Search Results - "Lenarsky, Carl"
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Translocation (4;19)(q35;q13.1)–Associated Primitive round Cell Sarcoma: Report of a Case and Review of the Literature
Published in Pediatric and developmental pathology (01-05-2008)“…We report the 4th case of a primitive round cell sarcoma with the translocation (4;19)(q35;q13.1) as the primary cytogenetic abnormality. This undifferentiated…”
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Three-year Follow up of GMCSF/bi-shRNA(furin) DNA-transfected Autologous Tumor Immunotherapy (Vigil) in Metastatic Advanced Ewing's Sarcoma
Published in Molecular therapy (01-08-2016)“…Ewing's sarcoma is a devastating rare pediatric cancer of the bone. Intense chemotherapy temporarily controls disease in most patients at presentation but has…”
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Pilot Trial of FANG Immunotherapy in Ewing's Sarcoma
Published in Molecular therapy (01-06-2015)“…We report on 12 consecutive patients with advanced/metastatic Ewing's sarcoma who were treated as a separate cohort of a phase 1 trial of FANG autologous…”
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Three-year Follow up of GMCSF/bi-shRNA super(furin) DNA-transfected Autologous Tumor Immunotherapy (Vigil) in Metastatic Advanced Ewing's Sarcoma
Published in Molecular therapy (01-08-2016)“…Ewing's sarcoma is a devastating rare pediatric cancer of the bone. Intense chemotherapy temporarily controls disease in most patients at presentation but has…”
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Three-year Follow up of GMCSF/bi-shRNAfurin DNA-transfected Autologous Tumor Immunotherapy (Vigil) in Metastatic Advanced Ewing's Sarcoma
Published in Molecular therapy (01-08-2016)“…Ewing's sarcoma is a devastating rare pediatric cancer of the bone. Intense chemotherapy temporarily controls disease in most patients at presentation but has…”
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Pilot Trial of FANG Immunotherapy in Ewing's Sarcoma super(MT)Open
Published in Molecular therapy (01-06-2015)“…We report on 12 consecutive patients with advanced/metastatic Ewing's sarcoma who were treated as a separate cohort of a phase 1 trial of FANG autologous…”
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Shedding of GD2 ganglioside by human neuroblastoma
Published in International journal of cancer (15-01-1987)“…Substantial concentrations of the cell-surface glycosphingolipid, the disialoganglioside GD2, are uniformly present in human neuroblastoma tumors. This…”
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Pilot trial of vigil immunotherapy in Ewing’s sarcoma
Published in Journal of clinical oncology (20-05-2015)“…Abstract only…”
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Hurler Syndrome: II. Outcome of HLA-Genotypically Identical Sibling and HLA-Haploidentical Related Donor Bone Marrow Transplantation in Fifty-Four Children
Published in Blood (01-04-1998)“…Untreated patients with Hurler syndrome (MPSIH) experience progressive neurologic deterioration and early death. Allogeneic bone marrow transplantation (BMT)…”
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Hurler Syndrome: II. Outcome of HLA-Genotypically Identical Sibling and HLA-Haploidentical Related Donor Bone Marrow Transplantation in Fifty-Four Children
Published in Blood (01-04-1998)“…Untreated patients with Hurler syndrome (MPSIH) experience progressive neurologic deterioration and early death. Allogeneic bone marrow transplantation (BMT)…”
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Engraftment of gene-modified umbilical cord blood cells in neonates with adenosine deaminase deficiency
Published in Nature medicine (01-10-1995)“…Haematopoietic stem cells in umbilical cord blood are an attractive target for gene therapy of inborn errors of metabolism. Three neonates with severe combined…”
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Outcome of Unrelated Donor Bone Marrow Transplantation in 40 Children With Hurler Syndrome
Published in Blood (01-06-1996)“…Long-term survival and improved neuropsychological function have occurred in selected children with Hurler syndrome (MPS I H) after successful engraftment with…”
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Pre- and post-natal treatment of hemophagocytic lymphohistiocytosis
Published in Pediatric Blood & Cancer (01-01-2009)“…Hemophagocytic lymphohistiocytosis (HLH) is a rare autosomal recessive disorder of infancy and childhood that is invariably fatal if not treated. We report on…”
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Neurologic Complications After Allogeneic Marrow Transplantation for Sickle Cell Anemia
Published in Blood (15-02-1995)“…Seven of 21 patients with sickle cell anemia developed neurologic complications 5 to 243 days (median, 33 days) after allogeneic marrow transplantation. Among…”
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Busulfan and cyclophosphamide as a conditioning regimen for pediatric acute lymphoblastic leukemia patients undergoing bone marrow transplantation
Published in Journal of pediatric hematology/oncology (01-02-2004)“…Bone marrow transplantation (BMT) has become the standard therapy for children with relapsed acute lymphoblastic leukemia. The authors report their experience…”
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Immune recovery after bone marrow transplantation
Published in Current opinion in hematology (1995)“…Bone marrow transplantation usually entails the ablation of the recipient's immune system. The recovery of immunity after marrow transplantation is a complex…”
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T lymphocyte ontogeny in adenosine deaminase-deficient severe combined immune deficiency after treatment with polyethylene glycol-modified adenosine deaminase
Published in The Journal of clinical investigation (01-08-1993)“…Adenosine deaminase (ADA) deficiency causes severe combined immune deficiency (SCID) by interfering with the metabolism of deoxyadenosine, which is toxic to T…”
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Feasibility study of IL-11 and granulocyte colony-stimulating factor after myelosuppressive chemotherapy to mobilize peripheral blood stem cells from heavily pretreated Patients
Published in Journal of pediatric hematology/oncology (01-06-2001)“…Pediatric patients with solid tumors treated with prolonged dose-intensive chemoradiotherapy are poor mobilizers of peripheral blood stem cells (PBSC). We have…”
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Retroviral mediated transfer of the cDNA for human glucocerebrosidase into hematopoietic stem cells of patients with Gaucher disease. A phase I study
Published in Human gene therapy (20-01-1996)“…Patients with Gaucher disease suffer from a lack of functional glucocerebrosidase enzyme (Gc). Disease symptoms are a result of macrophage engorgement…”
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