Search Results - "Lentini, M"

TRMT1-Catalyzed tRNA Modifications Are Required for Redox Homeostasis To Ensure Proper Cellular Proliferation and Oxidative Stress Survival by Dewe, Joshua M., Fuller, Benjamin L., Lentini, Jenna M., Kellner, Stefanie M., Fu, Dragony

“…Mutations in the tRNA methyltransferase 1 (TRMT1) gene have been identified as the cause of certain forms of autosomal-recessive intellectual disability (ID)…”
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DALRD3 encodes a protein mutated in epileptic encephalopathy that targets arginine tRNAs for 3-methylcytosine modification by Lentini, Jenna M., Alsaif, Hessa S., Faqeih, Eissa, Alkuraya, Fowzan S., Fu, Dragony

“…In mammals, a subset of arginine tRNA isoacceptors are methylated in the anticodon loop by the METTL2 methyltransferase to form the 3-methylcytosine (m3C)…”
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Evaluation of headstarting as a conservation tool to recover Blanding's Turtles (Emydoidea blandingii) in a highly fragmented urban landscape by Wijewardena, Tharusha, Keevil, Matthew G, Mandrak, Nicholas E, Lentini, Andrew M, Litzgus, Jacqueline D

“…Freshwater turtle populations are declining globally as a result of anthropogenic activities. Threats to turtles in urban areas are exacerbated by road…”
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Effects of heavy metals on ultrastructure and Hsp70 induction in Lemna minor L. exposed to water along the Sarno River, Italy by Basile, A, Sorbo, S, Cardi, M, Lentini, M, Castiglia, D, Cianciullo, P, Conte, B, Loppi, S, Esposito, S

“…The effects of freshwater pollution in the highly contaminated river Sarno (Campania, Southern Italy) have been evaluated using bags containing the aquatic…”
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An intellectual disability‐associated missense variant in TRMT1 impairs tRNA modification and reconstitution of enzymatic activity by Zhang, Kejia, Lentini, Jenna M., Prevost, Christopher T., Hashem, Mais O., Alkuraya, Fowzan S., Fu, Dragony

“…The human TRMT1 gene encodes an RNA methyltransferase enzyme responsible for catalyzing dimethylguanosine (m2,2G) formation in transfer RNAs (tRNAs)…”
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Proteolytic cleavage and inactivation of the TRMT1 tRNA modification enzyme by SARS-CoV-2 main protease by Zhang, Kejia, Eldin, Patrick, Ciesla, Jessica H, Briant, Laurence, Lentini, Jenna M, Ramos, Jillian, Cobb, Justin, Munger, Joshua, Fu, Dragony

“…Nonstructural protein 5 (Nsp5) is the main protease of SARS-CoV-2 that cleaves viral polyproteins into individual polypeptides necessary for viral replication…”
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Hearing Loss and Oxidative Stress: A Comprehensive Review by Maniaci, A, La Via, L, Lechien, J R, Sangiorgio, G, Iannella, G, Magliulo, G, Pace, A, Mat, Q, Lavalle, S, Lentini, M

“…Hearing loss is a prevalent condition affecting millions of people worldwide. Hearing loss has been linked to oxidative stress as a major factor in its onset…”
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Epileptic encephalopathy linked to a DALRD3 missense variant that impairs tRNA modification by Zhang, Kejia, Löhner, Katharina, Lemmink, Henny H., Boon, Maartje, Lentini, Jenna M., de Silva, Naduni, Fu, Dragony

“…Epileptic encephalopathies are severe epilepsy syndromes characterized by early onset and progressive cerebral dysfunction. A nonsense variant in the DALR…”
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Differential expression of transglutaminase genes in patients with chronic periodontitis by Currò, M, Matarese, G, Isola, G, Caccamo, D, Ventura, VP, Cornelius, C, Lentini, M, Cordasco, G, Ientile, R

“…Objective Gingival epithelium plays a key role in the protection of oral tissues from microbial challenge, especially during the periodontal disease. This…”
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Elp3 and RlmN: A tale of two mitochondrial tail-anchored radical SAM enzymes in Toxoplasma gondii by Padgett, Leah R, Lentini, Jenna M, Holmes, Michael J, Stilger, Krista L, Fu, Dragony, Sullivan, Jr, William J

“…Radical S-adenosylmethionine (rSAM) enzymes use a 5'-deoxyadensyl 5'-radical to methylate a wide array of diverse substrates including proteins, lipids and…”
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Predation and disease limit population recovery following 15 years of headstarting an endangered freshwater turtle by Mullin, Damien I., White, Rachel C., Lentini, Andrew M., Brooks, Ronald J., Bériault, Karine R., Litzgus, Jacqueline D.

“…Recovery strategies for endangered species vary in scope and scale, and uncertainties regarding their effectiveness make it necessary to implement…”
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Design of C 2 algebraic-trigonometric pythagorean hodograph splines with shape parameters by González, C, Albrecht, G, Paluszny, M, Lentini, M

“…In this paper, we construct C2 Algebraic-Trigonometric Pythagorean Hodograph (ATPH) splines by solving a non-linear system of equations in complex variables…”
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Road avoidance and its energetic consequences for reptiles by Paterson, James E., Baxter‐Gilbert, James, Beaudry, Frederic, Carstairs, Sue, Chow‐Fraser, Patricia, Edge, Christopher B., Lentini, Andrew M., Litzgus, Jacqueline D., Markle, Chantel E., McKeown, Kassie, Moore, Jennifer A., Refsnider, Jeanine M., Riley, Julia L., Rouse, Jeremy D., Seburn, David C., Zimmerling, J. Ryan, Davy, Christina M.

“…Roads are one of the most widespread human‐caused habitat modifications that can increase wildlife mortality rates and alter behavior. Roads can act as…”
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Climatic and geographic predictors of life history variation in Eastern Massasauga (Sistrurus catenatus): A range-wide synthesis by Hileman, Eric T, King, Richard B, Adamski, John M, Anton, Thomas G, Bailey, Robyn L, Baker, Sarah J, Bieser, Nickolas D, Bell, Jr, Thomas A, Bissell, Kristin M, Bradke, Danielle R, Campa, 3rd, Henry, Casper, Gary S, Cedar, Karen, Cross, Matthew D, DeGregorio, Brett A, Dreslik, Michael J, Faust, Lisa J, Harvey, Daniel S, Hay, Robert W, Jellen, Benjamin C, Johnson, Brent D, Johnson, Glenn, Kiel, Brooke D, Kingsbury, Bruce A, Kowalski, Matthew J, Lee, Yu Man, Lentini, Andrew M, Marshall, John C, Mauger, David, Moore, Jennifer A, Paloski, Rori A, Phillips, Christopher A, Pratt, Paul D, Preney, Thomas, Prior, Kent A, Promaine, Andrew, Redmer, Michael, Reinert, Howard K, Rouse, Jeremy D, Shoemaker, Kevin T, Sutton, Scott, VanDeWalle, Terry J, Weatherhead, Patrick J, Wynn, Doug, Yagi, Anne

“…Elucidating how life history traits vary geographically is important to understanding variation in population dynamics. Because many aspects of ectotherm life…”
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A case of hypertrichotic smooth muscle hamartoma: is it an amelanotic Becker naevus? by Guarneri, C., Lentini, M., Cannavò, S. P., Happle, R.

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Methyltransferase METTL8 is required for 3-methylcytosine modification in human mitochondrial tRNAs by Lentini, Jenna M., Bargabos, Rachel, Chen, Chen, Fu, Dragony

“…A subset of eukaryotic tRNAs is methylated in the anticodon loop, forming 3-methylcytosine (m3C) modifications. In mammals, the number of tRNAs containing m3C…”
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Monitoring the 5-methoxycarbonylmethyl-2-thiouridine (mcm5s2U) modification in eukaryotic tRNAs via the γ-toxin endonuclease by Lentini, Jenna M, Ramos, Jillian, Fu, Dragony

“…The post-transcriptional modification of tRNA at the wobble position is a universal process occurring in all domains of life. In eukaryotes, the wobble uridine…”
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Investigation into FOXE1 genetic variations in cutaneous squamous cell carcinoma by Venza, I., Visalli, M., Tripodo, B., Lentini, M., Teti, D., Venza, M.

“…Summary Background  FOXE1 is a candidate tumour suppressor gene at human chromosome locus 9q22. This is a region frequently lost in squamous cell cancer…”
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tRNA modification enzyme-dependent redox homeostasis regulates synapse formation and memory by Madhwani, Kimberly R., Sayied, Shanzeh, Ogata, Carlson H., Hogan, Caley A., Lentini, Jenna M., Mallik, Moushami, Dumouchel, Jennifer L., Storkebaum, Erik, Fu, Dragony, O’Connor-Giles, Kate M.

“…Post-transcriptional modification of RNA regulates gene expression at multiple levels. ALKBH8 is a tRNA-modifying enzyme that methylates wobble uridines in a…”
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Syndecan-1 and Wingless-type protein-1 in human ameloblastomas by Leocata, P., Villari, D., Fazzari, C., Lentini, M., Fortunato, C., Nicòtina, P. A.

“…Background:  Aberrant Wingless type 1 glycoprotein (Wnt) pathway in ameloblastomas and a role of syndecan‐1 (SDC1) in activating Wnt signalling were…”
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