Search Results - "Lenglet, S."

Pharmacokinetics and biodistribution study of self-assembled Gd-micelles demonstrating blood-pool contrast enhancement for MRI by Vorobiev, V., Babič, A., Crowe, L.A., Van De Looij, Y., Lenglet, S., Thomas, A., Helm, L., Vallée, J.-P., Allémann, E.

“…[Display omitted] Magnetic resonance angiography (MRA) requires the use of contrast agents (CAs) to enable accurate diagnosis. There are currently no CAs on…”
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Impact of Functional Allelic Variations on Drug-Drug Interactions Involving CYP2D6 by Storelli, F, Matthey, A, Lenglet, S, Thomas, A, Daali, Y, Desmeules, J

“…Currently phenotypes of carriers of two fully-functional alleles (genetic activity score 2, gAS2) and carriers of one fully-functional and one non-functional…”
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Anti-apoA-1 autoantibodies increase mouse atherosclrotic plaque vulnerability, myocardial necrosis and mortality trough TLR2 and TLR4-mediated pathways by Montecucco, F, Braunersreuther, V, Burger, F, Lenglet, S, Pelli, G, Carbone, F, Fraga-Silva, R, Stergiopulos, N, Monaco, C, Mueller, C, Pagano, S, Dallegri, F, Mach, F, Vuilleumier, N

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O043 Treatment with chemokine-binding protein Evasin-3 reduces atherosclerotic vulnerability for ischemic stroke in mice by Montecucco, F., da Silva, R., Fraga-Silva, R.A., Capettini, L., Quintao, S., Lenglet, S., Pelli, G., Galan, K., Braunersreuther, V., Schaller, K., Proudfoot, A.E., Stergiopulos, N., Santos, R.A., Gasche, Y., Mach, F., Copin, J.-C.

“…The presence and rupture of a carotid plaque inducing a severe arterial lumen stenosis have been associated with a consequent acute ischemic stroke in the…”
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INVOLVEMENT OF T-TYPE CALCIUM CHANNELS IN THE CHRONOTROPIC ACTION OF STEROIDS ON THE HEART by Maturana, A.D, Lenglet, S, Vetterli, L, Chau-Van, C, Python, M, Rossier, M.F

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Impact of CYP2D6 Functional Allelic Variations on Phenoconversion and Drug–Drug Interactions by Storelli, Flavia, Matthey, Alain, Lenglet, Sébastien, Thomas, Aurélien, Desmeules, Jules, Daali, Youssef

“…We investigated whether CYP2D6 extensive metabolizers carrying a nonfunctional allele are at higher risk of phenoconversion to poor metabolizers in the…”
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Role of 5-HT in the regulation of the brain-pituitary-adrenal axis: effects of 5-HT on adrenocortical cells by Contesse, V, Lefebvre, H, Lenglet, S, Kuhn, J M, Delarue, C, Vaudry, H

“…Serotonin (5-HT) plays a pivotal role in the regulation of the brain-pituitary-adrenal axis. In particular, 5-HT has been shown to control the activity of…”
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P07-24 Cadmium-induced inflammation in human adipocytes and macrophages by Gasser, M., Lenglet, S., Bararpour, N., Wiskott, K., Augsburger, M., Fracasso, T., Gilardi, F., Thomas, A.

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INVOLVEMENT OF T-TYPE CALCIUM CHANNELS IN THE MECHANISM OF ACTION OF 5-HT IN RAT GLOMERULOSA CELLS: A NOVEL SIGNALING PATHWAY FOR THE 5-HT7 RECEPTOR by Lenglet, S., Louiset, E., Delarue, C., Vaudry, H., Contesse, V.

“…We have previously demonstrated that, in rat, the stimulatory effect of 5-HT on aldosterone secretion is mediated through a 5-HT7 receptor subtype. The aim of…”
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Analysis of the expression of nine secreted matrix metalloproteinases and their endogenous inhibitors in the brain of mice subjected to ischaemic stroke by Lenglet, S, Montecucco, F, Mach, F, Schaller, K, Gasche, Y, Copin, J-C

“…Matrix metalloproteinases (MMPs) are a family of more than twenty secreted and cell-surface endopeptidases. Among them, MMP2, MMP3 and MMP9 are involved in…”
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Pharmacological inhibition of monoacylglycerol lipase enhances IGM plasma levels and limits atherogenesis in a CB2-dependent manner by Guillamat-prats, R., Rami, M., Ring, L., Rinne, P., Lenglet, S., Lauer, E., Thomas, A., Cravatt, B., Weber, C., Faussner, A., Steffens, S.

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Anti-apoA-1 auto-antibodies increase mouse atherosclerotic plaque vulnerability, myocardial necrosis and mortality triggering TLR2 and TLR4 by Montecucco, F, Braunersreuther, V, Burger, F, Lenglet, S, Pelli, G, Carbone, F, Fraga-Silva, R, Stergiopulos, N, Monaco, C, Mueller, C, Pagano, S, Dallegri, F, Mach, F, Vuilleumier, N

“…Auto-antibodies to apolipoprotein A-1 (anti-apoA-1 IgG) were shown to promote inflammation and atherogenesis, possibly through innate immune receptors…”
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Toll-Like Receptor 7 Protects From Atherosclerosis by Constraining Inflammatory Macrophage Activation by SALAGIANNI, Maria, GALANI, Ioanna E, GORGOULIS, Vassilis, LENGLET, Sebastien, MONTECUCCO, Fabrizio, MACH, François, HEDIN, Ulf, HANSSON, Göran K, MONACO, Claudia, ANDREAKOS, Evangelos, LUNDBERG, Anna M, DAVOS, Constantinos H, VARELA, Aimilia, GAVRIIL, Ariana, LYYTIKAINEN, Leo-Pekka, LEHTIMAKI, Terho, SIGALA, Fragiska, FOLKERSEN, Lasse

“…Toll-like receptors (TLRs) have long been considered to be major culprits in the development of atherosclerosis, contributing both to its progression and…”
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Low plasma zinc levels (but not selenium) are associated with anti-SARS-COV-2 IGG and IGA seropositivity in the general population: A case-control study by Equey, A., Berger, M.M., Gonseth-Nusslé, S., Augsburger, M., Rezzi, S., Hodgson, A.C., Estoppey, S., Pantaleo, G., Pellaton, C., Perrais, M., Lenglet, S., Rousson, V., D'Acremont, V., Bochud, M.

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Nicotinamide phosphoribosyltransferase inhibition reduces intraplaque CXCL1 production and associated neutrophil infiltration in atherosclerotic mice by Nencioni, Alessio, da Silva, Rafaela F, Fraga-Silva, Rodrigo A, Steffens, Sabine, Fabre, Mathias, Bauer, Inga, Caffa, Irene, Magnone, Mirko, Sociali, Giovanna, Quercioli, Alessandra, Pelli, Graziano, Lenglet, Sébastien, Galan, Katia, Burger, Fabienne, Vázquez Calvo, Sara, Bertolotto, Maria, Bruzzone, Santina, Ballestrero, Alberto, Patrone, Franco, Dallegri, Franco, Santos, Robson A, Stergiopulos, Nikolaos, Mach, François, Vuilleumier, Nicolas, Montecucco, Fabrizio

“…Pharmacological treatments targeting CXC chemokines and the associated neutrophil activation and recruitment into atherosclerotic plaques hold promise for…”
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Rat Glomerulosa Cells Express Functional 5-HT7 Receptors by Lenglet, S., Delarue, C., Lefebvre, H., Vaudry, H., Contesse, V.

“…It has been previously demonstrated that serotonin (5-HT) is a potent stimulator of aldosterone secretion in amphibians and mammals. The aim of the present…”
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Mass spectrometry for the evaluation of cardiovascular diseases based on proteomics and lipidomics by Thomas, Aurélien, Lenglet, Sébastien, Chaurand, Pierre, Deglon, Julien, Mangin, Patrice, Mach, François, Steffens, Sabine, Wolfender, Jean-Luc, Staub, Christian

“…The identification and quantification of proteins and lipids is of major importance for the diagnosis, prognosis and understanding of the molecular mechanisms…”
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Molecular imaging of matrix metalloproteinases in atherosclerotic plaques by Lenglet, Sébastien, Thomas, Aurélien, Chaurand, Pierre, Galan, Katia, Mach, François, Montecucco, Fabrizio

“…Ischaemic stroke and myocardial infarction often result from the sudden rupture of an atherosclerotic plaque. The subsequent arterial thrombosis occluding the…”
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Syndrome des ongles jaunes et exposition au dioxyde de titane by Marescassier, H.-A., Laffitte, E., Fontao, L., Lenglet, S.

“…Le syndrome des ongles jaunes ou « yellow nail syndrome » (YNS) est une entité rare qui correspond à l’association de dystrophies unguéales (ongles épaissis,…”
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Receptor activator of NF- κB ligand (RANKL) increases the release of neutrophil products associated with coronary vulnerability by Quercioli, Alessandra, Mach, François, Bertolotto, Maria, Lenglet, Sébastien, Vuilleumier, Nicolas, Galan, Katia, Pagano, Sabrina, Braunersreuther, Vincent, Pelli, Graziano, Pistoia, Vito, Bianchi, Giovanna, Cittadini, Giuseppe, Viviani, Giorgio Luciano, Pende, Aldo, Roux-Lombard, Pascale, Thomas, Aurélien, Staub, Christian, Ratib, Osman, Dallegri, Franco, Schindler, Thomas Helmut, Montecucco, Fabrizio

“…The "blood vulnerability", resulting from the complex balance between serum molecules and inflammatory cell atherosclerotic activities, is a major determinant…”
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