARDIERI, Michele, GUGGINO, Giuliana, TAVERNA, Simona, DE LEO, Giacomo, ALESSANDRO, Riccardo, TRIOLO, Giovanni

“…To study the mRNA expression and protein tissue distribution of IL-32 in ileal biopsy specimens from patients with AS. Quantitative gene expression analysis,…”
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Carboxyamidotriazole inhibits cell growth of imatinib-resistant chronic myeloid leukaemia cells including T315I Bcr–Abl mutant by a redox-mediated mechanism by Corrado, Chiara, Raimondo, Stefania, Flugy, Anna Maria, Fontana, Simona, Santoro, Alessandra, Stassi, Giorgio, Marfia, Anna, Iovino, Flora, Arlinghaus, Ralph, Kohn, Elise C, Leo, Giacomo De, Alessandro, Riccardo

“…Abstract Mutation of the Bcr–Abl oncoprotein is one of most frequent mechanisms by which chronic myelogenous leukemia (CML) cells become resistant to imatinib…”
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Role of S128R polymorphism of E‐selectin in colon metastasis formation by Alessandro, Riccardo, Seidita, Gregorio, Flugy, Anna Maria, Damiani, Francesca, Russo, Antonio, Corrado, Chiara, Colomba, Paolo, Gullotti, Lucia, Buettner, Reinhard, Bruno, Loredana, Leo, Giacomo De

“…The extravasation of cancer cells is a key step of the metastatic cascade. Polymorphisms in genes encoding adhesion molecules can facilitate metastasis by…”
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Ras-pathway has a dual role in yeast galactose metabolism by Mirisola, Mario G., Gallo, Alessia, Leo, Giacomo De

“…In the yeast Saccharomyces cerevisiae the genes involved in galactose metabolism (GAL1,7,10) are transcriptionally activated more than a 1000-fold in the…”
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Yeast vectors for the integration/expression of any sequence at the TYR1 locus by Mirisola, Mario G, Colomba, Leonarda, Gallo, Alessia, Amodeo, Roberta, De Leo, Giacomo

“…We have constructed new yeast vectors for targeted integration and conditional expression of any sequence at the Saccharomyces cerevisiae TYR1 locus which…”
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Type 3 innate lymphoid cells producing IL-17 and IL-22 are expanded in the gut, in the peripheral blood, synovial fluid and bone marrow of patients with ankylosing spondylitis by Ciccia, Francesco, Guggino, Giuliana, Rizzo, Aroldo, Saieva, Laura, Peralta, Sergio, Giardina, AnnaRita, Cannizzaro, Alessandra, Sireci, Guido, De Leo, Giacomo, Alessandro, Riccardo, Triolo, Giovanni

“…The aim of the study was to better characterise the immunological origin and the behaviour of interleukin (IL)-23-responsive innate lymphoid cells (ILCs) in…”
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Citrus limon-derived nanovesicles inhibit cancer cell proliferation and suppress CML xenograft growth by inducing TRAIL-mediated cell death by Raimondo, Stefania, Naselli, Flores, Fontana, Simona, Monteleone, Francesca, Lo Dico, Alessia, Saieva, Laura, Zito, Giovanni, Flugy, Anna, Manno, Mauro, Di Bella, Maria Antonietta, De Leo, Giacomo, Alessandro, Riccardo

“…Nanosized vesicles are considered key players in cell to cell communication, thus influencing physiological and pathological processes, including cancer…”
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Chronic myelogenous leukaemia exosomes modulate bone marrow microenvironment through activation of epidermal growth factor receptor by Corrado, Chiara, Saieva, Laura, Raimondo, Stefania, Santoro, Alessandra, De Leo, Giacomo, Alessandro, Riccardo

“…Chronic myelogenous leukaemia (CML) is a clonal myeloproliferative disorder. Recent evidence indicates that altered crosstalk between CML and mesenchymal…”
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