Search Results - "Lemus, Nicolas"

Roles and dynamics of 3-methylcytidine in cellular RNAs by Bohnsack, Katherine E., Kleiber, Nicole, Lemus-Diaz, Nicolas, Bohnsack, Markus T.

“…Modified nucleotides within cellular RNAs significantly influence their biogenesis, stability, and function. As reviewed here, 3-methylcytidine (m3C) has…”
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Interictal epileptiform discharges in Alzheimer's disease: prevalence, relevance, and controversies by Lemus, Hernan Nicolas, Sarkis, Rani A

“…Alzheimer's disease (AD) is the most common type of dementia and remains an incurable, progressive disease with limited disease-modifying interventions…”
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The RNA methyltransferase METTL8 installs m3C32 in mitochondrial tRNAsThr/Ser(UCN) to optimise tRNA structure and mitochondrial translation by Kleiber, Nicole, Lemus-Diaz, Nicolas, Stiller, Carina, Heinrichs, Marleen, Mai, Mandy Mong-Quyen, Hackert, Philipp, Richter-Dennerlein, Ricarda, Höbartner, Claudia, Bohnsack, Katherine E., Bohnsack, Markus T.

“…Modified nucleotides in tRNAs are important determinants of folding, structure and function. Here we identify METTL8 as a mitochondrial matrix protein and…”
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Ictal head roll: a seizure semiology from the anterior prefrontal lobe by Tantillo, Gabriela, Lemus, Hernan Nicolas, Jetté, Nathalie, Ghatan, Saadi, Panov, Fedor, Bolden, Dina, Fields, Madeline C.

“…Longstanding epilepsy can lead to modulation of cortical networks over time and unexpected seizure onset zones. Frontal lobe seizures, in particular, can have…”
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Fructosuria and recurrent hypoglycemia in a patient with a novel c.1693T>A variant in the 3′ untranslated region of the aldolase B gene by Morales-Alvarez, Martha Catalina, Ricardo-Silgado, Maria Laura, Lemus, Hernan Nicolas, González-Devia, Deyanira, Mendivil, Carlos O

“…Hereditary fructose intolerance, caused by mutations in the ALDOB gene, is an unusual cause of hypoglycemia. ALDOB encodes the enzyme aldolase B, responsible…”
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In-hospital outcomes in patients with and without epilepsy diagnosed with COVID-19-A cohort study by Ufongene, Claire, Van Hyfte, Grace, Agarwal, Parul, Blank, Leah J, Goldstein, Jonathan, Mathew, Brian, Lin, Jung-Yi, Navis, Allison, McCarthy, Louise, Gururangan, Kapil, Peschansky, Veronica, Kwon, Churl-Su, Cohen, Ariella, Chan, Andy Ho Wing, Dhamoon, Mandip, Deng, Pojen, Gutzwiller, Eveline M, Hao, Qing, He, Celestine, Heredia Nunez, Wilson D, Klenofsky, Britany, Lemus, Hernan Nicolas, Marcuse, Lara, Roberts, Mallory, Schorr, Emily M, Singh, Anuradha, Tantillo, Gabriela, Young, James, Balchandani, Priti, Festa, Joanne, Naasan, Georges, Charney, Alexander, Nadkarni, Girish, Jetté, Nathalie

“…Coronavirus disease 2019 (COVID-19) is associated with mortality in persons with comorbidities. The aim of this study was to evaluate in-hospital outcomes in…”
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Gastric Antral Vascular Ectasia in Systemic Sclerosis: Current Concepts by Quintana López, Gerardo, Coral-Alvarado, Paola Ximena, Lemus, Hernan Nicolas, Parrado, Raphael Hernando

“…Introduction. Gastric antral vascular ectasia (GAVE) is a rare entity with unique endoscopic appearance described as “watermelon stomach.” It has been…”
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Refractory Seizures Secondary to Vitamin B6 Deficiency in Parkinson Disease: The Role of Carbidopa-Levodopa by Wise, Adina, Lemus, Hernan Nicolas, Fields, Madeline, Swan, Matthew, Bressman, Susan

“…Carbidopa-levodopa has been used for more than 50 years in the treatment of Parkinson disease (PD) and other movement disorders. Pyridoxal 5′-phosphate (PLP),…”
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Chile's report card on physical activity: contributing to a global initiative for more active children and adolescents by Aguilar-Farías, Nicolás, Cortínez, Andrea, Leppe-Zamora, Jaime, Balboa, Teresa, Cobos, Carolina, Lemus, Nicolás, Valladares, Macarena, Sadarangani, Kabir, Von Oetinger, Astrid, Walbaum, Magdalena, Cristi-Montero, Carlos

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Dual Fluorescence Reporter Based Analytical Flow Cytometry for miRNA Induced Regulation in Mammalian Cells by Lemus-Diaz, Nicolas, Tamon, Liezel, Gruber, Jens

“…MicroRNA-induced gene regulation is a growing field in basic and translational research. Examining this regulation directly in cells is necessary to validate…”
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Effects of RANKL Knockdown by Virus-like Particle-Mediated RNAi in a Rat Model of Osteoporosis by Hoffmann, Daniel B., Gruber, Jens, Böker, Kai O., Deppe, Delia, Sehmisch, Stephan, Schilling, Arndt F., Lemus-Diaz, Nicolas, Komrakova, Marina, Schneider, Stefan

“…Rebalancing of the RANKL/OPG system seems to be an effective treatment strategy in postmenopausal osteoporosis. Here, we evaluate the knockdown of RANKL by…”
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An Assay that Predicts In Vivo Efficacy for DNA Aptamers that Stimulate Remyelination in a Mouse Model of Multiple Sclerosis by Heider, Robin M, Smestad, John A, Lemus, Hernan Nicolas, Wilbanks, Brandon, Warrington, Arthur E, Peters, Justin P, Rodriguez, Moses, Maher, 3rd, L James

“…Multiple sclerosis (MS) is a debilitating disease for which regenerative therapies are sought. We have previously described human antibodies and DNA…”
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Integrated Analysis of Transcriptome and Secretome From Umbilical Cord Mesenchymal Stromal Cells Reveal New Mechanisms for the Modulation of Inflammation and Immune Activation by Cruz-Barrera, Mónica, Flórez-Zapata, Nathalia, Lemus-Diaz, Nicolás, Medina, Carlos, Galindo, Cristian-Camilo, González-Acero, Lorena-Xiomara, Correa, Luz, Camacho, Bernardo, Gruber, Jens, Salguero, Gustavo

“…Mesenchymal stromal cells (MSC) have been used in over 800 clinical trials with encouraging results in the field of transplant medicine and chronic…”
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Enhanced Production of Exosome-Associated AAV by Overexpression of the Tetraspanin CD9 by Schiller, Lara Timantra, Lemus-Diaz, Nicolás, Rinaldi Ferreira, Rafael, Böker, Kai Oliver, Gruber, Jens

“…Research on cell-free vesicles revealed a multitude of characteristics, in particular of microvesicles and exosomes, that range from their potential as…”
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Pregnancy Seizure Outcomes for Epilepsy Patients with Catamenial Seizure Exacerbation (P8-1.011) by Voinescu, Paula, Esquivel, Hernan Nicolas Lemus, Liu, Lena, Allien, Stephanie, Pennell, Page

“…Abstract only…”
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Readmissions for Cardiac and Non-cardiac Causes Among those with Epilepsy or Multiple Sclerosis (5029) by Esquivel, Hernan Nicolas Lemus, Agarwal, Parul, Kwon, Churl-Su, Yeshokumar, Anusha, Dhamoon, Mandip, Mazumdar, Madhu, Jette, Nathalie

“…Abstract only…”
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The Effects of Paternal Seizure Disorders and Antiseizure Medication Use on Offspring Neurodevelopmental Outcomes, Psychiatric Comorbidities, and Sexual Health. (4262) by Esquivel, Hernan Nicolas Lemus, Casale, Marc, Young, James, Marcuse, Lara, Yoo, Ji-Yeoun, Mueller, Bridget, Fields, Madeline

“…Abstract only…”
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Results From Chile's 2016 Report Card on Physical Activity for Children and Youth by Aguilar-Farias, Nicolas, Cortinez-O'Ryan, Andrea, Sadarangani, Kabir P, Von Oetinger, Astrid, Leppe, Jaime, Valladares, Macarena, Balboa-Castillo, Teresa, Cobos, Carolina, Lemus, Nicolas, Walbaum, Magdalena, Cristi-Montero, Carlos

“…The 2016 Chilean Report Card on Physical Activity for Children and Youth is a review of the evidence across indicators of behaviors, settings, and sources of…”
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Multiple Sclerosis: Mechanisms of Disease and Strategies for Myelin and Axonal Repair by Lemus, Hernan Nicolas, Warrington, Arthur E, Rodriguez, Moses

“…Multiple sclerosis is an inflammatory demyelinating disease of the central nervous system with a variety of presentations and unclear pathogenesis. Multiple…”
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Epilepsy care in nursing facilities: Knowledge gaps and opportunities by Lemus, Hernan Nicolas, Sarkis, Rani A.

“…•Epilepsy in the elderly is complex, often underdiagnosed, and inadequately treated.•Seizures in the elderly may be atypical and challenging to…”
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