Phytochemical study of Harrisia adscendens

[Display omitted] Harrisia adscendens (Gürke) Britton & Rose is a species of the family Cactaceae found in the northeastern semi-arid and popularly known as foxtail. In folk medicine, the roots of this species are used for the treatment of toothache and heartburn. The objective of this study was...

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Published in:	Revista brasileira de farmacognosia Vol. 28; no. 3; pp. 298 - 302
Main Authors:	Santos, George Luís Dias dos, Lemos, Emerson Leite, Fernandes, Anna Flávia Costa, Rocha, Wilma Raianny Vieira da, Catão, Raïssa Mayer Ramalho, Filho, Raimundo Braz, Tavares, Josean Fechine, Fechine, Ivana Maria, Alves, Harley da Silva
Format:	Journal Article
Language:	English
Published:	Cham Elsevier Editora Ltda 01-05-2018 Springer International Publishing Sociedade Brasileira de Farmacognosia
Subjects:	Acetophenone Caatinga Cactus Original Article PHARMACOLOGY & PHARMACY Pharmacy β-Carboline alkaloid Acetophenone β-Carboline alkaloid Caatinga Cactus
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Summary:	[Display omitted] Harrisia adscendens (Gürke) Britton & Rose is a species of the family Cactaceae found in the northeastern semi-arid and popularly known as foxtail. In folk medicine, the roots of this species are used for the treatment of toothache and heartburn. The objective of this study was to perform the isolation and identification of the secondary metabolites obtained from the vegetal drug by chromatographic and spectroscopic techniques and to evaluate the antimicrobial activity of the extract. The qualitative phytochemical analysis of the extract showed suggestive results for the presence of alkaloids. Two compounds were isolated and identified: 2-methyl-9H-β-carboline-2-ion, a β-carboline alkaloid obtained for the first time as a natural product and 2′,6′-dihydroxy-4′-methoxyacetophenone-2′-O-β-glucoside. In the antimicrobial tests, it was possible to observe activity against Pseudomonas aeruginosa. The results obtained by spectroscopic techniques allowed to characterize the phytochemical properties of the vegetal drug and may be useful in future studies for production of herbal medicines.
ISSN:	0102-695X 1981-528X 1981-528X
DOI:	10.1016/j.bjp.2018.04.011