Search Results - "Lemons, Richard"
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IMPROVEMENT ROUTINES: RESEARCH BY AND FOR PRACTITIONERS
Published in Phi Delta Kappan (01-04-2021)“…The relationship between research and practice in K-12 is complicated and fraught. Research publications are unlikely to become more “user-friendly,” and…”
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Eltrombopag for children with chronic immune thrombocytopenia (PETIT2): a randomised, multicentre, placebo-controlled trial
Published in The Lancet (British edition) (24-10-2015)“…Summary Background The thrombopoietin receptor agonist eltrombopag has been shown to be safe, tolerable, and effective for adults with chronic immune…”
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3
Neonatal hemolytic jaundice: morphologic features of erythrocytes that will help you diagnose the underlying condition
Published in Neonatology (Basel, Switzerland) (01-01-2014)“…Many cases of severe neonatal hyperbilirubinemia never have the underlying cause of the jaundice clearly identified. Thus they are said to have 'idiopathic'…”
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Neonatal nonimmune hemolytic anemia
Published in Current opinion in pediatrics (01-02-2017)“…As in adults and older children, anemia in newborn infants can be the result of erythropoietic failure, hemorrhage, or hemolysis. When hemolysis is the prime…”
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Likelihood of Bone Recurrence in Prior Sites of Metastasis in Patients With High-Risk Neuroblastoma
Published in International journal of radiation oncology, biology, physics (15-07-2014)“…Purpose/Objectives Despite recent improvements in outcomes, 40% of children with high-risk neuroblastoma will experience relapse, facing a guarded prognosis…”
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Supportive care medications coinciding with chemotherapy among children with hematologic malignancy
Published in Leukemia & lymphoma (02-07-2020)“…Pharmacokinetic (PK) conflicts can arise between supportive care medications (SCM) and chemotherapy in children with hematologic malignancy (HM). In this…”
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Mapping the Evidence for Opioid-Mediated Changes in Malignancy and Chemotherapeutic Efficacy: Protocol for a Scoping Review
Published in JMIR research protocols (22-05-2023)“…Numerous reports contend opioids can augment or inhibit malignancy. At present, there is no consensus on the risk or benefit posed by opioids on malignancy or…”
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Safety and Efficacy of Recombinant Fusion Protein Linking Coagulation Factor IX with Albumin (rIX-FP) in Previously Untreated Patients with Hemophilia B
Published in TH open : companion journal to thrombosis and haemostasis (01-01-2024)“…Recombinant fusion protein linking coagulation factor IX (FIX) with albumin (rIX-FP) has been shown to be an effective, well-tolerated treatment for patients…”
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Dronabinol Prescribing and Exposure Among Children and Young Adults Diagnosed with Cancer
Published in Journal of adolescent and young adult oncology (01-04-2021)“…The therapeutic utility of in cancer is a topic of intense interest. Dronabinol is synthetic Δ -tetrahydrocannabinol (THC), the primary psychoactive component…”
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Oral Step-Down Therapy With Levofloxacin for Febrile Neutropenia in Children With Cancer
Published in Journal of the Pediatric Infectious Diseases Society (13-02-2021)“…Abstract Background Although febrile neutropenia (FN) is a frequent complication in children with cancer receiving chemotherapy, there remains significant…”
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Learning to Walk, Walking to Learn: Reconsidering the Walkthrough as an Improvement Strategy
Published in Phi Delta Kappan (01-03-2009)“…School leaders desperate for strategies that will improve student learning have often opted to embrace strategies that they have observed being used…”
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High-Throughput Detection of Glutathione S-Transferase Polymorphic Alleles in a Pediatric Cancer Population
Published in Cancer epidemiology, biomarkers & prevention (01-02-2004)“…Polymorphisms of glutathione S -transferase (GST) enzymes have been correlated with altered risk of several cancers, as well as altered response and toxicity…”
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Low-grade myofibrosarcoma of the head and neck: importance of surgical therapy
Published in Journal of pediatric hematology/oncology (01-02-2004)Get full text
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HIV Comorbid Infection and Liver-Directed AAV-Based Gene Therapy in Adults with Severe and Moderately Severe Hemophilia B: Efficacy and Safety Results from Phase 2b and the Pivotal Phase 3 HOPE-B Trials 3 Years after Administration of a Single Dose of Etranacogene Dezaparvovec
Published in Blood (02-11-2023)“…Introduction: People living with HIV represent an important subset within the hemophilia community. Concerns about increased hepatotoxicity of liver-directed…”
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Gene Therapy with Etranacogene Dezaparvovec for Hemophilia B
Published in The New England journal of medicine (23-02-2023)“…An AAV5 vector containing the factor IX Padua allele was administered to 54 men with hemophilia B. Factor IX expression increased to approximately 39% of…”
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Safety, dose, and timing of Reteplase in treating occluded central venous catheters in children with cancer
Published in Journal of pediatric hematology/oncology (01-11-2003)“…Recombinant tissue plasminogen activator, alteplase, began to be commonly used to restore the patency of occluded central venous catheters (CVCs) as urokinase…”
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Invasive procedures and surgery following etranacogene dezaparvovec gene therapy in people with hemophilia B
Published in Journal of thrombosis and haemostasis (26-09-2024)“…Little information regarding the management of invasive procedures in people with hemophilia B (HB) after undergoing gene therapy is available. Here, we report…”
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Long-Term Bleeding Protection, Sustained FIX Activity, Reduction of FIX Consumption and Safety of Hemophilia B Gene Therapy: Results from the HOPE-B Trial 3 Years after Administration of a Single Dose of Etranacogene Dezaparvovec in Adult Patients with Severe or Moderately Severe Hemophilia B
Published in Blood (02-11-2023)“…Introduction: Etranacogene dezaparvovec (formerly AMT-061) is the first approved gene therapy for hemophilia B in the US and Europe. It is an adeno-associated…”
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First Data from the Phase 3 HOPE-B Gene Therapy Trial: Efficacy and Safety of Etranacogene Dezaparvovec (AAV5-Padua hFIX variant; AMT-061) in Adults with Severe or Moderate-Severe Hemophilia B Treated Irrespective of Pre-Existing Anti-Capsid Neutralizing Antibodies
Published in Blood (19-11-2020)“…Background: Etranacogene dezaparvovec is an investigational gene therapy for hemophilia B (HB) comprising an adeno-associated virus serotype 5 (AAV5) vector…”
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Reduction in Inpatient Central Line Associated Blood Stream Infection Post Implementation of Bundled Care Measures in Patients with Benign and Malignant Hematological Conditions in a Single Pediatric Institution
Published in Blood (03-12-2015)“…Background: Central line associated blood stream infections (CLABSIs) are a significant source of morbidity, mortality and cost for pediatric…”
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