Search Results - "Lennox, A."

Cellular localization of long non-coding RNAs affects silencing by RNAi more than by antisense oligonucleotides by Lennox, Kim A, Behlke, Mark A

“…Thousands of long non-coding RNAs (lncRNAs) have been identified in mammalian cells. Some have important functions and their dysregulation can contribute to a…”
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Adding Value to Power Station Captured CO2: Tolerant Zn and Mg Homogeneous Catalysts for Polycarbonate Polyol Production by Chapman, A. M, Keyworth, C, Kember, M. R, Lennox, A. J. J, Williams, C. K

“…Using captured waste carbon dioxide (CCU) as a chemical reagent is an attractive means to add value to carbon capture and storage (CCS) and is a high-priority…”
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Social activity and relationship changes experienced by people with bowel and bladder dysfunction following spinal cord injury by Braaf, S, Lennox, A, Nunn, A, Gabbe, B

“…Study design: Exploratory qualitative. Objectives: The aim of this study was to describe the experiences of bowel and bladder dysfunction on social activities…”
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Change is needed to diversify space science — and it starts with a name by Lennox, A. R.

“…The current naming conventions for planetary features exacerbate the underrepresentation in space science of women and marginalized groups…”
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A Direct Comparison of Anti-microRNA Oligonucleotide Potency by Lennox, Kim A., Behlke, Mark A.

“…ABSTRACT Purpose Cataloguing endogenous miRNA targets by inhibiting miRNA function is fundamental to understanding the biological importance of each miRNA in…”
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Granzyme B inhibition reduces disease severity in autoimmune blistering diseases by Hiroyasu, Sho, Zeglinski, Matthew R., Zhao, Hongyan, Pawluk, Megan A., Turner, Christopher T., Kasprick, Anika, Tateishi, Chiharu, Nishie, Wataru, Burleigh, Angela, Lennox, Peter A., Van Laeken, Nancy, Carr, Nick J., Petersen, Frank, Crawford, Richard I., Shimizu, Hiroshi, Tsuruta, Daisuke, Ludwig, Ralf J., Granville, David J.

“…Pemphigoid diseases refer to a group of severe autoimmune skin blistering diseases characterized by subepidermal blistering and loss of dermal-epidermal…”
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Structure and activity of putative intronic miRNA promoters by Monteys, Alex Mas, Spengler, Ryan M, Wan, Ji, Tecedor, Luis, Lennox, Kimberly A, Xing, Yi, Davidson, Beverly L

“…MicroRNAs (miRNAs) are RNA sequences of approximately 22 nucleotides that mediate post-transcriptional regulation of specific mRNAs. miRNA sequences are…”
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In vivo SELEX for Identification of Brain-penetrating Aptamers by Cheng, Congsheng, Chen, Yong Hong, Lennox, Kim A, Behlke, Mark A, Davidson, Beverly L

“…The physiological barriers of the brain impair drug delivery for treatment of many neurological disorders. One delivery approach that has not been investigated…”
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Melatonin as a treatment for mood disorders: a systematic review by De Crescenzo, F., Lennox, A., Gibson, J. C., Cordey, J. H., Stockton, S., Cowen, P. J., Quested, D. J.

“…Objective Melatonin has been widely studied in the treatment of sleep disorders and evidence is accumulating on a possible role for melatonin influencing mood…”
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Improved Performance of Anti-miRNA Oligonucleotides Using a Novel Non-Nucleotide Modifier by Lennox, Kim A, Owczarzy, Richard, Thomas, Derek M, Walder, Joseph A, Behlke, Mark A

“…Anti-microRNA oligonucleotides (AMOs) are steric blocking antisense reagents that inhibit microRNA (miRNA) function by hybridizing and repressing the activity…”
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Pancreas-enriched miRNA refines endocrine cell differentiation by Kredo-Russo, Sharon, Mandelbaum, Amitai D, Ness, Avital, Alon, Ilana, Lennox, Kim A, Behlke, Mark A, Hornstein, Eran

“…Genome-encoded microRNAs (miRNAs) provide a post-transcriptional regulatory layer that is important for pancreas development. However, how specific miRNAs are…”
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microRNA network regulates expression and biosynthesis of wild-type and ΔF508 mutant cystic fibrosis transmembrane conductance regulator by Ramachandran, Shyam, Karp, Philip H, Jiang, Peng, Ostedgaard, Lynda S, Walz, Amy E, Fisher, John T, Keshavjee, Shaf, Lennox, Kim A, Jacobi, Ashley M, Rose, Scott D, Behlke, Mark A, Welsh, Michael J, Xing, Yi, McCray, Paul B

“…Production of functional proteins requires multiple steps, including gene transcription and posttranslational processing. MicroRNAs (miRNAs) can regulate…”
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Human genetics and neuropathology suggest a link between miR-218 and amyotrophic lateral sclerosis pathophysiology by Reichenstein, Irit, Eitan, Chen, Diaz-Garcia, Sandra, Haim, Guy, Magen, Iddo, Siany, Aviad, Hoye, Mariah L, Rivkin, Natali, Olender, Tsviya, Toth, Beata, Ravid, Revital, Mandelbaum, Amitai D, Yanowski, Eran, Liang, Jing, Rymer, Jeffrey K, Levy, Rivka, Beck, Gilad, Ainbinder, Elena, Farhan, Sali M K, Lennox, Kimberly A, Bode, Nicole M, Behlke, Mark A, Möller, Thomas, Saxena, Smita, Moreno, Cristiane A M, Costaguta, Giancarlo, van Eijk, Kristel R, Phatnani, Hemali, Al-Chalabi, Ammar, Başak, A Nazli, van den Berg, Leonard H, Hardiman, Orla, Landers, John E, Mora, Jesus S, Morrison, Karen E, Shaw, Pamela J, Veldink, Jan H, Pfaff, Samuel L, Yizhar, Ofer, Gross, Christina, Brown, Jr, Robert H, Ravits, John M, Harms, Matthew B, Miller, Timothy M, Hornstein, Eran

“…Motor neuron-specific microRNA-218 (miR-218) has recently received attention because of its roles in mouse development. However, miR-218 relevance to human…”
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Bicep/Keck XV: The Bicep3 Cosmic Microwave Background Polarimeter and the First Three-year Data Set by Ade, P. A. R., Ahmed, Z., Amiri, M., Barkats, D., Thakur, R. Basu, Bischoff, C. A., Beck, D., Bock, J. J., Boenish, H., Bullock, E., Buza, V., Cheshire IV, J. R., Connors, J., Cornelison, J., Crumrine, M., Cukierman, A., Denison, E. V., Dierickx, M., Duband, L., Eiben, M., Fatigoni, S., Filippini, J. P., Fliescher, S., Goeckner-Wald, N., Goldfinger, D. C., Grayson, J., Grimes, P., Hall, G., Halal, G., Halpern, M., Hand, E., Harrison, S., Henderson, S., Hildebrandt, S. R., Hilton, G. C., Hubmayr, J., Hui, H., Irwin, K. D., Kang, J., Karkare, K. S., Karpel, E., Kefeli, S., Kernasovskiy, S. A., Kovac, J. M., Kuo, C. L., Lau, K., Leitch, E. M., Lennox, A., Megerian, K. G., Minutolo, L., Moncelsi, L., Nakato, Y., Namikawa, T., Nguyen, H. T., O’Brient, R., Ogburn IV, R. W., Palladino, S., Prouve, T., Pryke, C., Racine, B., Reintsema, C. D., Richter, S., Schillaci, A., Schwarz, R., Schmitt, B. L., Sheehy, C. D., Soliman, A., Germaine, T. St, Steinbach, B., Sudiwala, R. V., Teply, G. P., Thompson, K. L., Tolan, J. E., Tucker, C., Turner, A. D., Umiltà, C., Vergès, C., Vieregg, A. G., Wandui, A., Weber, A. C., Wiebe, D. V., Willmert, J., Wong, C. L., Wu, W. L. K., Yang, H., Yoon, K. W., Young, E., Yu, C., Zeng, L., Zhang, C., Zhang, S.

“…Abstract We report on the design and performance of the B icep3 instrument and its first three-year data set collected from 2016 to 2018. B icep3 is a 52 cm…”
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Granzyme B is elevated in autoimmune blistering diseases and cleaves key anchoring proteins of the dermal-epidermal junction by Russo, Valerio, Klein, Theo, Lim, Darielle J., Solis, Nestor, Machado, Yoan, Hiroyasu, Sho, Nabai, Layla, Shen, Yue, Zeglinski, Matthew R., Zhao, Hongyan, Oram, Cameron P., Lennox, Peter A., Van Laeken, Nancy, Carr, Nick J., Crawford, Richard I., Franzke, Claus-Werner, Overall, Christopher M., Granville, David J.

“…In healthy skin, epidermis and dermis are anchored together at the dermal-epidermal junction (DEJ), a specialized basement membrane pivotal for skin integrity…”
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Sequence-dependent inhibition of cGAS and TLR9 DNA sensing by 2′-O-methyl gapmer oligonucleotides by Valentin, Roxane, Wong, Christophe, Alharbi, Arwaf S, Pradeloux, Solène, Morros, Makala P, Lennox, Kim A, Ellyard, Julia I, Garcin, Aurélie J, Ullah, Tomalika R, Kusuma, Gina D, Pépin, Geneviève, Li, Hong-Mei, Pearson, Jaclyn S, Ferrand, Jonathan, Lim, Rebecca, Veedu, Rakesh N, Morand, Eric F, Vinuesa, Carola G, Behlke, Mark A, Gantier, Michael P

“…Abstract Oligonucleotide-based therapeutics have the capacity to engage with nucleic acid immune sensors to activate or block their response, but a detailed…”
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BICEP/Keck. XVI. Characterizing Dust Polarization through Correlations with Neutral Hydrogen by Ade, P. A. R., Ahmed, Z., Amiri, M., Barkats, D., Thakur, R. Basu, Bischoff, C. A., Beck, D., Bock, J. J., Boenish, H., Bullock, E., Buza, V., Cheshire, J. R., Clark, S. E., Connors, J., Cornelison, J., Crumrine, M., Cukierman, A., Denison, E. V., Dierickx, M., Duband, L., Eiben, M., Fatigoni, S., Filippini, J. P., Fliescher, S., Giannakopoulos, C., Goeckner-Wald, N., Goldfinger, D. C., Grayson, J., Grimes, P., Hall, G., Halal, G., Halpern, M., Hand, E., Harrison, S., Henderson, S., Hildebrandt, S. R., Hubmayr, J., Hui, H., Irwin, K. D., Kang, J., Karkare, K. S., Karpel, E., Kefeli, S., Kernasovskiy, S. A., Kovac, J. M., Kuo, C. L., Lau, K., Leitch, E. M., Lennox, A., Megerian, K. G., Minutolo, L., Moncelsi, L., Nakato, Y., Namikawa, T., Nguyen, H. T., O’Brient, R., IV, R. W. Ogburn, Palladino, S., Petroff, M. A., Prouve, T., Pryke, C., Racine, B., Reintsema, C. D., Richter, S., Schillaci, A., Schwarz, R., Schmitt, B. L., Sheehy, C. D., Singari, B., Soliman, A., Germaine, T. St, Steinbach, B., Sudiwala, R. V., Teply, G. P., Thompson, K. L., Tolan, J. E., Tucker, C., Turner, A. D., Umiltà, C., Vergès, C., Vieregg, A. G., Wandui, A., Weber, A. C., Wiebe, D. V., Willmert, J., Wong, C. L., Wu, W. L. K., Yang, H., Yoon, K. W., Young, E., Yu, C., Zeng, L., Zhang, C., Zhang, S.

“…Abstract We characterize Galactic dust filaments by correlating BICEP/Keck and Planck data with polarization templates based on neutral hydrogen (H i )…”
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BICEP/Keck. XVII. Line-of-sight Distortion Analysis: Estimates of Gravitational Lensing, Anisotropic Cosmic Birefringence, Patchy Reionization, and Systematic Errors by Ade, P. A. R., Ahmed, Z., Amiri, M., Barkats, D., Thakur, R. Basu, Bischoff, C. A., Beck, D., Bock, J. J., Boenish, H., Bullock, E., Buza, V., IV, J. R. Cheshire, Connors, J., Cornelison, J., Crumrine, M., Cukierman, A., Denison, E. V., Dierickx, M., Duband, L., Eiben, M., Fatigoni, S., Filippini, J. P., Fliescher, S., Giannakopoulos, C., Goeckner-Wald, N., Goldfinger, D. C., Grayson, J., Grimes, P., Hall, G., Halal, G., Halpern, M., Hand, E., Harrison, S., Henderson, S., Hildebrandt, S. R., Hubmayr, J., Hui, H., Irwin, K. D., Kang, J., Karkare, K. S., Karpel, E., Kefeli, S., Kernasovskiy, S. A., Kovac, J. M., Kuo, C. L., Lau, K., Leitch, E. M., Lennox, A., Megerian, K. G., Minutolo, L., Moncelsi, L., Nakato, Y., Namikawa, T., Nguyen, H. T., O’Brient, R., IV, R. W. Ogburn, Palladino, S., Petroff, M., Prouve, T., Pryke, C., Racine, B., Reintsema, C. D., Richter, S., Schillaci, A., Schwarz, R., Schmitt, B. L., Sheehy, C. D., Singari, B., Soliman, A., Germaine, T. St, Steinbach, B., Sudiwala, R. V., Teply, G. P., Thompson, K. L., Tolan, J. E., Tucker, C., Turner, A. D., Umiltà, C., Vergès, C., Vieregg, A. G., Wandui, A., Weber, A. C., Wiebe, D. V., Willmert, J., Wong, C. L., Wu, W. L. K., Yang, H., Yoon, K. W., Young, E., Yu, C., Zeng, L., Zhang, C., Zhang, S.

“…Abstract We present estimates of line-of-sight distortion fields derived from the 95 and 150 GHz data taken by BICEP2, BICEP3, and the Keck Array up to the…”
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Advanced diagnostic imaging and surgical treatment of an odontogenic retromasseteric abscess in a guinea pig by Capello, V., Lennox, A.

“…A two‐year‐old guinea pig presented for difficulty chewing. Examination and diagnostic imaging, including computed tomography and magnetic resonance, revealed…”
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Antisense Oligonucleotide-Mediated Transcript Knockdown in Zebrafish by Pauli, Andrea, Montague, Tessa G, Lennox, Kim A, Behlke, Mark A, Schier, Alexander F

“…Antisense oligonucleotides (ASOs) are synthetic, single-strand RNA-DNA hybrids that induce catalytic degradation of complementary cellular RNAs via RNase H…”
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