Search Results - "Lener, Marc S"

In pursuit of neuroimaging biomarkers to guide treatment selection in major depressive disorder: a review of the literature by Lener, Marc S., Iosifescu, Dan V.

“…Over the last few decades, neuroimaging techniques have advanced the identification of structural, functional, and neurochemical brain abnormalities that are…”
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Ketamine and Beyond: Investigations into the Potential of Glutamatergic Agents to Treat Depression by Lener, Marc S., Kadriu, Bashkim, Zarate, Carlos A.

“…Clinical and preclinical studies suggest that dysfunction of the glutamatergic system is implicated in mood disorders such as major depressive disorder and…”
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Glutamate and Gamma-Aminobutyric Acid Systems in the Pathophysiology of Major Depression and Antidepressant Response to Ketamine by Lener, Marc S, Niciu, Mark J, Ballard, Elizabeth D, Park, Minkyung, Park, Lawrence T, Nugent, Allison C, Zarate, Carlos A

“…Abstract In patients with major depressive disorder or bipolar disorder, abnormalities in excitatory and/or inhibitory neurotransmission and neuronal…”
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Parsing the heterogeneity of depression: An exploratory factor analysis across commonly used depression rating scales by Ballard, Elizabeth D., Yarrington, Julia S., Farmer, Cristan A., Lener, Marc S., Kadriu, Bashkim, Lally, Níall, Williams, Deonte, Machado-Vieira, Rodrigo, Niciu, Mark J., Park, Lawrence, Zarate, Carlos A.

“…Due to the heterogeneity of depressive symptoms—which can include depressed mood, anhedonia, negative cognitive biases, and altered activity levels—researchers…”
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Cortical abnormalities and association with symptom dimensions across the depressive spectrum by Lener, Marc S, Kundu, Prantik, Wong, Edmund, Dewilde, Kaitlin E, Tang, Cheuk Y, Balchandani, Priti, Murrough, James W

“…Abstract Background Few studies have investigated the relationship between structural brain abnormalities and dimensions of depressive symptomatology. Methods…”
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Neurophysiological Changes Associated with Antidepressant Response to Ketamine Not Observed in a Negative Trial of Scopolamine in Major Depressive Disorder by Park, Lawrence, Furey, Maura, Nugent, Allison C, Farmer, Cristan, Ellis, Jessica, Szczepanik, Joanna, Lener, Marc S, Zarate, Jr, Carlos A

“…This randomized, placebo-controlled, crossover trial examined the antidepressant efficacy of the muscarinic antagonist scopolamine in major depressive disorder…”
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A Double-Blind, Placebo-Controlled, Pilot Study of Riluzole Monotherapy for Acute Bipolar Depression by Park, Lawrence T, Lener, Marc S, Hopkins, Matthew, Iadorola, Nicolas, Machado-Vieira, Rodrigo, Ballard, Elizabeth, Nugent, Allison, Zarate, Jr, Carlos A

“…Glutamatergic system abnormalities are implicated in the pathophysiology and treatment of both major depressive disorder and bipolar depression (BDep)…”
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White matter abnormalities in schizophrenia and schizotypal personality disorder by Lener, Marc S, Wong, Edmund, Tang, Cheuk Y, Byne, William, Goldstein, Kim E, Blair, Nicholas J, Haznedar, M Mehmet, New, Antonia S, Chemerinski, Eran, Chu, King-Wai, Rimsky, Liza S, Siever, Larry J, Koenigsberg, Harold W, Hazlett, Erin A

“…Prior diffusion tensor imaging (DTI) studies examining schizotypal personality disorder (SPD) and schizophrenia, separately have shown that compared with…”
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Clinical Trial of the Potassium Channel Activator Diazoxide for Major Depressive Disorder Halted Due to Intolerability by Kadriu, Bashkim, Yuan, Shiwen, Farmer, Cristan, Nugent, Allison C, Lener, Marc S, Niciu, Mark J, Park, Minkyung, Yazdian, Aaron, Ballard, Elizabeth D, Henn, Fritz A, Henter, Ioline D, Park, Lawrence T, Zarate, Jr, Carlos A

“…Some glutamatergic modulators have demonstrated rapid and relatively sustained antidepressant properties in patients with major depressive disorder. Because…”
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Handedness, heritability, neurocognition and brain asymmetry in schizophrenia by Deep-Soboslay, Amy, Hyde, Thomas M., Callicott, Joseph P., Lener, Marc S., Verchinski, Beth A., Apud, José A., Weinberger, Daniel R., Elvevåg, Brita

“…Higher rates of non-right-handedness (i.e. left- and mixed-handedness) have been reported in schizophrenia and have been a centrepiece for theories of…”
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Acute ketamine administration corrects abnormal inflammatory bone markers in major depressive disorder by Kadriu, B, Gold, P W, Luckenbaugh, D A, Lener, M S, Ballard, E D, Niciu, M J, Henter, I D, Park, L T, De Sousa, R T, Yuan, P, Machado-Vieira, R, Zarate, C A

“…Patients with major depressive disorder (MDD) have clinically relevant, significant decreases in bone mineral density (BMD). We sought to determine if…”
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Glutamate and GABA Systems in the Pathophysiology of Major Depression and Antidepressant Response to Ketamine by Lener, Marc S., Niciu, Mark J., Ballard, Elizabeth D., Park, Minkyung, Park, Lawrence T., Nugent, Allison, Zarate, Carlos A.

“…In patients with major depressive disorder (MDD) or bipolar disorder (BD), abnormalities in excitatory and/or inhibitory neurotransmission and neuronal…”
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