Search Results - "Lemos, Janaina Alcântara"
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Carboxylated versus bisphosphonate SWCNT: Functionalization effects on the biocompatibility and in vivo behaviors in tumor-bearing mice
Published in Journal of drug delivery science and technology (01-04-2019)“…Single-walled carbon nanotubes (SWCNT) are raising interest in biomedical field, as a drug delivery system, due to their large payload capacity and rich…”
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Irinotecan-Loaded Polymeric Micelles as a Promising Alternative to Enhance Antitumor Efficacy in Colorectal Cancer Therapy
Published in Polymers (14-11-2022)“…Colorectal cancer has been considered a worldwide public health problem since current treatments are often ineffective. Irinotecan is a frontline…”
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Enhanced antitumor efficacy of lapachol-loaded nanoemulsion in breast cancer tumor model
Published in Biomedicine & pharmacotherapy (01-01-2021)“…[Display omitted] •The encapsulation of lapachol increased the blood circulation and tumor uptake.•Lapachol-loaded nanoemulsion therapy reduced the tumor…”
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pH-responsive and folate-coated liposomes encapsulating irinotecan as an alternative to improve efficacy of colorectal cancer treatment
Published in Biomedicine & pharmacotherapy (01-12-2021)“…Irinotecan (IRN) is a semisynthetic derivative of camptothecin that acts as a topoisomerase I inhibitor. IRN is used worldwide for the treatment of several…”
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Evaluation of acute toxicity and in vitro antitumor activity of a novel doxorubicin-loaded folate-coated pH-sensitive liposome
Published in Biomedicine & pharmacotherapy (01-09-2023)“…Doxorubicin (DOX) loaded liposomes have been used and studied in the last decades due to the significant decrease in DOX induced cardiac and systemic toxicity…”
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Recent progress in micro and nano-encapsulation of bioactive derivatives of the Brazilian genus Pterodon
Published in Biomedicine & pharmacotherapy (01-11-2021)“…In the last few decades, utilization of medicinal plants by the pharmaceutical industry has led to the identification of many new bioactive compounds. The…”
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Preclinical evaluation of L-fucoside from lapachol-loaded nanoemulsion as a strategy to breast cancer treatment
Published in Biomedicine & pharmacotherapy (01-01-2024)“…Breast cancer prevails as the most common cancer in women, underscoring an urgent need for more effective therapies. This study explores the potential of our…”
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Sucupira oleoresin-based doxorubicin pH-sensitive nanoemulsions: A potential nanomedicine approach to enhance the safety profile and anticancer activity
Published in Journal of drug delivery science and technology (01-11-2024)“…Plant derivatives-based nanocarriers as a matrix for delivery of chemotherapeutic drugs are capable of enhancing conventional antitumor drugs' cytotoxicity…”
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Optimization and in vitro/in vivo performance of paclitaxel-loaded nanostructured lipid carriers for breast cancer treatment
Published in Journal of drug delivery science and technology (01-12-2019)“…Despite the wide use of paclitaxel (PTX) as antitumor drug, its intravenous administration is still limited by the low aqueous solubility (<1.0 μg/mL; log…”
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Preclinical evaluation of PEG-Multiwalled carbon nanotubes: Radiolabeling, biodistribution and toxicity in mice
Published in Journal of drug delivery science and technology (01-09-2023)“…Multiwalled carbon nanotubes (MWCNTs) have been integrated into many recent biomedical studies since their cylindrical architecture, high aspect ratio, and…”
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