Search Results - "Lensing, A W"
-
1
Patient-reported treatment satisfaction with oral rivaroxaban versus standard therapy in the treatment of acute symptomatic deep-vein thrombosis
Published in Thrombosis and haemostasis (01-10-2013)“…Rivaroxaban, an oral, direct factor Xa inhibitor, has been approved for the treatment of deep-vein thrombosis (DVT) and pulmonary embolism (PE) and the…”
Get more information
Journal Article -
2
d-Dimer Testing to Determine the Duration of Anticoagulation Therapy
Published in The New England journal of medicine (26-10-2006)“…In a series of patients with venous thromboembolism who had been treated with anticoagulation for at least 3 months, d -dimer testing was performed 1 month…”
Get full text
Journal Article -
3
Pharmacokinetics of rivaroxaban in children using physiologically based and population pharmacokinetic modelling: an EINSTEIN-Jr phase I study
Published in Thrombosis journal (04-12-2018)“…The EINSTEIN-Jr program will evaluate rivaroxaban for the treatment of venous thromboembolism (VTE) in children, targeting exposures similar to the 20 mg…”
Get full text
Journal Article -
4
Long term risk of symptomatic recurrent venous thromboembolism after discontinuation of anticoagulant treatment for first unprovoked venous thromboembolism event: systematic review and meta-analysis
Published in BMJ (Online) (24-07-2019)“…AbstractObjectivesTo determine the rate of a first recurrent venous thromboembolism (VTE) event after discontinuation of anticoagulant treatment in patients…”
Get full text
Journal Article -
5
Exploratory evaluation of pharmacodynamics, pharmacokinetics and safety of rivaroxaban in children and adolescents: an EINSTEIN-Jr phase I study
Published in Thrombosis journal (04-12-2018)“…The EINSTEIN-Jr program will evaluate rivaroxaban for the treatment of venous thromboembolism (VTE) in children, targeting exposures similar to the 20 mg…”
Get full text
Journal Article -
6
Clot resolution after 3 weeks of anticoagulant treatment for pulmonary embolism: comparison of computed tomography and perfusion scintigraphy
Published in Journal of thrombosis and haemostasis (01-04-2013)“…Summary Introduction Little is known about the natural history of clot resolution in the initial weeks of anticoagulant therapy in patients with acute…”
Get full text
Journal Article -
7
Rivaroxaban versus standard anticoagulation for acute venous thromboembolism in childhood. Design of the EINSTEIN-Jr phase III study
Published in Thrombosis journal (21-12-2018)“…Venous thromboembolism (VTE) is a relatively rare condition in childhood with treatment mainly based on extrapolation from studies in adults. Therefore,…”
Get full text
Journal Article -
8
Treatment of venous thromboembolism in patients with cancer: subgroup analysis of the Matisse clinical trials
Published in Thrombosis and haemostasis (01-04-2009)“…In the initial treatment of venous thromboembolism (VTE) fondaparinux, a pentasaccharide, is a good alternative to heparin. Whether this is also true for…”
Get more information
Journal Article -
9
Compression ultrasonography for diagnostic management of patients with clinically suspected deep vein thrombosis: prospective cohort study
Published in BMJ (03-01-1998)“…Abstract Objective: To evaluate the safety of withholding anticoagulant treatment from patients with clinically suspected deep vein thrombosis but normal…”
Get full text
Journal Article -
10
Rivaroxaban: Population Pharmacokinetic Analyses in Patients Treated for Acute Deep-Vein Thrombosis and Exposure Simulations in Patients with Atrial Fibrillation Treated for Stroke Prevention
Published in Clinical pharmacokinetics (01-10-2011)“…Background and Objective: Rivaroxaban is an oral, direct Factor Xa inhibitor, which is at an advanced stage of clinical development for prevention and…”
Get full text
Journal Article -
11
Clinical presentation and therapeutic management of venous thrombosis in young children: a retrospective analysis
Published in Thrombosis journal (01-11-2018)“…Venous thromboembolism (VTE) in young children is not well documented. Clinicians from 12 institutions retrospectively evaluated the presentation, therapeutic…”
Get full text
Journal Article -
12
Bleeding risk of patients with acute venous thromboembolism taking nonsteroidal anti-inflammatory drugs or aspirin
Published in JAMA internal medicine (01-06-2014)“…Combined anticoagulant and aspirin therapy is associated with increased bleeding risk in patients with atrial fibrillation, but the bleeding risk of combined…”
Get more information
Journal Article -
13
PK/PD modeling of FXI antisense oligonucleotides to bridge the dose‐FXI activity relation from healthy volunteers to end‐stage renal disease patients
Published in CPT: pharmacometrics and systems pharmacology (01-08-2021)“…IONIS‐FXIRX (BAY2306001) is an antisense oligonucleotide that inhibits the synthesis of coagulation factor XI (FXI) and has been investigated in healthy…”
Get full text
Journal Article -
14
A dose-ranging study evaluating once-daily oral administration of the factor Xa inhibitor rivaroxaban in the treatment of patients with acute symptomatic deep vein thrombosis: the Einstein–DVT Dose-Ranging Study
Published in Blood (15-09-2008)“…We performed a randomized dose-ranging study, double-blind for rivaroxaban doses and open-label for the comparator (low-molecular-weight heparin followed by…”
Get full text
Journal Article -
15
Family history of venous thrombosis or sudden death as a risk factor for venous thromboembolism
Published in Thrombosis and haemostasis (01-06-2012)Get more information
Journal Article -
16
Long-Term Risk for Major Bleeding During Extended Oral Anticoagulant Therapy for First Unprovoked Venous Thromboembolism : A Systematic Review and Meta-analysis
Published in Annals of internal medicine (01-10-2021)“…The long-term risk for major bleeding in patients receiving extended (beyond the initial 3 to 6 months) anticoagulant therapy for a first unprovoked venous…”
Get full text
Journal Article -
17
Prevalence of Pulmonary Embolism among Patients Hospitalized for Syncope
Published in The New England journal of medicine (20-10-2016)“…Among 560 patients hospitalized for syncope, 97 (17.3%) received a diagnosis of pulmonary embolism. In 61 patients, the most proximal location of the embolus…”
Get full text
Journal Article -
18
Reduction in the length of stay with rivaroxaban as a single-drug regimen for the treatment of deep vein thrombosis and pulmonary embolism
Published in Current medical research and opinion (01-05-2014)“…Abstract Objective: The phase III EINSTEIN DVT and EINSTEIN PE trials demonstrated the potential of oral rivaroxaban for the treatment of deep vein thrombosis…”
Get full text
Journal Article -
19
Deep-vein thrombosis
Published in The Lancet (British edition) (06-02-1999)“…Deep-vein thrombosis is an important complication of several inherited and acquired disorders, but may also occur spontaneously. Prevention of recurrent venous…”
Get full text
Journal Article -
20
D-dimer testing as an adjunct to ultrasonography in patients with clinically suspected deep vein thrombosis: prospective cohort study
Published in BMJ (17-10-1998)“…Abstract Objective To investigate the efficacy of using a rapid plasma D-dimer test as an adjunct to compression ultrasound for diagnosing clinically suspected…”
Get full text
Journal Article