Search Results - "Lenz, George"

Medicinal Chemical Properties of Successful Central Nervous System Drugs by Pajouhesh, Hassan, Lenz, George R.

“…Fundamental physiochemical features of CNS drugs are related to their ability to penetrate the blood-brain barrier affinity and exhibit CNS activity. Factors…”
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Chemical ligands, genomics and drug discovery by Lenz, George R, Nash, Huw M, Jindal, Satish

“…The sequencing of the human genome and numerous pathogen genomes has resulted in an explosion of potential drug targets. These targets represent both an…”
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Oxidative Rearrangement of 1-Alkylidene-1,2,3,4-tetrahydro-2-(trichloroacetyl)isoquinolines to 1,5,6,10b-Tetrahydro-10b-(trichloromethyl)-3H-oxazolo[4,3-a]isoquinolin-3-ones by Lenz, George R., Lessor, Ralph A., Rafalko, Patrice W., Ezell, Edward F., Kosarych, Zenyk, Meyer, Lars, Margaretha, Paul

“…On treatment with lead tetraacetate (Pb(OAc)4), the 1‐(alkylidene)‐1,2,3,4‐tetrahydro‐N‐(trichloroacetyl)isoquinolines 2a–2c as well as the tribromoacetyl…”
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Lead tetraacetate mediated oxidation of the enamides derived from 1-benzyl-3,4-dihydroisoquinolines by Lenz, George R, Costanza, Carl

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Synthesis of 7-oxygenated aporphine alkaloids from a 1-benzylideneisoquinoline enamide by Lenz, George R

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Oxidative ring expansion of isoquinoline enamides. Facile formation of 3-benzazepines by Lenz, George R

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Mantle cell lymphoma: established therapeutic options and future directions by Lenz, G, Dreyling, M, Hiddemann, W

“…During the last few years, new insights into the biology of mantle cell lymphoma have been obtained. However, with a median survival of only 3 years, mantle…”
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Enamide photochemistry. Stereochemistry of photocyclization of 1-ethylidene and 1-benzylidene 2-benzoyltetrahydroisoquinolines by Lenz, George R

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Steroid photochemistry. Photocycloaddition of cyclopropylenones to dienes. An example of a [.pi.2 + .pi.2 + .pi.2 + .sigma.2] addition by Lenz, George R

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Enamide photochemistry. Formation of oxyprotoberberines by the elimination of ortho substituents in 2-aroyl-1-methylene-1,2,3,4-tetrahydroisoquinolines by Lenz, George R

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Enamide photochemistry. Formation of 8-oxoberbines from 2-aroyl-1-methylene-1,2,3,4-tetrahydroisoquinolines by Lenz, George R

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Oxidative cyclization of acyclic aryl-substituted N-vinylurethanes by Lenz, George R, Costanza, Carl, Lessor, Ralph A, Ezell, Edward F

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The synthesis of the isoquinoline alkaloid calycotomine via functionalization of enamide double bonds by LENZ, G. R

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The Synthesis of Oxoaporphines and Phenanthrenediones from 7-Hydroxydehydronoraporphines by R. Lenz, George, Costanza, Carl, A. Lessor, Ralph

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Lead tetraacetate oxidation of oxyprotoberberines. A convenient synthesis of 13-oxygenated berbines and oxyprotoberberines by Koszyk, Francis J, Lenz, George R

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Steroid photochemistry. Photocycloaddition of a linear dienone to Diels-Alder 1,3-dienes by Lenz, George R

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Steroid photochemistry. Facile [4 + 2] adduct formation in the photocycloaddition of an enedione to olefins and dienes by Lenz, George R

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Reaction of isoquinoline enamides with electrophiles by Lenz, George R, Woo, Chi Min, Hawkins, Bruce L

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Enamide photochemistry. Synthesis of protoberberine iodides from 1-benzylidene-3,4-dihydro-2(1H)-isoquinoline carboxaldehydes by Lenz, George R

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Synthesis of the 13,17 side chain switched isomers of 18-hydroxy- and 18-oxoprogesterone and -deoxycorticosterone by Lenz, George R, Dorn, Clifford R

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