Search Results - "Lemmer, Björn"

The Role of Circadian Rhythms in the Hypertension of Diabetes Mellitus and the Metabolic Syndrome by Lemmer, Björn, Oster, Henrik

“…Purpose of the Review Cellular circadian clocks regulate physiological functions during day and night. It has been convincingly demonstrated that hypertension…”
Get full text

Insufficient reply by Hermida et al. to the critical comments to the MAPEC and HYGIA studies by Lemmer, Björn, Middeke, Martin

“…The reply of Hermida et al. (2020) to our critical comments on the MAPEC and HYGIA Lemmer and Middeke (2020) studies in this Journal is insufficient and…”
Get more information

Effects of music composed by Mozart and Ligeti on blood pressure and heart rate circadian rhythms in normotensive and hypertensive rats by Lemmer, Björn

“…There is continuing discussion on the effect of music ("Mozart effect") on numerous functions in man and experimental animals. Radiotelemetry now allows one to…”
Get more information

Influence of acoustic stimulation on the circadian and ultradian rhythm of premature infants by Dorn, Franziska, Wirth, Lara, Gorbey, Stefan, Wege, Mirjam, Zemlin, Michael, Maier, Rolf F, Lemmer, Björn

“…The aim of the present study was to evaluate the development of the circadian rhythm of the salivary cortisol in premature infants and its correlation with the…”
Get more information

Circadian variations in exsorptive transport: in situ intestinal perfusion data and in vivo relevance by Okyar, Alper, Dressler, Cornelia, Hanafy, Abeer, Baktir, Gül, Lemmer, Björn, Spahn-Langguth, Hilde

“…The circadian timing system (CTS) governs the 24-h rhythm of the organism and, hence, also main pathways responsible for drug pharmacokinetics. P-glycoprotein…”
Get more information

Chronopharmacokinetics: Implications for Drug Treatment by Lemmer, Björn

“…Nearly all functions of the human body are organized across the 24 hours of the day. This is also true for functions involved in the regulation of…”
Get full text

Pineal volume and circadian melatonin profile in healthy volunteers: An interdisciplinary approach by Nölte, Ingo, Lütkhoff, Ann-Theres, Stuck, Boris A., Lemmer, Björn, Schredl, Michael, Findeisen, Peter, Groden, Christoph

“…Purpose To correlate pineal parenchyma volume (PP) to circadian melatonin profiles and to determine the 24‐hour melatonin per volume of pineal tissue (MLPV)…”
Get full text

Chronobiological data: advantages of telemetric monitoring and prospects of mathematical modeling by Blagonravov, Mikhail L., Lemmer, Björn, Bryk, Anna A., Goryachev, Vyacheslav A., Karimov, Abdukayum A., Chibisov, Sergey M.

“…Chronobiology and chronomedicine is a special part of biomedical sciences studying rhythmical patterns in physiological and pathological processes. In order to…”
Get full text

Down-Regulation of the Expression of Endothelial NO Synthase Is Likely to Contribute to Glucocorticoid-Mediated Hypertension by Wallerath, Thomas, Witte, Klaus, Schäfer, Stephan C., Schwarz, Petra M., Prellwitz, Winfried, Wohlfart, Paulus, Kleinert, Hartmut, Lehr, Hans-Anton, Lemmer, Björn, Förstermann, Ulrich

“…Hypertension is a side effect of systemically administered glucocorticoids, but the underlying molecular mechanism remains poorly understood. Ingestion of…”
Get full text

Circannual Rhythms and Interactions of Vitamin D Metabolites, Parathyroid Hormone, and Biochemical Markers of Skeletal Homeostasis: A Prospective Study by Woitge, Henning W., Knothe, Antje, Witte, Klaus, Schmidt‐Gayk, Heinrich, Ziegler, Reinhard, Lemmer, Björn, Seibel, Markus J.

“…Recent studies suggest a circannual pattern of bone turnover. To further investigate the underlying mechanisms, 41 healthy subjects (25‐80 years old) living in…”
Get full text

The importance of circadian rhythms on drug response in hypertension and coronary heart disease--from mice and man by Lemmer, Björn

“…The cardiovascular system is highly organised in time; blood pressure (BP), heart rate (HR), peripheral resistance, pressure and the release/activity of…”
Get full text

Discoveries of rhythms in human biological functions: a historical review by Lemmer, Björn

“…Though there are very early and ancient observations on the daily variation in physiological and pathophysiological functions (e.g., bronchial asthma), more…”
Get more information

G12-G13–LARG–mediated signaling in vascular smooth muscle is required for salt-induced hypertension by Wirth, Angela, Benyó, Zoltán, Lukasova, Martina, Leutgeb, Barbara, Wettschureck, Nina, Gorbey, Stefan, Örsy, Petra, Horváth, Béla, Maser-Gluth, Christiane, Greiner, Erich, Lemmer, Björn, Schütz, Günther, Gutkind, J. Silvio, Offermanns, Stefan

“…The tone of vascular smooth muscle cells is a primary determinant of the total peripheral vascular resistance and hence the arterial blood pressure. Most forms…”
Get full text

The sleep–wake cycle and sleeping pills by Lemmer, Björn

“…Abstract Sleeping pills are drugs which are used world-wide to combat sleep disturbances, and to prevent symptoms due to maladjustment to shiftwork or jet-lag…”
Get full text

Disturbance of circadian rhythms in analgosedated intensive care unit patients with and without craniocerebral injury by Paul, Torsten, Lemmer, Björn

“…Melatonin, cortisol, heart rate, blood pressure, spontaneous motor activity, and body temperature follow stable circadian rhythms in healthy individuals. These…”
Get more information

Dysfunction of Soluble Guanylyl Cyclase in Aorta and Kidney of Goto–Kakizaki Rats: Influence of Age and Diabetic State by Witte, Klaus, Jacke, Kerstin, Stahrenberg, Raoul, Arlt, Gerrit, Reitenbach, Ina, Schilling, Lothar, Lemmer, Björn

“…Type 2 diabetes mellitus is frequently associated with arterial hypertension. The mechanisms involved in this association are not known in detail, but…”
Get full text

Chronobiology and chronotherapy of ischemic heart disease by Portaluppi, Francesco, Lemmer, Björn

“…The occurrence of the clinical manifestations of ischemic heart disease (IHD) – myocardial ischemia and angina pectoris, acute myocardial infarction, and…”
Get full text

Superiority of radiotelemetry over the tail-cuff method in evaluating control and drug-induced data in cardiovascular functions by Lemmer, Björn

“…The aim of the study was to compare an often-used method to measure blood pressure (BP) using a tail-cuff (TC) device, with radiotelemetry (RT) which allows to…”
Get full text

Signal Transduction and Chronopharmacology of Regulation of Circadian Cardiovascular Rhythms in Animal Models of Human Hypertension by Lemmer, Björn

“…Inbred strains of rats can be used as models of human hypertension to evaluate mechanisms of regulation of the circadian rhythms underlying hypertension. Blood…”
Get full text

Chronopharmacology and controlled drug release by Lemmer, Björn

“…Circadian rhythms in the body are well established and are an important factor to consider when administering drugs. Many diseases display symptoms and onset…”
Get more information