Search Results - "Lenkei, Zsolt"
-
1
Ultrafast ultrasound localization microscopy for deep super-resolution vascular imaging
Published in Nature (London) (26-11-2015)“…Conventional clinical ultrasound imaging has, at best, sub-millimetre-scale resolution, but now a new ultrasound technique is demonstrated that is based on…”
Get full text
Journal Article -
2
Small and Stable Sulfobetaine Zwitterionic Quantum Dots for Functional Live-Cell Imaging
Published in Journal of the American Chemical Society (07-04-2010)“…We have developed a novel surface coating for semiconductor quantum dots (QDs) based on a heterobifunctional ligand that overcomes most of the previous limits…”
Get full text
Journal Article -
3
Transcranial functional ultrasound imaging of the brain using microbubble-enhanced ultrasensitive Doppler
Published in NeuroImage (Orlando, Fla.) (01-01-2016)“…Functional ultrasound (fUS) is a novel neuroimaging technique, based on high-sensitivity ultrafast Doppler imaging of cerebral blood volume, capable of…”
Get full text
Journal Article -
4
Pharmaco-fUS: Quantification of pharmacologically-induced dynamic changes in brain perfusion and connectivity by functional ultrasound imaging in awake mice
Published in NeuroImage (Orlando, Fla.) (15-11-2020)“…•fUS imaging estimates the functional connectivity brain networks at very high spatial resolution (100 × 100 × 400 µm) in awake and behaving mice.•Pharmaco-fUS…”
Get full text
Journal Article -
5
Ultrafast ultrasound imaging pattern analysis reveals distinctive dynamic brain states and potent sub-network alterations in arthritic animals
Published in Scientific reports (26-06-2020)“…Chronic pain pathologies, which are due to maladaptive changes in the peripheral and/or central nervous systems, are debilitating diseases that affect 20% of…”
Get full text
Journal Article -
6
Cannabinoid-induced actomyosin contractility shapes neuronal morphology and growth
Published in eLife (15-09-2014)“…Endocannabinoids are recently recognized regulators of brain development, but molecular effectors downstream of type-1 cannabinoid receptor (CB1R)-activation…”
Get full text
Journal Article -
7
A highly soluble, non-phototoxic, non-fluorescent blebbistatin derivative
Published in Scientific reports (31-05-2016)“…Blebbistatin is a commonly used molecular tool for the specific inhibition of various myosin II isoforms both in vitro and in vivo . Despite its popularity,…”
Get full text
Journal Article -
8
Actomyosin-mediated inhibition of synaptic vesicle release under CB1R activation
Published in Translational psychiatry (21-08-2024)“…Long-term synaptic plasticity is critical for adaptive function of the brain, but presynaptic mechanisms of functional plasticity remain poorly understood…”
Get full text
Journal Article -
9
BDNF-dependent plasticity induced by peripheral inflammation in the primary sensory and the cingulate cortex triggers cold allodynia and reveals a major role for endogenous BDNF as a tuner of the affective aspect of pain
Published in The Journal of neuroscience (29-10-2014)“…Painful experiences are multilayered, composed of sensory, affective, cognitive and behavioral facets. Whereas it is well accepted that the development of…”
Get full text
Journal Article -
10
Type-1 cannabinoid receptor signaling in neuronal development
Published in Pharmacology (01-01-2012)“…The type-1 cannabinoid receptor (CB1R) was initially identified as the neuronal target of Δ(9)-tetrahydrocannabinol (THC), the major psychoactive substance of…”
Get more information
Journal Article -
11
Activation-dependent subcellular distribution patterns of CB1 cannabinoid receptors in the rat forebrain
Published in Cerebral cortex (New York, N.Y. 1991) (01-11-2013)“…Chronic cannabinoid exposure results in tolerance due to region-specific desensitization and down-regulation of CB1 cannabinoid receptors (CB1Rs). For most…”
Get full text
Journal Article -
12
SponGee: A Genetic Tool for Subcellular and Cell-Specific cGMP Manipulation
Published in Cell reports (Cambridge) (25-06-2019)“…cGMP is critical to a variety of cellular processes, but the available tools to interfere with endogenous cGMP lack cellular and subcellular specificity. We…”
Get full text
Journal Article -
13
Orofacial Neuropathic Pain Leads to a Hyporesponsive Barrel Cortex with Enhanced Structural Synaptic Plasticity
Published in PloS one (22-08-2016)“…Chronic pain is a long-lasting debilitating condition that is particularly difficult to treat due to the lack of identified underlying mechanisms. Although…”
Get full text
Journal Article -
14
Constitutive Endocytic Cycle of the CB1 Cannabinoid Receptor
Published in The Journal of biological chemistry (20-08-2004)“…The CB1 cannabinoid receptor (CB1R) displays a significant level of ligand-independent ( i.e. constitutive) activity, either when heterologously expressed in…”
Get full text
Journal Article -
15
UNRAVELLING THE ROLE OF 5-HT2AR ACTIVATION IN THE LONG-LASTING BEHAVIORAL EFFECTS OF PSILOCYBIN
Published in IBRO neuroscience reports (01-10-2023)Get full text
Journal Article -
16
Constitutive Activation Drives Compartment-Selective Endocytosis and Axonal Targeting of Type 1 Cannabinoid Receptors
Published in The Journal of neuroscience (22-03-2006)“…The type 1 cannabinoid receptor (CB1R) is one of the most abundant G-protein-coupled receptors (GPCRs) in the brain, predominantly localized to axons of…”
Get full text
Journal Article -
17
Cannabinoid receptor activation in the juvenile rat brain results in rapid biomechanical alterations: Neurovascular mechanism as a putative confounding factor
Published in Journal of cerebral blood flow and metabolism (01-05-2016)“…We have recently reported cannabinoid-induced rapid changes in the structure of individual neurons. In order to investigate the presence of similar effects at…”
Get full text
Journal Article -
18
Neuron-to-Neuron Transfer of FUS in Drosophila Primary Neuronal Culture Is Enhanced by ALS-Associated Mutations
Published in Journal of molecular neuroscience (01-05-2017)“…The DNA- and RNA-binding protein fused in sarcoma (FUS) has been pathologically and genetically linked to amyotrophic lateral sclerosis (ALS) or frontotemporal…”
Get full text
Journal Article -
19
Physiological role of a novel neuropeptide, apelin, and its receptor in the rat brain
Published in Journal of neurochemistry (01-05-2001)“…Apelin, a peptide recently isolated from bovine stomach tissue extracts, has been identified as the endogenous ligand of the human orphan APJ receptor. We…”
Get full text
Journal Article -
20
Cloning, pharmacological characterization and brain distribution of the rat apelin receptor
Published in Neuroendocrinology (01-12-2000)“…The peptide apelin, recently isolated from bovine stomach tissue extracts, has been identified as an endogenous ligand of the human putative receptor protein…”
Get more information
Journal Article