Search Results - "Leng, Xigang"

Hyaluronic Acid-Modified Cationic Lipid–PLGA Hybrid Nanoparticles as a Nanovaccine Induce Robust Humoral and Cellular Immune Responses by Liu, Lanxia, Cao, Fengqiang, Liu, Xiaoxuan, Wang, Hai, Zhang, Chao, Sun, Hongfan, Wang, Chun, Leng, Xigang, Song, Cunxian, Kong, Deling, Ma, Guilei

“…Here, we investigated the use of hyaluronic acid (HA)-decorated cationic lipid–poly­(lactide-co-glycolide) acid (PLGA) hybrid nanoparticles (HA-DOTAP-PLGA NPs)…”
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A Dual‐Model Imaging Theragnostic System Based on Mesoporous Silica Nanoparticles for Enhanced Cancer Phototherapy by Huang, Chenlu, Zhang, Zhiming, Guo, Qing, Zhang, Li, Fan, Fan, Qin, Yu, Wang, Hai, Zhou, Sheng, Ou‐Yang, Wenbin, Sun, Hongfan, Leng, Xigang, Pan, Xiangbin, Kong, Deling, Zhang, Linhua, Zhu, Dunwan

“…Mesoporous silica nanoparticles (MSNs) show great promise to be exploited as versatile multifunctional nanocarriers for effective cancer diagnosis and…”
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Doxorubicin and CpG loaded liposomal spherical nucleic acid for enhanced Cancer treatment by Deng, Bo, Ma, Bing, Ma, Yingying, Cao, Pei, Leng, Xigang, Huang, Pengyu, Zhao, Yuanyuan, Ji, Tianjiao, Lu, Xueguang, Liu, Lanxia

“…Chemotherapeutics that can trigger immunogenic cell death (ICD) and release tumor-specific antigens are effective on treating a variety of cancers. The…”
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Micelle or polymersome formation by PCL-PEG-PCL copolymers as drug delivery systems by Hu, Chunyan, Chen, Zhuo, Wu, Shengjie, Han, Yanfeng, Wang, Hai, Sun, Hongfan, Kong, Deling, Leng, Xigang, Wang, Chun, Zhang, Linhua, Zhu, Dunwan

“…Polye-caprolactone）-b-poly（ethylene glycol）-b-poly（e-caprolactone）（PCL-b-PEG-b-PCL,PCEC） triblock copolymers have been widely investigated in last several…”
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Swim Bladder as a Novel Biomaterial for Cardiovascular Materials with Anti‐Calcification Properties by Liu, Jing, Li, Binhan, Jing, Huimin, Wu, Yongjian, Kong, Deling, Leng, Xigang, Wang, Zhihong

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Simultaneous monitoring of the drug release and antitumor effect of a novel drug delivery system-MWCNTs/DOX/TC by Dong, Xia, Sun, Zhiting, Wang, Xiaoxiao, Zhu, Dunwan, Liu, Lanxia, Leng, Xigang

“…Monitoring drug release and therapeutic efficacy is crucial for developing drug delivery systems. Our preliminary study demonstrated that, as compared with…”
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Carboxylation of multiwalled carbon nanotube enhanced its biocompatibility with L02 cells through decreased activation of mitochondrial apoptotic pathway by Liu, Zhenbao, Dong, Xia, Song, Liping, Zhang, Hailing, Liu, Lanxia, Zhu, Dunwan, Song, Cunxian, Leng, Xigang

“…Modification of carbon nanotubes (CNTs) with carboxyl group is one of the widely used strategies to increase their water dispersibility. Various molecules can…”
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TAT-LHRH conjugated low molecular weight chitosan as a gene carrier specific for hepatocellular carcinoma cells by Liu, Lanxia, Dong, Xia, Zhu, Dunwan, Song, Liping, Zhang, Hailing, Leng, Xigang G

“…To develop a chitosan-based nonviral gene carrier capable of delivering genes specifically into hepatoma cells, a bifunctional peptide composed of the TAT…”
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Comprehensive analyses and prioritization of various swim bladder-derived extracellular matrix in the application of heart valve prosthesis by Li, Binhan, Jing, Huimin, Sun, Zhiting, Wang, Xiaoxiao, Kong, Deling, Liu, Jing, Leng, Xigang, Wang, Zhihong

“…Calcification-caused failure and deterioration have become the biggest issues facing traditional biological heart valves (BHVs). Thus, developing new source of…”
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Arginine conjugation affects the endocytic pathways of chitosan/DNA nanoparticles by Zhang, Hailing, Zhu, Dunwan, Song, Liping, Liu, Lanxia, Dong, Xia, Liu, Zhenbao, Leng, Xigang

“…Previous reports showed that arginine‐rich peptides and oligoarginines facilitated the cellular internalization of DNA and proteins. A number of studies…”
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Highly sensitive detection of human IgG using a novel bio-barcode assay combined with DNA chip technology by Liu, Zhenbao, Zhou, Bo, Wang, Haiqing, Lu, Feng, Liu, Tianjun, Song, Cunxian, Leng, Xigang

“…A simple and ultrasensitive detection of human IgG based on signal amplification using a novel bio-barcode assay and DNA chip technology was developed. The…”
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Local gene delivery via endovascular stents coated with dodecylated chitosan-plasmid DNA nanoparticles by Zhu, Dunwan, Jin, Xu, Leng, Xigang, Wang, Hai, Bao, Junbo, Liu, Wenguang, Yao, Kangde, Song, Cunxian

“…Development of efficacious therapeutic strategies to prevent and inhibit the occurrences of restenosis after percutaneous transluminal coronary angioplasty is…”
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Evaluation of the coagulation properties of arginine-chitosan/DNA nanoparticles by Song, Liping, Zhu, Dunwan, Liu, Lanxia, Dong, Xia, Zhang, Hailing, Leng, Xigang

“…Arginine‐chitosan conjugate (Arg‐CS) was demonstrated to mediate significantly elevated expression of the transgenes in comparison to chitosan (CS). However,…”
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A biodegradable levonorgestrel-releasing implant made of PCL/F68 compound as tested in rats and dogs by Ma, Guilei, Song, Cunxian, Sun, Hongfan, Yang, Jing, Leng, Xigang

“…Our objective was to report preclinical studies on a biodegradable long-acting contraceptive implant. A poly (ε-caprolactone) (PCL)/pluronic F68 (F68) compound…”
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Evaluation of the impact of arginine-chitosan/DNA nanoparticles on human naive CD4+ T cells by Liu, Lanxia, Bai, Yuanyuan, Zhu, Dunwan, Song, Liping, Wang, Hai, Dong, Xia, Zhang, Hailing, Leng, Xigang

“…Previous studies showed that arginine‐conjugated chitosan (ACS)/DNA nanoparticles (ACGN) mediated significantly higher expression of the transgenes when…”
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Hydrophilic/lipophilic N-methylene phosphonic chitosan as a promising non-viral vector for gene delivery by Zhu, Dunwan, Yao, Kangde, Bo, Jingen, Zhang, Hailing, Liu, Lanxia, Dong, Xia, Song, Liping, Leng, Xigang

“…Cationic amphiphilic drugs have recently been shown to inhibit receptor recycling by disrupting the assembly–disassembly of clathrin at the plasma membrane and…”
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Immobilization of plasmid DNA on an anti-DNA antibody modified coronary stent for intravascular site-specific gene therapy by Jin, Xu, Mei, Lin, Song, Cunxian, Liu, Lanxia, Leng, Xigang, Sun, Hongfan, Kong, Deling, Levy, Robert J.

“…Background The aim of the present study was to investigate the incorporation of plasmid DNA (pDNA) onto a coronary stent by chemo‐immunoconjugation for…”
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An innovative MWCNTs/DOX/TC nanosystem for chemo-photothermal combination therapy of cancer by Dong, Xia, Sun, Zhiting, Wang, Xiaoxiao, Leng, Xigang

“…Chemotherapy and photothermal therapy can be efficiently integrated to achieve enhanced antitumor efficacy by using carbon nanotubes (CNTs) which are super in…”
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Targeted Codelivery of an Antigen and Dual Agonists by Hybrid Nanoparticles for Enhanced Cancer Immunotherapy by Zhang, Linhua, Wu, Shengjie, Qin, Yu, Fan, Fan, Zhang, Zhiming, Huang, Chenlu, Ji, Weihang, Lu, Lu, Wang, Chun, Sun, Hongfan, Leng, Xigang, Kong, Deling, Zhu, Dunwan

“…Among approaches of current cancer immunotherapy, a dendritic cell (DC)-targeted vaccine based on nanotechnology could be a promising way to efficiently induce…”
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ICG/l‑Arginine Encapsulated PLGA Nanoparticle-Thermosensitive Hydrogel Hybrid Delivery System for Cascade Cancer Photodynamic-NO Therapy with Promoted Collagen Depletion in Tumor Tissues by Sun, Zhiting, Wang, Xiaoxiao, Liu, Jing, Wang, Zhihong, Wang, Weiwei, Kong, Deling, Leng, Xigang

“…Photodynamic therapy (PDT) is promising for clinical cancer therapy; however, the efficacy was limited as an individual treatment regimen. Here, an approach…”
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