Search Results - "Lengauer, C."

Coherent solvus of disordered alkali feldspar: experiment, atom probe tomography and thermodynamic model by Heuser, D., Dubosq, R., Petrishcheva, E., Bian, G., Rentenberger, C., Lengauer, C. L., Gault, B., Habler, G., Abart, R.

“…At temperatures above about 600 °C, alkali feldspar forms a continuous solid solution between the Na and K end members. Towards lower temperatures a…”
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Language-Independent and Automated Software Composition: The FeatureHouse Experience by Apel, S., Kastner, C., Lengauer, C.

“…Superimposition is a composition technique that has been applied successfully in many areas of software development. Although superimposition is a…”
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Thermodynamic mixing properties of disordered alkali feldspar solid-solution from Na–K partitioning and low-temperature calorimetry by Heuser, D., Petrishcheva, E., Ingegneri, F., Lengauer, C. L., Dachs, E., Hauzenberger, C., Abart, R.

“…The equilibrium partitioning of Na and K between alkali feldspar and NaCl–KCl salt melt was determined at 800 ∘ C, 850 ∘ C, 900 ∘ C, 950 ∘ C and 1000 ∘ C and…”
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Genetic instability in colorectal cancers by Lengauer, C, Kinzler, K. W, Vogelstein, B

“…It has long been considered that genetic instability is an integral component of human neoplasia. In a small fraction of tumours, mismatch repair deficiency…”
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Requirement for p53 and p21 to sustain G2 arrest after DNA damage by BUNZ, F, DUTRIAUX, A, LENGAUER, C, WALDMAN, T, ZHOU, S, BROWN, J. P, SEDIVY, J. M, KINZLER, K. W, VOGELSTEIN, B

“…After DNA damage, many cells appear to enter a sustained arrest in the G2 phase of the cell cycle. It is shown here that this arrest could be sustained only…”
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A Phosphatase Associated with Metastasis of Colorectal Cancer by Saha, Saurabh, Bardelli, Alberto, Buckhaults, Phillip, Velculescu, Victor E., Rago, Carlo, St. Croix, Brad, Romans, Katharine E., Choti, Michael A., Lengauer, Christoph, Kinzler, Kenneth W., Vogelstein, Bert

“…To gain insights into the molecular basis for metastasis, we compared the global gene expression profile of metastatic colorectal cancer with that of primary…”
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Genes Expressed in Human Tumor Endothelium by St. Croix, Brad, Rago, Carlo, Velculescu, Victor, Traverso, Giovanni, Romans, Katharine E., Montgomery, Elizabeth, Lal, Anita, Riggins, Gregory J., Lengauer, Christoph, Vogelstein, Bert, Kinzler, Kenneth W.

“…To gain a molecular understanding of tumor angiogenesis, we compared gene expression patterns of endothelial cells derived from blood vessels of normal and…”
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Evidence that genetic instability occurs at an early stage of colorectal tumorigenesis by SHIH, Ie-Ming, WEI ZHOU, GOODMAN, Steven N, LENGAUER, Christoph, KINZLER, Kenneth W, VOGELSTEIN, Bert

“…Chromosomal instability is believed to be a common feature of most human tumors, but the stage at which such instability originates has not been defined. At…”
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O048 : First selective small molecule inhibitor of FGFR4 for the treatment of hepatocellular carcinomas with an activated FGFR4 signaling pathway by Hoeflich, K, Hagel, M, Miduturu, C, Sheets, M, Rubin, N, Weng, W, Stransky, N, Bifulco, N, Kim, J, Hodous, B, Brooijmans, N, Shutes, A, Winter, C, Lengauer, C, Kohl, N, Guzi, T

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Cdc6 is an unstable protein whose de novo synthesis in G1 is important for the onset of S phase and for preventing a 'reductional' anaphase in the budding yeast Saccharomyces cerevisiae by Piatti, S, Lengauer, C, Nasmyth, K

“…S phase entry depends on cyclin-dependent kinases whose activation during late G1 is due partly to the synthesis of unstable cyclin subunits. We identify here…”
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Comparative Genome Map of Human and Cattle by Solinas-Toldo, Sabina, Lengauer, Christoph, Fries, Ruedi

“…Chromosomal homologies between individual human chromosomes and the bovine karyotype have been established by using a new approach termed Zoo-FISH. Labeled DNA…”
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Evaluation of candidate tumour suppressor genes on chromosome 18 in colorectal cancers by Thiagalingam, Sam, Lengauer, Christoph, Leach, Frederick S, Schutte, Mieke, Hahn, Stephan A, Overhauser, Joan, Willson, James K.V, Markowitz, Sanford, Hamilton, Stanley R, Kern, Scott E, Kinzler, Kenneth W, Vogelstein, Bert

“…Chromosome deletions are the most common genetic events observed in cancer. These deletions are generally thought to reflect the existence of a tumour…”
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How Do Tumors Make Ends Meet? by Lengauer, Christoph

“…Specific translocations can render a selective advantage to the cell and allow the outgrowth of cancer cell clones carrying such an aberration. Lengauer…”
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Friedrichbeckeite, K (□0.5Na0.5)2 (Mg0.8Mn0.1Fe0.1)2 (Be0.6 Mg0.4)3 [Si12O30], a new milarite-type mineral from the Bellerberg volcano, Eifel area, Germany by Lengauer, C. L., Hrauda, N., Kolitsch, U., Krickl, R., Tillmanns, E.

“…Friedrichbeckeite is a new milarite-type mineral. It was found in a single silicate-rich xenolith from a quarry at the Bellerberg volcano near Ettringen,…”
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A rapid method for low-temperature synthesis of the Na analogue of the microporous titanosilicate GTS-1 by FERDOV, S, LENGAUER, C, PETROV, O, KOSTOV-KYTIN, V

“…The present paper reports a new approach for synthesis of microporous titanosilicates. We describe the synthesis of GTS-1 from a sodium gel at 90DGC after 18…”
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Aneuploidy and cancer by Lengauer, Christoph, Rajagopalan, Harith

“…In contrast to normal cells, aneuploidy--alterations in the number of chromosomes--is consistently observed in virtually all cancers. A growing body of…”
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115 Discovery and characterization of PI3Kbeta isoform-selective inhibitors by Virone-Oddos, A, Halley, F, Delorme, C, Bonnevaux, H, Nicolas, J.P, Karlsson, A, Abecassis, P.Y, Vincent, L, Lengauer, C

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Preparation and optical properties of holmium doped silica xerogels by GUTZOV, S, BERGER, C, BREDOL, M, LENGAUER, C. L

“…The optical properties of holmium doped silica xerogels were analysed with 0.5-17 mol% of holmium. Absorption spectra were used as a local environment…”
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Tl2S : Re-determination of crystal structure and stereochemical discussion by GIESTER, G, LENGAUER, C. L, TILLMANNS, E, ZEMANN, J

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73P Multi-cancer early detection through evaluation of aneuploidy, methylation, and protein biomarkers in plasma by Douville, C., Nobles, C., Hwang, H.J., Katerov, V.E., Gainullin, V., Tong, J., Ushakov, K., Koenig, A., Guttman, H., Jaime, M., Wang, J., Ault, W., Gray, M.M., Cerqueira, G.C., Lengauer, C., Garces, J., McElhinny, A., Allawi, H.T., Diehl, F.

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