Search Results - "Lena, A.M"

MicroRNA-191 triggers keratinocytes senescence by SATB1 and CDK6 downregulation by Lena, A.M., Mancini, M., Rivetti di Val Cervo, P., Saintigny, G., Mahé, C., Melino, G., Candi, E.

“…► miR-191 expression is upregulated in senescencent human epidermal keratinocytes. ► miR-191 overexpression is sufficient per se to induce senescence in…”
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MicroRNAs, miR-154, miR-299-5p, miR-376a, miR-376c, miR-377, miR-381, miR-487b, miR-485-3p, miR-495 and miR-654-3p, mapped to the 14q32.31 locus, regulate proliferation, apoptosis, migration and invasion in metastatic prostate cancer cells by Formosa, A, Markert, E K, Lena, A M, Italiano, D, Finazzi-Agro', E, Levine, A J, Bernardini, S, Garabadgiu, A V, Melino, G, Candi, E

“…miRNAs act as oncogenes or tumor suppressors in a wide variety of human cancers, including prostate cancer (PCa). We found a severe and consistent…”
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DNA methylation silences miR-132 in prostate cancer by Formosa, A, Lena, A M, Markert, E K, Cortelli, S, Miano, R, Mauriello, A, Croce, N, Vandesompele, J, Mestdagh, P, Finazzi-Agrò, E, Levine, A J, Melino, G, Bernardini, S, Candi, E

“…Silencing of microRNAs (miRNAs) by promoter CpG island methylation may be an important mechanism in prostate carcinogenesis. To screen for epigenetically…”
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ΔNp63 targets cytoglobin to inhibit oxidative stress-induced apoptosis in keratinocytes and lung cancer by Latina, A, Viticchiè, G, Lena, A M, Piro, M C, Annicchiarico-Petruzzelli, M, Melino, G, Candi, E

“…During physiological aerobic metabolism, the epidermis undergoes significant oxidative stress as a result of the production of reactive oxygen species (ROS)…”
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bromodomain of Gcn5p interacts in vitro with specific residues in the N terminus of histone H4 by Ornaghi, P, Ballario, P, Lena, A.M, Gonzalez, A, Filetici, P

“…Whereas the histone acetyltransferase activity of yeast Gcn5p has been widely studied, its structural interactions with the histones and the role of the…”
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