Search Results - "Lemoine, Mael"
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The advent of fear conditioning as an animal model of post-traumatic stress disorder: Learning from the past to shape the future of PTSD research
Published in Neuron (Cambridge, Mass.) (04-08-2021)“…Translational research on post-traumatic stress disorder (PTSD) has produced limited improvements in clinical practice. Fear conditioning (FC) is one of the…”
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The philosophy of science: a companion / edited by Anouk Barberousse, Denis Bonnay, and Mikael Cozic
Published 2018“…Philosophy of science studies the methods, theories and concepts used by scientists. This book addresses both general philosophy of science and specific…”
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The Evolution of the Hallmarks of Aging
Published in Frontiers in genetics (26-08-2021)“…The evolutionary theory of aging has set the foundations for a comprehensive understanding of aging. The biology of aging has listed and described the…”
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Defining aging
Published in Biology & philosophy (25-08-2020)“…Aging is an elusive property of life, and many important questions about aging depend on its definition. This article proposes to draw a definition from the…”
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A Baldwin interpretation of adult hippocampal neurogenesis: from functional relevance to physiopathology
Published in Molecular psychiatry (01-01-2022)“…Hippocampal adult neurogenesis has been associated to many cognitive, emotional, and behavioral functions and dysfunctions, and its status as a selected effect…”
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Criteria of validity for animal models of psychiatric disorders: focus on anxiety disorders and depression
Published in Biology of mood & anxiety disorders (07-11-2011)“…Animal models of psychiatric disorders are usually discussed with regard to three criteria first elaborated by Willner; face, predictive and construct…”
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Defining disease beyond conceptual analysis: an analysis of conceptual analysis in philosophy of medicine
Published in Theoretical medicine and bioethics (01-08-2013)“…Conceptual analysis of health and disease is portrayed as consisting in the confrontation of a set of criteria—a “definition”—with a set of cases, called…”
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Immunological exhaustion: How to make a disparate concept operational?
Published in PLoS pathogens (23-09-2021)“…In this essay, we show that 3 distinct approaches to immunological exhaustion coexist and that they only partially overlap, generating potential…”
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On the neurobiological redefinition of psychiatric symptoms: elimination, reduction, or what?
Published in Synthese (Dordrecht) (01-06-2019)“…Because biologization of psychiatric constructs does not involve derivation of laws, or reduce the number of entities involved, the traditional term of…”
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Anya Plutynski’s Explaining Cancer: Finding Order in Disorder
Published in Philosophy of medicine (17-05-2022)Get full text
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The prospects of precision psychiatry
Published in Theoretical medicine and bioethics (01-12-2021)“…Since the turn of the twenty-first century, biomedical psychiatry around the globe has embraced the so-called precision medicine paradigm, a model for medical…”
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Dissecting the Meanings of "Physiology" to Assess the Vitality of the Discipline
Published in Physiology (Bethesda, Md.) (01-07-2018)“…The vitality of physiology is currently under debate. Some say that physiology is a dying discipline in the era of molecular medicine and systems biology,…”
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The visibility of philosophy of science in the sciences, 1980–2018
Published in Synthese (Dordrecht) (01-12-2021)“…In this paper, we provide a macro level analysis of the visibility of philosophy of science in the sciences over the last four decades. Our quantitative…”
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Animal extrapolation in preclinical studies: An analysis of the tragic case of TGN1412
Published in Studies in history and philosophy of science. Part C, Studies in history and philosophy of biological and biomedical sciences (01-02-2017)“…According to the received view, the transportation view, animal extrapolation consists in inductive prediction of the outcome of a mechanism in a target, based…”
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Philosophy of medicine in 2021
Published in Theoretical medicine and bioethics (01-12-2021)Get full text
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Implications of COVID-19 for the management of patients with inflammatory rheumatic diseases
Published in Joint, bone, spine : revue du rhumatisme (01-05-2020)Get full text
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A dual decomposition strategy of both microbial and phenotypic components for a better understanding of causal claims
Published in Biology & philosophy (01-02-2020)“…In our commentary on Lynch et al.’s target paper (Biol Philos, 2019. https://doi.org/10.1007/s10539-019-9702-2 ), we focus on decomposition as a research…”
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How does a psychiatrist infer from an observed condition to a case of mental disorder?
Published in Journal of evaluation in clinical practice (01-10-2012)“…The main thesis of this paper is that mental health practitioners can legitimately infer that a patient's given condition is a case of mental disorder without…”
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Does Inflammation Contribute to Cancer Incidence and Mortality during Aging? A Conceptual Review
Published in Cancers (23-03-2022)“…Aging is associated with chronic low-grade inflammation, cancer incidence and mortality. As inflammation contributes to cancer initiation and progression, one…”
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L’anorexie mentale : une fatigue de ne pas être soi ?
Published in Annales médico psychologiques (01-12-2022)“…Le présent article comprend l’anorexie mentale comme une stratégie visant à se produire soi-même, en modelant le corps d’une manière déterminée, afin d’obtenir…”
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