Search Results - "Lemnge, M. M."

Estimating Medium- and Long-Term Trends in Malaria Transmission by Using Serological Markers of Malaria Exposure by Drakeley, C. J., Corran, P. H., Coleman, P. G., Tongren, J. E., McDonald, S. L. R., Carneiro, I., Malima, R., Lusingu, J., Manjurano, A., Nkya, W. M. M., Lemnge, M. M., Cox, J., Reyburn, H., Riley, E. M., Miller, Louis H.

“…The implementation and evaluation of malaria control programs would be greatly facilitated by new tools for the rapid assessment of malaria transmission…”
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Efficacy and safety of artemisinin-based combination therapy, and molecular markers for artemisinin and piperaquine resistance in Mainland Tanzania by Kakolwa, Mwaka A, Mahende, Muhidin K, Ishengoma, Deus S, Mandara, Celine I, Ngasala, Billy, Kamugisha, Erasmus, Kataraihya, Johannes B, Mandike, Renata, Mkude, Sigsbert, Chacky, Frank, Njau, Ritha, Premji, Zul, Lemnge, Martha M, Warsame, Marian, Menard, Didier, Kabanywanyi, Abdunoor M

“…Artemisinin-based combination therapy (ACT) is the first-line anti-malarial treatment of uncomplicated malaria in most malaria endemic countries, including…”
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High efficacy of artemether-lumefantrine and dihydroartemisinin-piperaquine for the treatment of uncomplicated falciparum malaria in Muheza and Kigoma Districts, Tanzania by Mandara, Celine I, Kavishe, Reginald A, Gesase, Samuel, Mghamba, Janneth, Ngadaya, Esther, Mmbuji, Peter, Mkude, Sigsbert, Mandike, Renata, Njau, Ritha, Mohamed, Ally, Lemnge, Martha M, Warsame, Marian, Ishengoma, Deus S

“…Artemether-lumefantrine (AL) is the recommended first-line artemisinin-based combination therapy (ACT) for the treatment of uncomplicated falciparum malaria in…”
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Population Pharmacokinetics of Intramuscular Artesunate in African Children With Severe Malaria: Implications for a Practical Dosing Regimen by Hendriksen, ICE, Mtove, G, Kent, A, Gesase, S, Reyburn, H, Lemnge, M M, Lindegardh, N, Day, N P J, von Seidlein, L, White, N J, Dondorp, A M, Tarning, J

“…Parenteral artesunate (ARS) is the drug of choice for the treatment of severe malaria. Pharmacokinetics data on intramuscular ARS are limited with respect to…”
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Efficacy of RTS,S/AS01E malaria vaccine and exploratory analysis on anti-circumsporozoite antibody titres and protection in children aged 5–17 months in Kenya and Tanzania: a randomised controlled trial by Olotu, Ally, Dr, Lusingu, John, PhD, Leach, Amanda, MRCPCH, Lievens, Marc, MSc, Vekemans, Johan, PhD, Msham, Salum, MD, Lang, Trudie, PhD, Gould, Jayne, PhD, Dubois, Marie-Claude, MSc, Jongert, Erik, PhD, Vansadia, Preeti, MHS, Carter, Terrell, MHS, Njuguna, Patricia, MMeD, Awuondo, Ken O, HND, Malabeja, Anangisye, MD, Abdul, Omar, MD, Gesase, Samwel, MD, Mturi, Neema, MRCPaed, Drakeley, Chris J, PhD, Savarese, Barbara, RN, Villafana, Tonya, PhD, Lapierre, Didier, PhD, Ballou, W Ripley, MD, Cohen, Joe, PhD, Lemnge, Martha M, PhD, Peshu, Norbert, MBChB, Marsh, Kevin, FRCP, Riley, Eleanor M, PhD, von Seidlein, Lorenz, PhD, Bejon, Philip, PhD

“…Summary Background RTS,S/AS01E is the lead candidate malaria vaccine. We recently showed efficacy against clinical falciparum malaria in 5–17 month old…”
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Deployment and use of mobile phone technology for real-time reporting of fever cases and malaria treatment failure in areas of declining malaria transmission in Muheza district north-eastern Tanzania by Francis, Filbert, Ishengoma, Deus S, Mmbando, Bruno P, Rutta, Acleus S M, Malecela, Mwelecele N, Mayala, Benjamin, Lemnge, Martha M, Michael, Edwin

“…Early detection of febrile illnesses at community level is essential for improved malaria case management and control. Currently, mobile phone-based technology…”
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Altitude-Dependent and -Independent Variations in Plasmodium falciparum Prevalence in Northeastern Tanzania by Drakeley, Chris J., Carneiro, Ilona, Reyburn, Hugh, Malima, Robert, Lusingu, John P. A., Cox, Jonathan, Theander, Thor G., Nkya, Watoky M. M. M., Lemnge, Martha M., Riley, Eleanor M.

“…Background. Effective malaria control requires information about intensity of transmission across large areas and populations. Estimates based on entomological…”
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Trends of Plasmodium falciparum prevalence in two communities of Muheza district North-eastern Tanzania: correlation between parasite prevalence, malaria interventions and rainfall in the context of re-emergence of malaria after two decades of progressively declining transmission by Ishengoma, Deus S, Mmbando, Bruno P, Mandara, Celine I, Chiduo, Mercy G, Francis, Filbert, Timiza, Wilbert, Msemo, Hellen, Kijazi, Agnes, Lemnge, Martha M, Malecela, Mwelecele N, Snow, Robert W, Alifrangis, Michael, Bygbjerg, Ib C

“…Although the recent decline of malaria burden in some African countries has been attributed to a scale-up of interventions, such as bed nets…”
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Pattern of all-causes and cause-specific mortality in an area with progressively declining malaria burden in Korogwe district, north-eastern Tanzania by Challe, Daniel P, Kamugisha, Mathias L, Mmbando, Bruno P, Francis, Filbert, Chiduo, Mercy G, Mandara, Celine I, Gesase, Samuel, Abdul, Omari, Lemnge, Martha M, Ishengoma, Deus S

“…Although death records are useful for planning and monitoring health interventions, such information is limited in most developing countries. Verbal autopsy…”
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A progressive declining in the burden of malaria in north-eastern Tanzania by Mmbando, Bruno P, Vestergaard, Lasse S, Kitua, Andrew Y, Lemnge, Martha M, Theander, Thor G, Lusingu, John P A

“…The planning and assessment of malaria interventions is complicated due to fluctuations in the burden of malaria over time. Recently, it has been reported that…”
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Independent origin of plasmodium falciparum antifolate super-resistance, Uganda, Tanzania, and Ethiopia by Alifrangis, Michael, Nag, Sidsel, Schousboe, Mette L, Ishengoma, Deus, Lusingu, John, Pota, Hirva, Kavishe, Reginald A, Pearce, Richard, Ord, Rosalynn, Lynch, Caroline, Dejene, Seyoum, Cox, Jonathan, Rwakimari, John, Minja, Daniel T R, Lemnge, Martha M, Roper, Cally

“…Super-resistant Plasmodium falciparum threatens the effectiveness of sulfadoxine-pyrimethamine in intermittent preventive treatment for malaria during…”
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Target Antigen, Age, and Duration of Antigen Exposure Independently Regulate Immunoglobulin G Subclass Switching in Malaria by Tongren, J. Eric, Drakeley, Christopher J, McDonald, Suzanna L. R, Reyburn, Hugh G, Manjurano, Alphaxard, Nkya, Watoky M. M, Lemnge, Martha M, Gowda, Channe D, Todd, Jim E, Corran, Patrick H, Riley, Eleanor M

“…The isotype/subclass of immunoglobulin determines antibody function, but rather little is known about factors that direct class switching in vivo. To evaluate…”
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Occurrence of the Southeast Asian/South American SVMNT Haplotype of the Chloroquine-Resistance Transporter Gene in Plasmodium falciparum in Tanzania by Alifrangis, Michael, Dalgaard, Michael B., Lusingu, John P., Vestergaard, Lasse S., Staalsoe, Trine, Jensen, Anja T. R., Enevold, Anders, Rønn, Anita M., Khalil, Insaf F., Warhurst, David C., Lemnge, Martha M., Theander, Thor G., Bygbjerg, Ib C.

“…Two main haplotypes, CVIET and SVMNT, of the Plasmodium falciparum chloroquine-resistance transporter gene (Pfcrt) are linked to 4-aminoquinoline resistance…”
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Plasma Cytokine Levels in Tanzanian HIV-1-Infected Adults and the Effect of Antiretroviral Treatment by Haissman, Judith M, Vestergaard, Lasse S, Sembuche, Samuel, Erikstrup, Christian, Mmbando, Bruno, Mtullu, Samuel, Lemnge, Martha M, Gerstoft, Jan, Ullum, Henrik

“…OBJECTIVE:To evaluate the role immune activation leading to the production and circulation of cytokines has in the pathogenesis of HIV infection in sub-Saharan…”
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Accuracy of malaria rapid diagnostic tests in community studies and their impact on treatment of malaria in an area with declining malaria burden in north-eastern Tanzania by Ishengoma, Deus S, Francis, Filbert, Mmbando, Bruno P, Lusingu, John P A, Magistrado, Pamela, Alifrangis, Michael, Theander, Thor G, Bygbjerg, Ib C, Lemnge, Martha M

“…Despite some problems related to accuracy and applicability of malaria rapid diagnostic tests (RDTs), they are currently the best option in areas with limited…”
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Population Pharmacokinetic and Pharmacodynamic Properties of Intramuscular Quinine in Tanzanian Children with Severe Falciparum Malaria by HENDRIKSEN, Ilse C. E, MAIGA, Deogratius, TARNING, Joel, WHITE, Nicholas J, LEMNGE, Martha M, MTOVE, George, GESASE, Samwel, REYBURN, Hugh, LINDEGARDH, Niklas, DAY, Nicholas P. J, VON SEIDLEIN, Lorenz, DONDORP, Arjen M

“…OA  Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Spatial variation and socio-economic determinants of Plasmodium falciparum infection in northeastern Tanzania by Mmbando, Bruno P, Kamugisha, Mathias L, Lusingu, John P, Francis, Filbert, Ishengoma, Deus S, Theander, Thor G, Lemnge, Martha M, Scheike, Thomas H

“…Malaria due to Plasmodium falciparum is the leading cause of morbidity and mortality in Tanzania. According to health statistics, malaria accounts for about…”
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Using rapid diagnostic tests as source of malaria parasite DNA for molecular analyses in the era of declining malaria prevalence by Ishengoma, Deus S, Lwitiho, Sudi, Madebe, Rashid A, Nyagonde, Nyagonde, Persson, Ola, Vestergaard, Lasse S, Bygbjerg, Ib C, Lemnge, Martha M, Alifrangis, Michael

“…Malaria prevalence has recently declined markedly in many parts of Tanzania and other sub-Saharan African countries due to scaling-up of control interventions…”
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Effect of intermittent treatment with amodiaquine on anaemia and malarial fevers in infants in Tanzania: a randomised placebo-controlled trial by Massaga, Julius J, Kitua, Andrew Y, Lemnge, Martha M, Akida, Jumaa A, Malle, Lincoln N, Rønn, Anita M, Theander, Thor G, Bygbjerg, IC

“…Malaria is a major cause of infant morbidity and mortality in sub-Saharan Africa, and is often complicated by severe anaemia. Resistance of Plasmodium…”
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Safety of the malaria vaccine candidate, RTS,S/AS01E in 5 to 17 month old Kenyan and Tanzanian Children by Lusingu, John, Olotu, Ally, Leach, Amanda, Lievens, Marc, Vekemans, Johan, Olivier, Aurélie, Benns, Sarah, Olomi, Raimos, Msham, Salum, Lang, Trudie, Gould, Jayne, Hallez, Karin, Guerra, Yolanda, Njuguna, Patricia, Awuondo, Ken O, Malabeja, Anangisye, Abdul, Omar, Gesase, Samwel, Dekker, Denise, Malle, Lincoln, Ismael, Sadiki, Mturi, Neema, Drakeley, Chris J, Savarese, Barbara, Villafana, Tonya, Ballou, W Ripley, Cohen, Joe, Riley, Eleanor M, Lemnge, Martha M, Marsh, Kevin, Bejon, Philip, von Seidlein, Lorenz

“…The malaria vaccine candidate, RTS,S/AS01(E), showed promising protective efficacy in a trial of Kenyan and Tanzanian children aged 5 to 17 months. Here we…”
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