Search Results - "Lenart, Jakub"
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Beyond Self-Resistance: ABCF ATPase LmrC Is a Signal-Transducing Component of an Antibiotic-Driven Signaling Cascade Accelerating the Onset of Lincomycin Biosynthesis
Published in mBio (26-10-2021)“…In natural environments, antibiotics are important means of interspecies competition. At subinhibitory concentrations, they act as cues or signals inducing…”
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Detailed mutational analysis of Vga(A) interdomain linker: implication for antibiotic resistance specificity and mechanism
Published in Antimicrobial agents and chemotherapy (01-02-2015)“…Detailed mutational analysis examines the roles of individual residues of the Vga(A) linker in determining the antibiotic resistance phenotype. It defines a…”
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Ribosome-Mediated Attenuation of vga (A) Expression Is Shaped by the Antibiotic Resistance Specificity of Vga(A) Protein Variants
Published in Antimicrobial agents and chemotherapy (20-10-2020)“…Vga(A) protein variants confer different levels of resistance to lincosamides, streptogramin A, and pleuromutilins (LS P) by displacing antibiotics from the…”
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ClpP-independent function of ClpX interferes with telithromycin resistance conferred by Msr(A) in Staphylococcus aureus
Published in Antimicrobial agents and chemotherapy (01-06-2015)“…The ABCF family protein Msr(A) confers high resistance to macrolides but only low resistance to ketolides in staphylococci. Mutations in conserved functional…”
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Nencki Genomics Database--Ensembl funcgen enhanced with intersections, user data and genome-wide TFBS motifs
Published in Database : the journal of biological databases and curation (2013)“…We present the Nencki Genomics Database, which extends the functionality of Ensembl Regulatory Build (funcgen) for the three species: human, mouse and rat. The…”
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