Search Results - "Lentz, S."

Alkaline intracellular pH (pHi) activates AMPK–mTORC2 signaling to promote cell survival during growth factor limitation by Kazyken, D., Lentz, S.I., Fingar, D.C.

“…The mechanistic target of rapamycin (mTOR) complex 2 (mTORC2) signaling controls cell metabolism, promotes cell survival, and contributes to tumorigenesis, yet…”
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Seasonal warming of the Middle Atlantic Bight Cold Pool by Lentz, S. J.

“…The Cold Pool is a 20–60 m thick band of cold, near‐bottom water that persists from spring to fall over the midshelf and outer shelf of the Middle Atlantic…”
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Enhancing the pharmacokinetic properties of recombinant factor VIII: first‐in‐human trial of glycoPEGylated recombinant factor VIII in patients with hemophilia A by Tiede, A., Brand, B., Fischer, R., Kavakli, K., Lentz, S. R., Matsushita, T., Rea, C., Knobe, K., Viuff, D.

“…Summary Background N8‐GP is a recombinant factor VIII (FVIII) with a site‐directed glycoPEGylation for the purpose of half‐life prolongation. Objectives To…”
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Genetic testing to guide warfarin dosing: Impact of direct oral anticoagulants by Lentz, SR

“…Despite rapid growth in the use of direct oral anticoagulants (DOACs), warfarin remains a widely prescribed anticoagulant drug. It is likely that the overall…”
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Diabetes regulates mitochondrial biogenesis and fission in mouse neurons by Edwards, J. L, Quattrini, A, Lentz, S. I, Figueroa-Romero, C, Cerri, F, Backus, C, Hong, Y, Feldman, E. L

“…Aims/hypothesis Normal mitochondrial activity is a critical component of neuronal metabolism and function. Disruption of mitochondrial activity by altered…”
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Mechanisms of homocysteine‐induced atherothrombosis by LENTZ, S. R.

“…Elevation of plasma homocysteine level is a risk factor for cardiovascular disease, stroke, and venous thromboembolism. It is still uncertain, however, whether…”
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Lymphatic Mapping and Sentinel Lymph Node Biopsy in Women With Squamous Cell Carcinoma of the Vulva: A Gynecologic Oncology Group Study by LEVENBACK, Charles F, ALI, Shamshad, LEITAO, Mario M, BAKKUM-GAMEZ, Jamie N, ROSSI, Emma C, LENTZ, Samuel S, BURKE, James J, VAN LE, Linda, TRIMBLE, Cornelia L, COLEMAN, Robert L, GOLD, Michael A, FOWLER, Jeffrey M, JUDSON, Patricia L, BELL, Maria C, DE GEEST, Koen, SPIRTOS, Nick M, POTKUL, Ronald K

“…To determine the safety of sentinel lymph node biopsy as a replacement for inguinal femoral lymphadenectomy in selected women with vulvar cancer. Eligible…”
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ADAMTS13 reduces VWF‐mediated acute inflammation following focal cerebral ischemia in mice by KHAN, M. M., MOTTO, D. G., LENTZ, S. R., CHAUHAN, A. K.

“…Background:  ADAMTS13 cleaves hyperactive ultra‐large von Willebrand factor (ULVWF) multimers into smaller and less active forms. It remains unknown whether…”
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Human chorionic gonadotropin promotes murine Treg cells and restricts pregnancy-harmful proinflammatory Th17 responses by Lentz, Lea S., Stutz, Annika J., Meyer, Nicole, Schubert, Kristin, Karkossa, Isabel, von Bergen, Martin, Zenclussen, Ana C., Schumacher, Anne

“…An equilibrium between proinflammatory and anti-inflammatory immune responses is essential for maternal tolerance of the fetus throughout gestation. To study…”
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From Differential Stains to Next Generation Physiology: Chemical Probes to Visualize Bacterial Cell Structure and Physiology by Hira, Jonathan, Uddin, Md Jalal, Haugland, Marius M, Lentz, Christian S

“…Chemical probes have been instrumental in microbiology since its birth as a discipline in the 19th century when chemical dyes were used to visualize structural…”
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Development of an inducer-free, virulence gene promoter-controlled, and fluorescent reporter-labeled CRISPR interference system in Staphylococcus aureus by Miah, Roni, Johannessen, Mona, Kjos, Morten, Lentz, Christian S

“…The dCas9-based Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) interference (CRISPRi) gene regulation technique requires two components: a…”
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Magnetization transfer ratio: a quantitative imaging biomarker for 5q spinal muscular atrophy by Kollmer, J., Kessler, T., Sam, G., Hayes, J. M., Lentz, S. I., Heiland, S., Bendszus, M., Wick, W., Weiler, M.

“…In this exploratory study, we used magnetization transfer contrast (MTC) imaging, an MRI technique that provides information about protons bound to…”
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Role of hyperhomocysteinemia in endothelial dysfunction and atherothrombotic disease by Austin, R C, Lentz, S R, Werstuck, G H

“…Hyperhomocysteinemia (HHcy) is an independent risk factor for cardiovascular disease, including ischemic heart disease, stroke, and peripheral vascular…”
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A phase III randomized trial of postoperative pelvic irradiation in Stage IB cervical carcinoma with poor prognostic features: follow-up of a gynecologic oncology group study by Rotman, Marvin, Sedlis, Alexander, Piedmonte, Marion R, Bundy, Brian, Lentz, Samuel S, Muderspach, Laila I, Zaino, Richard J

“…To investigate, in a phase III randomized trial, whether postoperative external-beam irradiation to the standard pelvic field improves the recurrence-free…”
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Resistance Revisited: Disillusionment, Hierarchies and the Brain by Lentz, Joan, S.

“…With the proliferation of new psychoanalytic theories and methods, some concepts, such as resistance and free association, have been cast aside. This paper…”
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Inhibition of NGLY1 Inactivates the Transcription Factor Nrf1 and Potentiates Proteasome Inhibitor Cytotoxicity by Tomlin, Frederick M, Gerling-Driessen, Ulla I. M, Liu, Yi-Chang, Flynn, Ryan A, Vangala, Janakiram R, Lentz, Christian S, Clauder-Muenster, Sandra, Jakob, Petra, Mueller, William F, Ordoñez-Rueda, Diana, Paulsen, Malte, Matsui, Naoko, Foley, Deirdre, Rafalko, Agnes, Suzuki, Tadashi, Bogyo, Matthew, Steinmetz, Lars M, Radhakrishnan, Senthil K, Bertozzi, Carolyn R

“…Proteasome inhibitors are used to treat blood cancers such as multiple myeloma (MM) and mantle cell lymphoma. The efficacy of these drugs is frequently…”
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Designing of spider silk proteins for human induced pluripotent stem cell-based cardiac tissue engineering by Esser, T.U., Trossmann, V.T., Lentz, S., Engel, F.B., Scheibel, T.

“…Materials made of recombinant spider silk proteins are promising candidates for cardiac tissue engineering, and their suitability has so far been investigated…”
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Assessment of the impact of treatment on quality of life of patients with haemophilia A at different ages: insights from two clinical trials on turoctocog alfa by Santagostino, E., Lentz, S. R., Busk, A. K., Regnault, A., Iorio, A.

“…Summary Haemophilia and its treatment interfere with patients' life, so health‐related quality of life (HRQoL) should be assessed when evaluating treatments…”
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Urinary comprehensive genomic profiling predicts urothelial carcinoma recurrence and identifies responders to intravesical therapy by Rac, Goran, Patel, Hiten D., James, Christopher, Desai, Shalin, Caruso, Vincent M., Fischer, Daniel S., Lentz, Peter S., Ward, Ceressa T., Mazzarella, Brian C., Phillips, Kevin G., Doshi, Chirag, Bicocca, Vincent T., Levin, Trevor G., Wolfe, Alan J., Gupta, Gopal N.

“…Intravesical therapy (IVT) is the standard of care to decrease risk of recurrence and progression for high‐grade nonmuscle‐invasive bladder cancer. However,…”
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Does Pre-Operative Vaginal Metronidazole Decrease the Risk of Pelvic Infections following Robotic Radical Hysterectomy? by Avila, M, Lentz, S, Axtell, A

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